Disease Domain | Count |
---|---|
Neoplasms | 2 |
Top 5 Drug Type | Count |
---|---|
Therapeutic vaccine | 2 |
Recombinant vector vaccine | 2 |
Top 5 Target | Count |
---|---|
CEACAM5 x MUC1 | 1 |
CD58 x CD80 x ICAM-1 x KLK3 | 1 |
Mechanism CD58 modulators [+4] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhasePhase 3 |
First Approval Ctry. / Loc.- |
First Approval Date- |
Target |
Mechanism CEACAM5 antagonists [+2] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhasePhase 2 |
First Approval Ctry. / Loc.- |
First Approval Date- |
Target- |
Mechanism Immunostimulants |
Active Org.- |
Originator Org. |
Active Indication- |
Inactive Indication |
Drug Highest PhaseDiscontinued |
First Approval Ctry. / Loc.- |
First Approval Date- |
Drug(Targets) | Indications | Global Highest Phase |
---|---|---|
Rilimogene galvacirepvec(National Cancer Institute) ( CD58 x CD80 x ICAM-1 x KLK3 ) | Metastatic castration-resistant prostate cancer More | Phase 3 |
Cancer vaccine(Therion Biologics Corp.) ( CEACAM5 x MUC1 ) | Prostatic Cancer More | Phase 2 |
MVA-BN-PRO(Bavarian Nordic) | Prostatic Cancer More | Discontinued |