Lmito Therapeutics is a clinical-stage pharmaceutical company developing novel therapies for autoinflammatory/autoimmune disorders and fibrotic diseases through metabolic reprogramming of mitochondrial and cellular metabolisms.

Disease Domain	Count

Immune System Diseases	4
Nervous System Diseases	2

Top 5 Drug Type	Count

Chemical drugs	4
Small molecule drug	3

Top 5 Target	Count

SARM1(sterile alpha and TIR motif containing 1)	1
PKM2(Pyruvate kinase isozymes M1/M2)	1

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Pipeline

Pipeline Snapshot as of 16 Dec 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Discovery

Preclinical

Phase 1 Clinical

Current Projects

Drug(Targets)	Indications	Global Highest Phase

LMT-503	Crohn Disease More	Phase 1
Immunometabolism modulator 2 (Lmito Therapeutics)	Rheumatoid Arthritis More	Preclinical
Fibrometabolism modulator 1(Lmito Therapeutics)	Idiopathic Pulmonary Fibrosis More	Preclinical
SARM1 program(Lmito Therapeutics) ( SARM1 )	Nervous System Diseases More	Preclinical
Charcot Marie tooth disease type 1A (Lmito Therapeutics)	Charcot-Marie-Tooth Disease, Type Ia More	Preclinical

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