Teva Reports Fourth Quarter and Full Year 2022 Financial Results

08 Feb 2023

·www.tevapharm.com

Financial StatementExecutive ChangeBiosimilar

TEL AVIV, Israel--(BUSINESS WIRE)-- Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA) today reported results for the year and the quarter ended December 31, 2022.

View the Highlights: Q4 and Full Year 2022 Business Results Infographic

Q4 and FY 2022 highlights:

Q4 2022

FY 2022

Revenues

$3.9 billion

$14.9 billion

GAAP diluted loss per share

$(1.10)

$(2.12)

Non-GAAP diluted EPS

$0.71

$2.52

Cash flow generated from operating activities

$973 million

$1,590 million

Free cash flow

$1,140 million

$2,243 million

2023 business outlook:

Revenues are expected to be $14.8 - $15.4 billion

Adjusted EBITDA of $4.5 - $4.9 billion

Non-GAAP diluted EPS is expected to be $2.25 - $2.55

Free cash flow is expected to be $1.7 - $2.1 billion

"It is a huge pleasure to be leading the Company through my first reporting period as CEO of Teva. The tremendous work that has been done to get the business back to a solid foundation serves as excellent grounds to transition into a new path for growth.

In 2022, Teva Teva delivered solid results. Our key innovative brands, AUSTEDO® and AJOVY®, continued to drive growth, with AUSTEDO increasing 20% in the U.S. We expect continued expansion as this medicine addresses a still large unmet need for tardive dyskinesia patients.

Our generics business performed strongly in Europe and International Markets, growing 9% and 5% respectively, in local currency terms. We also continued to optimize our supply chain and manufacturing capabilities and reduced our net debt.

Looking ahead to 2023, I am especially enthusiastic about the progress of our innovative, biosimilars and generic pipelines, which include interesting and differentiated assets. As we work on an updated strategy, we are looking for opportunities to best position Teva for long-term growth and generate value to all stakeholders."

2022 Annual Consolidated Results

Revenues in 2022 were $14,925 million, a decrease of 6%, in U.S. dollars or 1% in local currency terms, compared to 2021, mainly due to lower revenues from COPAXONE® and certain respiratory products in our North America and Europe segments, generic products as well as BENDEKA® and TREANDA® in our North America segment, partially offset by higher revenues from generic products in our Europe and International Markets segments, and from our innovative products – AUSTEDO and AJOVY, and Anda.

Exchange rate movements during 2022, including hedging effects, negatively impacted revenues by $780 million, operating income by $247 million and non-GAAP operating income by $263 million, each as compared to 2021.

Gross profit was $6,973 million in 2022, a decrease of 8% compared to 2021. Gross profit margin was 46.7% in 2022, compared to 47.8% in 2021. Non-GAAPgross profit was $8,056 million in 2022, a decrease of 6% compared to 2021. Non-GAAPgross profit margin was 54.0% in 2022, compared to 54.2% in 2021. This decrease in both GAAP and non-GAAP gross profit margin was mainly due to lower revenues from COPAXONE and certain respiratory products in our North America and Europe segments, partially offset by higher revenues from AUSTEDO in North America and a favorable mix of generic products in our Europe segment.

Research and Development (R&D) expenses in 2022 were $838 million, a decrease of 13% compared to 2021. The decrease in R&D expenses in 2022 was mainly due to a decrease in several neuroscience projects (in the pain and migraine and headache therapeutic areas) and immunology (in the respiratory therapeutic area) as well as a decline in various generics projects, and an adjustment in payments pursuant to a contract with one of our R&D partners in 2022, partially offset by higher R&D expenses related to our biosimilar products pipeline.

Selling and Marketing (S&M) expenses in 2022 were $2,265 million, a decrease of 7% compared to 2021.

General and Administrative (G&A) expenses in 2022 were $1,180 million, an increase of 7% compared to 2021. This increase was related to proceeds received from Teva’s insurance carriers pursuant to a settlement reached on a derivative proceeding in the second quarter of 2021 related to the acquisition of Actavis Generics, as well as higher litigation fees in the second quarter of 2022.

Other income in 2022 was $107 million, compared to $98 million in 2021.

Operating loss was $2,099 million in 2022, compared to operating income of $1,716 million in 2021. Operating loss as a percentage of revenues was 14.1% in 2022, compared to operating income as a percentage of revenues of 10.8% in 2021. Operating loss in 2022 was mainly affected by goodwill impairment charges, and legal settlements and loss contingencies. Non-GAAPoperating income was $4,139 million in 2022, or 27.7% of revenues compared to $4,401 million, or 27.7% of revenues in 2021. Non-GAAP operating margin in 2022 was mainly affected by lower gross profit margin, as discussed above, offset by lower operating expenses as a percentage of revenues.

Adjusted EBITDA was $4,598 million in 2022, compared to $4,911 million in 2021.

In 2022, financial expenses, net were $966 million, compared to $1,058 million in 2021. Financial expenses in 2022 were mainly comprised of interest expenses and other bank charges of $930 million. Financial expenses in 2021 were mainly comprised of interest expenses and other bank charges of $891 million and loss on revaluations of marketable securities of $90 million.

In 2022, we recognized a tax benefit of $638 million, or 21%, on a pre-tax loss of $3,065 million. In 2021, we recognized a tax expense of $211 million, or 32%, on a pre-tax income of $658 million. Our tax rate for 2022 was lower than in 2021 mainly due to the realization of losses related to an investment in one of our U.S. subsidiaries, partially offset by a goodwill impairment charge that did not have a corresponding tax effect.

Non-GAAP tax rate for 2022 was 12%, compared to 16% in 2021. Our non-GAAP tax rate in 2022 was mainly affected by the realization of losses related to an investment in one of our U.S. subsidiaries, the mix of products we sold, interest expense disallowances and adjustments to valuation allowances on deferred tax assets.

Net loss attributable to Teva and diluted loss per share in 2022 were $2,353 million and $2.12, respectively, compared to net income attributable to Teva of $417 million and diluted income per share of $0.38 in 2021. Net loss in 2022 was mainly affected by goodwill impairment charges and legal settlements and loss contingencies, partially offset by a tax benefit. Non-GAAP net income attributable to Teva and non-GAAP diluted earnings per share in 2022 were $2,812 million and $2.52, respectively, compared to $2,855 million and $2.58 in 2021.

As of December 31, 2022 and 2021, the fully diluted sharecount for purposes of calculating our market capitalization was approximately 1,143 million and 1,128 million shares, respectively.

Non-GAAP information: net non-GAAP adjustments in 2022 were $5,166 million. Non-GAAP net income attributable to Teva and non-GAAP diluted EPS for the year were adjusted to exclude the following items:

Amortization of purchased intangible assets totaling $732 million, of which $649 million is included in cost of goods sold and the remaining $83 million in S&M expenses;

Legal settlements and loss contingencies of $2,082 million;

Goodwill impairment charges of $2,045 million;

Impairment of long-lived assets of $402 million;

Restructuring expenses of $146 million;

Costs related to regulatory actions taken in facilities of $7 million;

Equity compensation expenses of $124 million;

Contingent consideration expenses of $163 million;

Gain on sale of business of $47 million;

Accelerated depreciation of $117 million;

Financial expenses of $61 million;

Share in profits of associated companies, net of $22 million;

Items attributable to non-controlling interests of $96 million;

Other non-GAAP items of $465 million; and

Corresponding tax effects and unusual tax items amounted to income of $1,016 million.

We believe that excluding such items facilitates investors’ understanding of our business. Commencing the first quarter of 2022, we no longer exclude in-process research and development (“IPR&D”) acquired in development arrangements from our non-GAAP financial measures. In our comparable non-GAAP financial measures for 2021 we excluded $15 million IPR&D acquired in development arrangements. We are not recasting the non-GAAP presentation for 2021 since the adjustment is not significant. We made this change to our presentation of non-GAAP financial measures to improve comparability of our non-GAAP presentation to those of other companies in the pharmaceutical industry that made a similar change to their presentations beginning in the first quarter of 2022.

For a reconciliation of the U.S. GAAP results to the adjusted non-GAAP figures and for additional information, see the tables below and the information included under “Non-GAAP Financial Measures.” Investors should consider non-GAAP financial measures in addition to, and not as replacement for, or superior to, measures of financial performance prepared in accordance with GAAP.

Cash flow generated from operating activities in 2022 was $1,590 million, compared to $798 million in 2021. The increase in 2022 resulted mainly from the sale of accounts receivables under our U.S. securitization facility entered into in November 2022, and lower cash collections remitted to the owner of the receivables under our EU securitization program mainly due to exchange rate fluctuation, partially offset by an increase in inventory levels, as well as higher payments of legal settlements in connection with the opioids litigation.

Free cash flow (defined as cash flow generated from operating activities, cash used for capital investments, beneficial interest collected in exchange for securitized accounts receivables, proceeds from divestitures of businesses and other assets and cash used for acquisition of businesses, net of cash acquired) was $2,243 million in 2022, compared to $2,196 million in 2021. The increase in 2022 resulted mainly from an increase in cash flow generated from operating activities, partially offset by lower beneficial interest collected in exchange for securitized accounts receivables under our EU securitization program mainly due to exchange rate fluctuations, as well as lower proceeds from divestitures of businesses and other assets.

On November 7, 2022, Teva and a bankruptcy-remote special purpose vehicle (“SPV”) entered into an accounts receivable securitization facility (“AR Facility”) with PNC Bank, National Association (“PNC”) with a three-year term. The AR Facility provides for purchases of accounts receivable by PNC in an amount of up to $1 billion through November 2023, and up to $500 million from November 2023 through November 2025, provided that the SPV may increase the commitment amount up to $1 billion if additional credit providers participate in the AR facility. The total balance of accounts receivables sold to PNC as of December 31, 2022 was $820 million which were derecognized by the SPV. In addition to the accounts receivables sold, an amount of $436 million of the SPV’s accounts receivables is pledged to PNC by the SPV as a seller guarantee, and is included under “Accounts receivables, net”, in our consolidated balance sheet as of December 31,2022. In the fourth quarter of 2022, Teva received proceeds of $820 million under the AR facility, which are included in cash from operating activities in the Consolidated Statements of Cash Flows for the year ended December 31, 2022.

As of December 31, 2022, our debt was $21,212 million, compared to $23,043 million as of December 31, 2021. This decrease was mainly due to $1,369 million of senior notes repaid at maturity and $484 million of exchange rate fluctuations. The portion of total debt classified as short-term as of December 31, 2022 was 10%, compared to 6% as of December 31, 2021, mainly due to repayment of debt, partially offset by a reclassification of upcoming maturities in 2022. Our average debt maturity was approximately 5.8 years as of December 31, 2022, compared to 6.4 years as of December 31, 2021.

Fourth Quarter 2022 Consolidated Results

Revenues in the fourth quarter of 2022 were $3,884 million, a decrease of 5% in U.S. dollars or an increase of 1% in local currency terms, compared to the fourth quarter of 2021. This increase was mainly due to higher revenues from Anda, generic products in our Europe segment, AUSTEDO and AJOVY, partially offset by lower revenues from generic products and certain respiratory products in our North America segment as well as COPAXONE.

Exchange rate differences between the fourth quarter of 2022 and the fourth quarter of 2021, including hedging effects, negatively impacted revenues by $270 million and operating income by $132 million. Non-GAAP operating income was negatively impacted by $135 million.

Gross profit was $1,770 million in the fourth quarter of 2022, a decrease of 14% compared to the fourth quarter of 2021. Gross profit margin was 45.6% in the fourth quarter of 2022, compared to 50.0% in the fourth quarter of 2021. Non-GAAPgross profit was $2,105 million in the fourth quarter of 2022, a decrease of 9% compared to the fourth quarter of 2021. Non-GAAPgross profit margin was 54.2% in the fourth quarter of 2022, compared to 56.1% in the fourth quarter of 2021. The decrease in gross profit margin in the fourth quarter of 2022 resulted mainly from an increase in revenues with lower profitability from Anda in our North America segment, partially offset by higher revenues from AUSTEDO in our North America segment and a favorable mix of generic products in our Europe segment.

Research and Development (R&D) expenses in the fourth quarter of 2022 were $210 million, a decrease of 14% compared to the fourth quarter of 2021. The decrease in R&D expenses in the fourth quarter of 2022 was mainly due to a decrease in various generics projects as well as in immunology (in the respiratory therapeutic area), partially offset by higher R&D expenses related to our biosimilar products pipeline.

Selling and Marketing (S&M) expenses in the fourth quarter of 2022 were $549 million, a decrease of 13% compared to the fourth quarter of 2021.

General and Administrative (G&A) expenses in the fourth quarter of 2022 were $289 million, an increase of 4% compared to the fourth quarter of 2021.

Other income in the fourth quarter of 2022 was $19 million, compared to $26 million in the fourth quarter of 2021.

Operating loss in the fourth quarter of 2022 was $855 million, compared to operating income of $78 million in the fourth quarter of 2021. This decrease was mainly due to goodwill impairment charges recorded in the fourth quarter of 2022, partially offset by lower legal settlements and loss contingencies. Operating loss as a percentage of revenues was 22.0% in the fourth quarter of 2022, compared to operating income as a percentage of revenues of 1.9% in the fourth quarter of 2021. The decrease in operating margin was mainly due to the effect of goodwill impairment charges as a percentage of revenues, partially offset by lower legal settlements and loss contingencies as a percentage of revenues.

Non-GAAP operating income in the fourth quarter of 2022 was $1,130 million or 29.1% of revenues compared to $1,248 million or 30.4% of revenues in the fourth quarter of 2021. Non-GAAP operating margin in the fourth quarter of 2022 was mainly affected by lower gross profit margin, as discussed above, partially offset by lower operating expenses as a percentage of revenues.

Adjusted EBITDA was $1,240 million in the fourth quarter of 2022, a decrease of 10%, compared to $1,373 million in the fourth quarter of 2021.

Financial expenses, net in the fourth quarter of 2022 were $245 million, compared to $253 million in the fourth quarter of 2021. Financial expenses, net in the fourth quarter of 2022 and 2021, were mainly comprised of interest expenses of $237 million and $225 million, respectively.

In the fourth quarter of 2022, we recognized a tax expense of $154 million on a pre-tax loss of $1,100 million, mainly due to goodwill impairment charges that did not have a corresponding tax effect. In the fourth quarter of 2021, we recognized a tax benefit of $24 million on pre-tax loss of $175 million.

Non-GAAP tax rate in the fourth quarter of 2022 was 11%, compared to 15% in the fourth quarter of 2021. Our non-GAAP tax rate in the fourth quarter of 2022 was mainly affected by the mix of products we sold, interest expense disallowances and adjustments to valuation allowances on deferred tax assets.

Net loss attributable to Teva and diluted loss per share in the fourth quarter of 2022 were $1,221 million and $1.10, respectively, compared to $159 million and $0.14, respectively, in the fourth quarter of 2021. Non-GAAP net income attributable to Teva and non-GAAP diluted earnings per share in the fourth quarter of 2022 were $791 million and $0.71, respectively, compared to $854 million and $0.77, respectively, in the fourth quarter of 2021.

Non-GAAP information: net non-GAAP adjustments in the fourth quarter of 2022 were $2,012 million. Non-GAAP net income attributable to Teva and non-GAAP diluted EPS for the fourth quarter were adjusted to exclude the following items:

Amortization of purchased intangible assets of $156 million, of which $136 million is included in cost of sales and the remaining $20 million in S&M expenses;

Legal settlements and loss contingencies of $34 million;

Goodwill impairment charges of $1,300 million;

Impairment of long-lived assets of $145 million;

Restructuring expenses of $30 million;

Costs related to regulatory actions taken in facilities of $1 million;

Equity compensation expenses of $36 million;

Contingent consideration expenses of $63 million;

Gain on sale of business in an amount of $15 million;

Accelerated depreciation of $39 million;

Financial expenses of $14 million;

Items attributable to non-controlling interests in an amount of $43 million;

Other non-GAAP items of $196 million; and

Corresponding tax effects and unusual tax items of $56 million.

We believe that excluding such items facilitates investors' understanding of our business. Commencing the first quarter of 2022, we no longer exclude IPR&D acquired in development arrangements from our non-GAAP financial measures. In our comparable non-GAAP financial measures for the fourth quarter of 2021, we excluded $10 million IPR&D acquired in development arrangements. We are not recasting the non-GAAP presentation for the fourth quarter of 2021 since the adjustment is not significant. We have made this change to our presentation of non-GAAP financial measures to improve comparability of our non-GAAP presentation to those of other companies in the pharmaceutical industry that made a similar change to their presentations beginning in the first quarter of 2022.

For further information, see the tables below for a reconciliation of the U.S. GAAP results to the adjusted non-GAAP figures and the information under “Non-GAAP Financial Measures.” Investors should consider non-GAAP financial measures in addition to, and not as replacement for, or superior to, measures of financial performance prepared in accordance with GAAP.

Cash flow generated from operating activities during the fourth quarter of 2022 was $973 million, compared to $456 million in the fourth quarter of 2021. The increase resulted mainly from the sale of accounts receivables under our U.S. securitization facility entered into in November 2022, partially offset by changes in working capital items, primarily an increase in accounts receivables, net of SR&A due to timing of sales cycle in the fourth quarter of 2022.

Segment Results for the Fourth Quarter of 2022

North America Segment

Our North America segment includes the United States and Canada.

The following table presents revenues, expenses and profit for our North America segment for the three months ended December 31, 2022 and 2021:

Three months ended December 31,

2022

2021

(U.S. $ in millions / % of Segment Revenues)

Revenues

2,002

100%

2,003

100%

Gross profit

1,085

54.2%

1,145

57.2%

R&D expenses

131

6.6%

151

7.5%

S&M expenses

209

10.4%

255

12.7%

G&A expenses

113

5.7%

4.4%

Other income

(2)

(17)

(0.8%)

Segment profit*

633

31.6%

668

33.4%

*Segment profit does not include amortization and certain other items.

§ Represents an amount less than $0.5 million or 0.5%, as applicable.

Revenues from our North America segment in the fourth quarter of 2022 were $2,002 million, flat, compared to the fourth quarter of 2021, mainly due to a decline in revenues from generic products, COPAXONE and BENDEKA and TREANDA, offset by higher revenues from our innovative products - AUSTEDO and AJOVY, and Anda.

Revenues in the United States, our largest market, were $1,912 million in the fourth quarter of 2022, an increase of $35 million, or 2%, compared to the fourth quarter of 2021.

Revenues by Major Products and Activities

The following table presents revenues for our North America segment by major products and activities for the three months ended December 31, 2022 and 2021:

Three months ended

December 31,

Percentage

Change

2022

2021

2022-2021

(U.S. $ in millions)

Generic products

818

905

(10%)

AJOVY

41%

AUSTEDO

344

282

22%

BENDEKA and TREANDA

(20%)

COPAXONE

101

129

(22%)

Anda

450

355

27%

Other*

138

186

(26%)

Total

2,002

2,003

* Other revenues in the fourth quarter of 2022 decreased mainly due to reduction

in sales of certain innovative respiratory products. On October 1, 2022,

we discontinued marketing ProAir® HFA.

Generic products revenues in our North America segment in the fourth quarter of 2022 decreased by 10% to $818 million, compared to the fourth quarter of 2021, mainly due to increased competition to parts of our portfolio as well as supply disruptions including the closure of the Irvine, CA site.

In the fourth quarter of 2022, our total prescriptions were approximately 80 million representing 8.3% of total U.S. generic prescriptions according to IQVIA data.

AJOVY revenues in our North America segment in the fourth quarter of 2022 were $75 million compared to $53 million in the fourth quarter of 2021. This increase was mainly due to growth in volume and favorable net pricing.

AUSTEDO revenues in our North America segment in the fourth quarter of 2022 were $344 million, compared to $282 million in the fourth quarter of 2021. This increase was mainly due to growth in volume.

BENDEKA and TREANDA combined revenues in our North America segment in the fourth quarter of 2022 decreased by 20% to $75 million, compared to the fourth quarter of 2021, mainly due to the availability of alternative therapies and intense competition. In December 2022, the orphan drug exclusivity that had attached to bendamustine products expired. To-date we are aware of one generic TREANDA product on the market.

COPAXONE revenues in our North America segment in the fourth quarter of 2022 decreased by 22% to $101 million, compared to the fourth quarter of 2021, mainly due to generic competition in the United States and a decrease in glatiramer acetate market share due to availability of alternative biologic therapies.

Anda revenues in our North America segment in the fourth quarter of 2022 increased by 27% to $450 million, compared to the fourth quarter of 2021, mainly due to higher demand.

North America Gross Profit

Gross profit from our North America segment in the fourth quarter of 2022 was $1,085 million, a decrease of 5% compared to the fourth quarter of 2021, mainly due to lower revenues as discussed above. Gross profit margin for our North America segment in the fourth quarter of 2022 decreased to 54.2%, compared to 57.2% in the fourth quarter of 2021. This decrease was mainly due to an unfavorable mix of products.

North America Profit

Profit from our North America segment consists of gross profit less R&D expenses, S&M expenses, G&A expenses and any other income related to this segment. Segment profit does not include amortization and certain other items.

Profit from our North America segment in the fourth quarter of 2022 was $633 million, a decrease of 5% compared to $668 million in the fourth quarter of 2021. Profit decreased mainly due to lower revenues, partially offset by lower operating expenses.

Europe Segment

Our Europe segment includes the European Union, the United Kingdom and certain other European countries.

The following table presents revenues, expenses and profit for our Europe segment for the three months ended December 31, 2022 and 2021:

Three months ended December 31,

2022

2021

(U.S. $ in millions / % of Segment Revenues)

Revenues

1,129

100%

1,268

100%

Gross profit

669

59.3%

760

59.9%

R&D expenses

4.9%

4.8%

S&M expenses

187

16.6%

218

17.2%

G&A expenses

5.6%

5.0%

Other income

(2)

Segment profit*

366

32.4%

420

33.1%

* Segment profit does not include amortization and certain other items.

§ Represents an amount less than $0.5 million or 0.5%, as applicable.

Revenues from our Europe segment in the fourth quarter of 2022 were $1,129 million, a decrease of $139 million, or 11%, compared to the fourth quarter of 2021. In local currency terms, revenues increased by 4%, mainly due to higher demand for generic products resulting from new product launches as well as higher revenues from AJOVY, partially offset by lower revenues from COPAXONE and certain other respiratory products.

In the fourth quarter of 2022, revenues were negatively impacted by exchange rate fluctuations of $193 million, including hedging effects, compared to the fourth quarter of 2021. Revenues in the fourth quarter of 2022 included $46 million from a negative hedging impact, which are included in “Other” in the table below.

Revenues by Major Products and Activities

The following table presents revenues for our Europe segment by major products and activities for the three months ended December 31, 2022 and 2021:

Three months ended

December 31,

Percentage

C hange

2022

2021

2022-2021

(U.S. $ in millions)

Generic products

914

932

(2%)

AJOVY

19%

COPAXONE

(35%)

Respiratory products

(19%)

Other

119

(63%)

Total

1,129

1,268

(11%)

Generic products revenues (including OTC and biosimilar products) in our Europe segment in the fourth quarter of 2022, decreased by 2% to $914 million, compared to the fourth quarter of 2021. In local currency terms, revenues increased by 10%, mainly due to higher demand for generic products resulting from new product launches.

AJOVY revenues in our Europe segment in the fourth quarter of 2022 increased by 19% to $35 million, compared the fourth quarter of 2021. In local currency terms, revenues increased by 34%, mainly due to launches and reimbursements in additional European countries and growth in existing countries.

COPAXONE revenues in our Europe segment in the fourth quarter of 2022 decreased by 35% to $61 million, compared to the fourth quarter of 2021. In local currency terms, revenues decreased by 27% due to price reductions and a decline in volume resulting from competing glatiramer acetate products and availability of alternative therapies.

Respiratory products revenues in our Europe segment in the fourth quarter of 2022 decreased by 19% to $75 million, compared to the fourth quarter of 2021. In local currency terms, revenues decreased by 8% mainly due to net price reductions and lower volumes.

Europe Gross Profit

Gross profit from our Europe segment in the fourth quarter of 2022 was $669 million, a decrease of 12% compared to $760 million in the fourth quarter of 2021. This decrease was mainly due to exchange rate fluctuations.

Gross profit margin for our Europe segment in the fourth quarter of 2022 decreased to 59.3%, compared to 59.9% in the fourth quarter of 2021. This decrease was mainly due to the negative impact of hedging activities, as discussed above.

Europe Profit

Profit from our Europe segment consists of gross profit less R&D expenses, S&M expenses, G&A expenses and any other income related to this segment. Segment profit does not include amortization and certain other items.

Profit from our Europe segment in the fourth quarter of 2022 was $366 million, a decrease of 13% compared to $420 million in the fourth quarter of 2021. This decrease was mainly due to lower gross profit as discussed above, partially offset by lower operating expenses.

International Markets Segment

Our International Markets segment includes all countries other than those in our North America and Europe segments.

The following table presents revenues, expenses and profit for our International Markets segment for the three months ended December 31, 2022 and 2021:

Three months ended December 31,

2022

2021

(U.S. $ in millions / % of Segment Revenues)

Revenues

482

100%

527

100%

Gross profit

253

52.6%

292

55.3%

R&D expenses

3.7%

3.2%

S&M expenses

112

23.2%

114

21.6%

G&A expenses

6.3%

5.7%

Other income

Segment profit*

19.4%

131

24.8%

* Segment profit does not include amortization and certain other items.

§ Represents an amount less than $0.5 million or 0.5%, as applicable.

Revenues from our International Markets segment in the fourth quarter of 2022 were $482 million, a decrease of $45 million, or 9%, compared to the fourth quarter of 2021. In local currency terms, revenues increased by 3% compared to the fourth quarter of 2021, mainly due to higher revenues in most markets.

Revenues by Major Products and Activities

The following table presents revenues for our International Markets segment by major products and activities for the three months ended December 31, 2022 and 2021:

Three months ended

December 31,

Percentage

Change

2022

2021

2022-2021

(U.S. $ in millions)

Generic products

411

438

(6%)

AJOVY

188%

COPAXONE

(19%)

Other

(34%)

Total

482

527

(9%)

Generic products revenues in our International Markets segment, including OTC products, were $411 million in the fourth quarter of 2022, a decrease of 6% compared to the fourth quarter of 2021. In local currency terms, revenues increased by 3%, due to higher revenues in most markets.

AJOVY was launched in certain markets in our International Markets segment, including in Japan during the third quarter of 2021. We are moving forward with plans to launch AJOVY in other markets. AJOVY revenues in our International Markets segment in the fourth quarter of 2022 were $13 million, compared to $4 million in the fourth quarter of 2021.

COPAXONE revenues in our International Markets segment in the fourth quarter of 2022 decreased by 19% to $7 million, compared to the fourth quarter of 2021. In local currency terms, revenues increased by 1%.

International Markets Gross Profit

Gross profit from our International Markets segment in the fourth quarter of 2022 was $253 million, a decrease of 13% compared to $292 million in the fourth quarter of 2021. Gross profit margin for our International Markets segment in the fourth quarter of 2022 decreased to 52.6%, compared to 55.3% in the fourth quarter of 2021, mainly due to foreign exchange rate fluctuations and a different portfolio mix.

International Markets Profit

Profit from our International Markets segment consists of gross profit less R&D expenses, S&M expenses, G&A expenses and any other income related to this segment. Segment profit does not include amortization and certain other items.

Profit from our International Markets segment in the fourth quarter of 2022 was $93 million, compared to $131 million in the fourth quarter of 2021. This decrease was mainly due to lower gross profit.

Other Activities

We have other sources of revenues, primarily the sale of active pharmaceutical ingredients ("APIs") to third parties, certain contract manufacturing services and an out-licensing platform offering a portfolio of products to other pharmaceutical companies through our affiliate Medis. Our other activities are not included in our North America, Europe or International Markets segments.

Our revenues from other activities in the fourth quarter of 2022 were $272 million, a decrease of 10% compared to the fourth quarter of 2021. In local currency terms revenues decreased by 7%.

API sales to third parties in the fourth quarter of 2022 were $168 million, a decrease of 18% in both U.S. dollars and local currency terms, compared to the fourth quarter of 2021.

Outlook for 2023 Non-GAAP Results

$ billions, except diluted EPS or as noted

2023 Outlook

2022 Actual

Revenues*

14.8 – 15.4

14.9

COPAXONE ($m)*

~500

691

AUSTEDO ($m)*

~1,200

971

AJOVY ($m)*

~400

377

Operating Income

4.0 – 4.4

4.1

Adjusted EBITDA

4.5 – 4.9

4.6

Diluted EPS ($)

2.25 – 2.55

1,123 million shares

2.52

1,115 million shares

Free Cash Flow**

1.7 - 2.1

2.2

CAPEX*

0.5

Tax Rate

14% – 17%

11.7%

Foreign Exchange

Volatile swings in FX can negatively impact revenue and income

* Revenues and CAPEX presented on a GAAP basis.

** Free Cash Flow includes cash flow generated from operating activities net of capital expenditures and deferred purchase price cash component collected for securitized trade receivables

Annual Report on Form 10-K

Teva's Annual Report on Form 10-K for the year ended December 31, 2022, which will be filed with the SEC, will include a complete analysis of the financial results for 2022 and will be available on Teva’s website: http://ir.tevapharm.com, as well as on the SEC’s website: http://www.sec.gov.

Conference Call

Teva will host a conference call and live webcast along with a slide presentation on Wednesday, February 8, 2023 at 8:00 a.m. ET to discuss its fourth quarter and annual 2022 results and overall business environment. A question and answer session will follow.

In order to participate, please register in advance here to obtain a local or toll-free phone number and your personal pin. A live webcast of the call will be available on Teva's website at: https://ir.tevapharm.com/Events-and-Presentations. Following the conclusion of the call, a replay of the webcast will be available within 24 hours on Teva's website.

About Teva

Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA) has been developing and producing medicines to improve people’s lives for more than a century. We are a global leader in generic and innovative medicines with a portfolio consisting of over 3,500 products in nearly every therapeutic area. Around 200 million people around the world take a Teva medicine every day, and are served by one of the largest and most complex supply chains in the pharmaceutical industry. Along with our established presence in generics, we have significant innovative medicines research and operations supporting our growing portfolio of innovative medicines and biopharmaceutical products. Learn more at www.tevapharm.com.

Some amounts in this press release may not add up due to rounding. All percentages have been calculated using unrounded amounts.

Non-GAAP Financial Measures

This press release contains certain financial information that differs from what is reported under accounting principles generally accepted in the United States ("GAAP"). These non-GAAP financial measures, including, but not limited to, non-GAAP operating income, non-GAAP operating margin, non-GAAP gross profit, non-GAAP gross profit margin, Adjusted EBITDA, free cash flow, non-GAAP tax rate, non-GAAP net income (loss) attributable to Teva and non-GAAP diluted EPS, are presented in order to facilitate investors' understanding of our business. We utilize certain non-GAAP financial measures to evaluate performance, in conjunction with other performance metrics. The following are examples of how we utilize the non-GAAP measures: our management and board of directors use the non-GAAP measures to evaluate our operational performance, to compare against work plans and budgets, and ultimately to evaluate the performance of management; our annual budgets are prepared on a non-GAAP basis; and senior management’s annual compensation is derived, in part, using these non-GAAP measures. See the attached tables for a reconciliation of the GAAP results to the adjusted non-GAAP measures. Investors should consider non-GAAP financial measures in addition to, and not as replacements for, or superior to, measures of financial performance prepared in accordance with GAAP. We are not providing forward looking guidance for GAAP reported financial measures or a quantitative reconciliation of forward-looking non-GAAP financial measures to the most directly comparable GAAP measure because we are unable to predict with reasonable certainty the ultimate outcome of certain significant items including, but not limited to, the amortization of purchased intangible assets, legal settlements and loss contingencies, impairment of long-lived assets and goodwill impairment, without unreasonable effort. These items are uncertain, depend on various factors, and could be material to our results computed in accordance with GAAP.

Cautionary Note Regarding Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, which are based on management’s current beliefs and expectations and are subject to substantial risks and uncertainties, both known and unknown, that could cause our future results, performance or achievements to differ significantly from that expressed or implied by such forward-looking statements. You can identify these forward-looking statements by the use of words such as “should,” “expect,” “anticipate,” “estimate,” “target,” “may,” “project,” “guidance,” “intend,” “plan,” “believe” and other words and terms of similar meaning and expression in connection with any discussion of future operating or financial performance. Important factors that could cause or contribute to such differences include risks relating to:

our ability to successfully compete in the marketplace, including: that we are substantially dependent on our generic products; concentration of our customer base and commercial alliances among our customers; delays in launches of new generic products; the increase in the number of competitors targeting generic opportunities and seeking U.S. market exclusivity for generic versions of significant products; our ability to develop and commercialize biopharmaceutical products; competition for our innovative medicines, including AUSTEDO, AJOVY and COPAXONE; our ability to achieve expected results from investments in our product pipeline; our ability to develop and commercialize additional pharmaceutical products; and the effectiveness of our patents and other measures to protect our intellectual property rights.

our substantial indebtedness, which may limit our ability to incur additional indebtedness, engage in additional transactions or make new investments, may result in a further downgrade of our credit ratings; and our inability to raise debt or borrow funds in amounts or on terms that are favorable to us;

our business and operations in general, including: the impact of global economic conditions and other macroeconomic developments and the governmental and societal responses thereto; the widespread outbreak of an illness or any other communicable disease, or any other public health crisis; effectiveness of our optimization efforts; our ability to attract, hire, integrate and retain highly skilled personnel; manufacturing or quality control problems; interruptions in our supply chain; disruptions of information technology systems; breaches of our data security; variations in intellectual property laws; challenges associated with conducting business globally, including political or economic instability, major hostilities or terrorism; costs and delays resulting from the extensive pharmaceutical regulation to which we are subject.

the effects of reforms in healthcare regulation and reductions in pharmaceutical pricing, reimbursement and coverage; significant sales to a limited number of customers; our ability to successfully bid for suitable acquisition targets or licensing opportunities, or to consummate and integrate acquisitions; and our prospects and opportunities for growth if we sell assets;

compliance, regulatory and litigation matters, including: failure to comply with complex legal and regulatory environments; increased legal and regulatory action in connection with public concern over the abuse of opioid medications and any delay in our ability to obtain sufficient participation of plaintiffs for the nationwide settlement of our opioid-related litigation in the United States; scrutiny from competition and pricing authorities around the world, including our ability to successfully defend against the U.S. Department of Justice criminal charges of Sherman Act violations; potential liability for intellectual property right infringement; product liability claims; failure to comply with complex Medicare and Medicaid reporting and payment obligations; compliance with anti-corruption, sanctions and trade control laws; environmental risks; and the impact of ESG issues;

other financial and economic risks, including: our exposure to currency fluctuations and restrictions as well as credit risks; potential impairments of our long-lived assets; the impact of geopolitical conflicts including the ongoing conflict between Russia and Ukraine; potential significant increases in tax liabilities; and the effect on our overall effective tax rate of the termination or expiration of governmental programs or tax benefits, or of a change in our business;

and other factors discussed in this press release and in our Annual Report on Form 10-K for the year ended December 31, 2022, including in the sections captioned "Risk Factors” and “Forward Looking Statements.” Forward-looking statements speak only as of the date on which they are made, and we assume no obligation to update or revise any forward-looking statements or other information contained herein, whether as a result of new information, future events or otherwise. You are cautioned not to put undue reliance on these forward-looking statements.

Consolidated Statements of Income

(U.S. dollars in millions, except share and per share data)

Three months ended

Year ended

December 31,

2022

2021

2022

2021

(Unaudited)

(Audited)

Net revenues

3,884

4,100

14,925

15,878

Cost of sales

2,113

2,049

7,952

8,284

Gross profit

1,770

2,050

6,973

7,594

Research and development expenses, net

210

244

838

967

Selling and marketing expenses

549

632

2,265

2,429

General and administrative expenses

289

276

1,180

1,099

Intangible assets impairment

132

129

355

424

Goodwill impairment

1,300

2,045

Other asset impairments, restructuring and other items

132

113

414

341

Legal settlements and loss contingencies

604

2,082

717

Other income

(19)

(26)

(107)

(98)

Operating income (loss)

(855)

(2,099)

1,716

Financial expenses – net

245

253

966

1,058

Income (loss) before income taxes

(1,100)

(175)

(3,065)

658

Income taxes (benefit)

154

(24)

(638)

211

Share in (profits) losses of associated companies, net

(21)

(9)

Net income (loss)

(1,254)

(151)

(2,406)

456

Net income (loss) attributable to non-controlling interests

(32)

(53)

Net income (loss) attributable to Teva

(1,221)

(159)

(2,353)

417

Earnings (loss) per share attributable to Teva:

Basic ($)

(1.10)

(0.14)

(2.12)

0.38

Diluted ($)

(1.10)

(0.14)

(2.12)

0.38

Weighted average number of shares (in millions):

Basic

1,111

1,103

1,110

1,102

Diluted

1,111

1,103

1,110

1,107

Non-GAAP net income attributable to Teva for diluted earnings per share:*

791

854

2,812

2,855

Non-GAAP earnings per share attributable to Teva:*

Diluted ($)

0.71

0.77

2.52

2.58

Non-GAAP average number of shares (in millions):

Diluted

1,121

1,108

1,115

1,107

* See reconciliation attached.

Condensed Consolidated Balance Sheets

(U.S. dollars in millions)

(Audited)

December 31,

2022

2021

ASSETS

Current assets:

Cash and cash equivalents

2,801

2,165

Accounts receivables, net of allowance for credit losses of $91 million and

$90 million as of December 31, 2022 and December 31, 2021

3,696

4,529

Inventories

3,833

3,818

Prepaid expenses

1,162

1,075

Other current assets

549

965

Assets held for sale

Total current assets

12,051

12,573

Deferred income taxes

1,453

596

Other non-current assets

441

515

Property, plant and equipment, net

5,739

5,982

Operating lease right-of-use assets

419

495

Identifiable intangible assets, net

6,270

7,466

Goodwill

17,633

20,040

Total assets

44,006

47,666

LIABILITIES & EQUITY

Current liabilities:

Short-term debt

2,109

1,426

Sales reserves and allowances

3,750

4,241

Trade payables

1,887

1,686

Employee-related obligations

566

563

Accrued expenses

2,151

2,208

Other current liabilities

1,005

903

Total current liabilities

11,469

11,027

Long-term liabilities:

Deferred income taxes

548

784

Other taxes and long-term liabilities

3,847

2,578

Senior notes and loans

19,103

21,617

Operating lease liabilities

349

416

Total long-term liabilities

23,846

25,395

Equity:

Teva shareholders’ equity:

7,897

10,278

Non-controlling interests

794

966

Total equity

8,691

11,244

Total liabilities and equity

44,006

47,666

TEVA PHARMACEUTICAL INDUSTRIES LIMITED

CONSOLIDATED STATEMENTS OF CASH FLOWS

(U.S. dollars in millions)

Year ended

Three months ended

December 31,

2022

2021

2022

2021

Operating activities:

(Audited)

(Unaudited)

Net income (loss)

(2,406)

456

(1,254)

(152)

Adjustments to reconcile net income (loss) to net cash provided by operations:

Impairment of goodwill, long-lived assets and assets held for sale

2,447

584

1,445

183

Depreciation and amortization

1,308

1,330

306

320

Net change in operating assets and liabilities

1,257

(1,701)

250

180

Deferred income taxes — net and uncertain tax positions

(1,059)

(120)

155

(133)

Stock-based compensation

124

119

Other items

(91)

Research and development in process

Net loss (gain) from investments and from sale of business and long lived assets

104

(5)

Net cash provided by (used in) operating activities

1,590

798

973

456

Investing activities:

Beneficial interest collected in exchange for securitized trade receivables

1,140

1,648

286

370

Proceeds from sale of business and long lived assets

311

Purchases of property, plant and equipment

(548)

(562)

(142)

(153)

Purchases of investments and other assets

(1)

(47)

(11)

Proceeds from sale of investments

172

Other investing activities

(2)

Acquisitions of businesses, net of cash acquired

(7)

Net cash provided by (used in) investing activities

656

1,523

170

246

Financing activities:

Repayment of senior notes and loans and other long term liabilities

(1,369)

(6,649)

(713)

(5,174)

Proceeds from senior notes, net of issuance costs

4,974

Proceeds from short term debt

700

200

Repayment of short term debt

(700)

(500)

Redemption of convertible debentures

(491)

Other financing activities

(118)

(6)

(1)

Net cash provided by (used in) financing activities

(1,487)

(2,172)

(713)

(501)

Translation adjustment on cash and cash equivalents

(123)

(128)

146

(48)

Net change in cash, cash equivalents and restricted cash

636

576

153

Balance of cash, cash equivalents and restricted cash at beginning of year

2,198

2,177

2,258

2,045

Balance of cash, cash equivalents and restricted cash at end of year

2,834

2,198

2,834

2,198

Reconciliation of cash, cash equivalents and restricted cash

reported in the consolidated Balance sheets:

Cash and cash equivalents

2,801

2,165

2,801

2,165

Restricted cash included in other current assets

Total cash, cash equivalents and restricted cash shown

in the statements of cash flows

2,834

2,198

2,834

2,198

Reconciliation of gross profit to Non-GAAP gross profit

Three months ended

Year ended

December 31,

($ in millions)

2022

2021

2022

2021

Gross profit

($)

1,770

2,050

($)

6,973

7,594

Gross profit margin

45.6%

50.0%

46.7%

47.8%

Increase (decrease) for excluded items:

Amortization of purchased intangible assets

136

165

649

702

Costs related to regulatory actions taken in facilities

Equity compensation

Accelerated Depreciation

115

Other non-GAAP items*

154

290

252

Non-GAAP gross profit

($)

2,105

2,301

($)

8,056

8,612

Non-GAAP gross profit margin**

54.2%

56.1%

54.0%

54.2%

* Other non-GAAP items include other exceptional items that we believe are sufficiently large

that their exclusion is important to facilitate an understanding of trends in our financial results,

such as certain accelerated depreciation expenses and inventory write offs, primarily related to

the rationalization of our plants and other unusual events.

** Non-GAAP gross profit margin is non-GAAP gross profit as a percentage of revenue.

Reconciliation of operating income (loss) to Non-GAAP operating income (loss)

Three months ended

Year ended,

December 31,

($ in millions)

2022

2021

2022

2021

Operating income (loss)

($)

(855)

($)

(2,099)

1,716

Operating margin

(22%)

1.9%

(14.1%)

10.8%

Increase (decrease) for excluded items:

Amortization of purchased intangible assets

156

188

732

802

Legal settlements and loss contingencies

604

2,082

717

Goodwill impairment

1,300

2,045

Impairment of long-lived assets

145

183

402

584

Other R&D expenses

Restructuring costs

146

133

Costs related to regulatory actions taken in facilities

Equity compensation

124

118

Contingent consideration

163

Gain on sale of business

(15)

(7)

(47)

(51)

Accelerated depreciation

117

Other non-GAAP items*

196

465

318

Non-GAAP operating income (loss)

($)

1,130

1,248

($)

4,139

4,401

Non-GAAP operating margin**

29.1%

30.4%

27.7%

* Other non-GAAP items include other exceptional items that we believe are sufficiently large that their exclusion

is important to facilitate an understanding of trends in our financial results, such as certain accelerated depreciation

expenses and inventory write offs, primarily related to the rationalization of our plants, material litigation fees and

other unusual events.

** Non-GAAP operating margin is Non-GAAP operating income as a percentage of revenues.

Reconciliation of net income (loss) attributable to Teva

to Non-GAAP net income (loss) attributable to Teva

Three months ended

Year ended

December 31,

($ in millions except per share amounts)

2022

2021

2022

2021

Net income (loss) attributable to Teva

($)

(1,221)

(159)

($)

(2,353)

417

Increase (decrease) for excluded items:

Amortization of purchased intangible assets

156

188

732

802

Legal settlements and loss contingencies

604

2,082

717

Goodwill impairment

1,300

2,045

Impairment of long-lived assets

145

183

402

584

Other R&D expenses

Restructuring expenses

146

133

Costs related to regulatory actions taken in facilities

Equity compensation expenses

124

118

Contingent consideration expenses

163

Gain on sale of business

(15)

(7)

(47)

(51)

Accelerated depreciation

117

Financial expenses

128

Share in profits (losses) of associated companies - net

(22)

(1)

Items attributable to non-controlling interests

(43)

(5)

(96)

(15)

Other non-GAAP items*

196

465

318

Corresponding tax effects and unusual tax items

(178)

(1,016)

(360)

Non-GAAP net income attributable to Teva

($)

791

854

($)

2,812

2,855

Non-GAAP tax rate**

11.0%

15.0%

11.7%

16.4%

GAAP diluted earnings (loss) per share attributable to Teva

($)

(1.10)

(0.14)

($)

(2.12)

0.38

EPS difference***

1.81

0.91

4.64

2.20

Non-GAAP Diluted EPS attributable to Teva***

($)

0.71

0.77

($)

2.52

2.58

Non-GAAP average number of shares (in millions)***

1,121

1,108

1,115

1,107

* Other non-GAAP items include other exceptional items that we believe are sufficiently large that their exclusion is important

to facilitate an understanding of trends in our financial results, such as certain accelerated depreciation expenses and

inventory write offs, primarily related to the rationalization of our plants, material litigation fees and other unusual events.

** Non-GAAP tax rate is tax expenses excluding the impact of non-GAAP tax adjustments presented above as a percentage

of income (loss) before income taxes excluding the impact of non-GAAP adjustments presented above.

***EPS difference and diluted non-GAAP EPS are calculated by dividing our non-GAAP net income attributable to Teva

by our non-GAAP diluted weighted average number of shares.

Reconciliation of net income (loss) to adjusted EBITDA

Three months ended

Year ended

December 31,

($ in millions)

2022

2021

2022

2021

Net income (loss)

($)

(1,254)

(151)

($)

(2,406)

456

Increase (decrease) for excluded items:

Financial expenses

245

253

966

1,058

Income taxes

154

(24)

(638)

211

Share in losses of associated companies- net

(21)

(9)

Depreciation

150

132

576

528

Amortization

156

188

732

802

EBITDA

($)

(550)

397

($)

(791)

3,046

Legal settlements and loss contingencies

604

2,082

717

Goodwill impairment

1,300

2,045

Impairment of long lived assets

145

183

402

584

Other R&D expenses

Restructuring costs

146

133

Costs related to regulatory actions taken in facilities

Equity compensation

124

118

Contingent consideration

163

Gain on sale of business

(15)

(7)

(47)

(51)

Other non-GAAP items *

196

465

318

Adjusted EBITDA

($)

1,240

1,373

($)

4,598

4,911

* Other non-GAAP items include other exceptional items that we believe are sufficiently large that their exclusion is important to

facilitate an understanding of trends in our financial results, such as certain accelerated depreciation expenses and inventory

write offs, primarily related to the rationalization of our plants, material litigation fees and other unusual events.

Segment Information

North America

Europe

International Markets

Three months ended

December 31,

Three months ended

December 31,

Three months ended

December 31,

2022

2021

2022

2021

2022

2021

(U.S. $ in millions)

Revenues

2,002

2,003

1,129

1,268

482

527

Gross profit

1,085

1,145

669

760

253

292

R&D expenses

131

151

S&M expenses

209

255

187

218

112

114

G&A expenses

113

Other (income) expense

(2)

(17)

(2)

Segment profit

633

668

366

420

131

Segment Information

North America

Europe

International Markets

Year ended December 31,

2022

2021

2022

2021

2022

2021

(U.S. $ in millions)

Revenues

7,452

7,809

4,525

4,886

1,903

2,032

Gross profit

3,926

4,226

2,700

2,823

1,033

1,118

R&D expenses

532

618

213

244

S&M expenses

941

988

748

846

405

417

G&A expenses

474

427

246

244

119

109

Other (income) expense

(15)

(31)

(3)

(5)

(43)

(5)

Segment profit

1,993

2,224

1,496

1,494

479

529

Reconciliation of our segment profit

to consolidated income before income taxes

Three months ended

December 31,

2022

2021

(U.S.$ in millions)

North America profit

633

668

Europe profit

366

420

International Markets profit

131

Total segment profit

1,093

1,219

Profit (loss) of other activities

Total segment profit

1,130

1,248

Amounts not allocated to segments:

Amortization

156

188

Other asset impairments, restructuring and other items

132

113

Goodwill impairment

1,300

Intangible asset impairments

132

129

Legal settlements and loss contingencies

604

Other unallocated amounts

231

136

Consolidated operating income (loss)

(855)

Financial expenses - net

245

253

Consolidated income (loss) before income taxes

(1,100)

(175)

Reconciliation of our segment profit

to consolidated income before income taxes

Year ended

December 31,

2022

2021

(U.S.$ in millions)

North America profit

1,993

2,224

Europe profit

1,496

1,494

International Markets profit

479

529

Total segment profit

3,968

4,246

Profit (loss) of other activities

172

154

Total segment profit

4,140

4,401

Amounts not allocated to segments:

Amortization

732

802

Other asset impairments, restructuring and other items

414

341

Goodwill impairment

2,045

Intangible asset impairments

355

424

Legal settlements and loss contingencies

2,082

717

Other unallocated amounts

610

402

Consolidated operating income (loss)

(2,099)

1,716

Financial expenses - net

966

1,058

Consolidated income (loss) before income taxes

(3,065)

658

Revenues by Activity and Geographical Area

(Unaudited)

Three months ended

December 31,

Percentage

Change

2022

2021

2021-2022

(U.S.$ in millions)

North America segment

Generics products

818

905

(10%)

AJOVY

41%

AUSTEDO

344

282

22%

BENDEKA/TREANDA

(20%)

COPAXONE

101

129

(22%)

Anda

450

355

27%

Other

138

186

(26%)

Total

2,002

2,003

§ Represents an amount less than $0.5 million or 0.5%, as applicable

Three months ended

December 31,

Percentage

Change

2022

2021

2021-2022

(U.S.$ in millions)

Europe segment

Generics products

914

932

(2%)

AJOVY

19%

COPAXONE

(35%)

Respiratory products

(19%)

Other

119

(63%)

Total

1,129

1,268

(11%)

Three months ended

December 31,

Percentage

Change

2022

2021

2021-2022

(U.S.$ in millions)

International Markets segment

Generics products

411

438

(6%)

AJOVY

188%

COPAXONE

(19%)

Other

(34%)

Total

482

527

(9%)

Revenues by Activity and Geographical Area

(Unaudited)

Year ended

December 31,

Percentage

Change

2022

2021

2021-2022

(U.S.$ in millions)

North America segment

Generics products

3,549

3,769

(6%)

AJOVY

218

176

24%

AUSTEDO

963

802

20%

BENDEKA/TREANDA

316

385

(18%)

COPAXONE

387

577

(33%)

Anda

1,471

1,323

11%

Other

549

777

(29%)

Total

7,452

7,809

(5%)

Year ended

December 31,

Percentage

Change

2022

2021

2021-2022

(U.S.$ in millions)

Europe segment

Generics products

3,466

3,569

(3%)

AJOVY

124

43%

COPAXONE

268

391

(31%)

Respiratory products

273

356

(23%)

Other

393

483

(19%)

Total

4,525

4,886

(7%)

Year ended

December 31,

Percentage

Change

2022

2021

2021-2022

(U.S.$ in millions)

International Markets segment

Generics products

1,586

1,649

(4%)

AJOVY

(30%)

COPAXONE

(3%)

Other

246

295

(17%)

Total

1,903

2,032

(6%)

Free cash flow reconciliation

(Unaudited)

Three months ended December 31,

2022

2021

(U.S. $ in millions)

Net cash provided by operating activities

973

456

Beneficial interest collected in exchange for securitized accounts receivables

286

370

Purchase of property, plant and equipment

(142)

(153)

Proceeds from sale of business and long lived assets.

Free cash flow

1,140

716

Free cash flow reconciliation

(Unaudited)

Year ended December 31,

2022

2021

(U.S. $ in millions)

Net cash provided by operating activities

1,590

798

Beneficial interest collected in exchange for securitized accounts receivables

1,140

1,648

Purchases of property, plant and equipment

(548)

(562)

Proceeds from sale of business and long lived assets

311

Acquisition of businesses, net of cash acquired

(7)

Free cash flow

2,243

2,196

View source version on businesswire.com: https://www.businesswire.com/news/home/20230208005167/en/

IR Contacts

Ran Meir (267) 468-4475

Yael Ashman +972 (3) 914 8262

PR Contacts

Kelley Dougherty (973) 832-2810

Eden Klein +972 (3) 906 2645

Source: Teva Pharmaceutical Industries Limited

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Organizations

Teva Italia SRL

Teva Pharmaceutical Industries Ltd.Actavis Generics

[+5]

Indications

PainMigraine DisordersTardive Dyskinesia

[+2]

Targets

Drugs

Bendamustine HydrochlorideDeutetrabenazineGlatiramer Acetate

[+2]

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