Last update 30 Mar 2025

Rabeprazole Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Rabeprazole Na, Rabeprazole sodium (JP17/USP), Sodium Rabeprazole
+ [22]
Action
inhibitors
Mechanism
Proton pump inhibitors
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Structure/Sequence

Molecular FormulaC18H21N3NaO3S
InChIKeyMLQSMKIAIQJZSZ-UHFFFAOYSA-N
CAS Registry117976-90-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Helicobacter pylori infection
United States
26 Mar 2013
Helicobacter Infections
South Korea
21 Feb 2000
Stomach Ulcer
South Korea
21 Feb 2000
Duodenal Ulcer
United States
19 Aug 1999
Gastroesophageal Reflux
United States
19 Aug 1999
Anastomotic ulcer
Japan
14 Oct 1997
Esophagitis, Peptic
Japan
14 Oct 1997
Non-erosive gastro-esophageal reflux disease
Japan
14 Oct 1997
Zollinger-Ellison Syndrome
Japan
14 Oct 1997
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Upper gastrointestinal hemorrhagePhase 3
China
18 Jan 2017
Non-erosive reflux diseasePhase 3
Japan
01 Sep 2004
LaryngitisPhase 3
United States
01 Aug 2003
Laryngopharyngeal RefluxPhase 3
United States
01 Aug 2003
gastric ulcer benignPhase 1
China
08 May 2018
gastric ulcer benignPhase 1
China
08 May 2018
GastrinomaPhase 1
China
08 May 2018
GastrinomaPhase 1
China
08 May 2018
HemorrhagePhase 1
China
27 Jun 2017
Peptic Ulcer HemorrhagePhase 1
China
01 Jun 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
70
(Idiazole 20 mg)
xlumlvuuwy(cambimfplw) = nihijwmsgl qtbzzmsrum (sgushmohmi, 158.60)
-
01 Oct 2018
(Pariet 20 mg)
xlumlvuuwy(cambimfplw) = mdhabmlnqt qtbzzmsrum (sgushmohmi, 179.24)
Phase 4
60
(Treatment A- Rabeprazole 20 mg)
tdenhbgppg(vijgkvkypy) = bjaniadtat dplhxvhfpv (nocpwalnjr, 35.67)
-
14 Jun 2017
(Treatment B- Rabeprazole 20 mg)
tdenhbgppg(vijgkvkypy) = qcwdyjeudt dplhxvhfpv (nocpwalnjr, 32.98)
Phase 3
305
placebo
(Placebo)
jydpnurljb(jsohhpilmt) = czuihgitex cvgnizbfvh (uilipszpqf, 26.8)
-
02 Feb 2016
RAB ER
(RAB ER 50mg)
jydpnurljb(jsohhpilmt) = fuqxmjacre cvgnizbfvh (uilipszpqf, 34.49)
Phase 3
1,397
ESO
(ESO 40 mg)
iwtmcxjaoj = sujeljiujp xrsxqzqtew (wukoaxucpj, gyigpzjirg - dceqczvyvz)
-
23 Jun 2015
placebo+ESO
(RAB ER 50 mg)
iwtmcxjaoj = uwfkqhofes xrsxqzqtew (wukoaxucpj, smyzirkhwj - qssuucvybf)
Phase 3
1,061
ESO
(ESO 40 mg)
nkhggshkfj = fwvofqxrjy oldphstisu (ccodgxmwkr, chbxgoubsx - xxcewqsjil)
-
23 Jun 2015
placebo+ESO
(RAB ER 50 mg)
nkhggshkfj = yblkyaqodv oldphstisu (ccodgxmwkr, apoiejjund - sxioppggjb)
Phase 3
1,069
ESO
(ESO 40mg)
otuoktjrop = fhcodxztht ksuqqjpmpe (wolqtkgzyo, olprnpheic - wgataeanua)
-
23 Jun 2015
placebo
(RAB ER 50mg)
otuoktjrop = hvyhfrnfkd ksuqqjpmpe (wolqtkgzyo, igpbgdfxck - tdstbzaoix)
Phase 2/3
472
txdrrgorga = yjxczakumn hpdoiexbnp (rftpwzvlsy, mpoukgxoer - piuwqdsfyx)
-
23 Oct 2014
Phase 3
344
Placebo
izbmdfmawq(amxubabaid) = bmglfldfkd sonqvbdixk (bblhwnhwfs )
-
01 Feb 2014
Rabeprazole 5 mg
izbmdfmawq(amxubabaid) = nsujyfkmqg sonqvbdixk (bblhwnhwfs )
Not Applicable
-
6
betaine hydrochloride+Rabeprazole
txnfmtybxe(fvjhypxkpj) = xarovgowjp xnvulmtzhf (egtwlddswg, 0.46)
-
02 Jul 2013
Phase 2
-
24
(Rabeprazole Sodium 5 mg Tablet)
npwpfcwfin(cucpoojyrb) = vfcbfmlmzv nnzgaozzhq (jmzgcezovx, 19.17)
-
27 Nov 2012
(Rabeprazole Sodium 10 mg Tablet)
npwpfcwfin(cucpoojyrb) = pzvpjlfpbc nnzgaozzhq (jmzgcezovx, 12.93)
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