[Translation] A multicenter, open-label, two-part Phase I/II trial evaluating the efficacy, safety, and pharmacokinetics of the combination of BNT323 and BNT327 in subjects with advanced breast cancer
Part I: 通过评估安全性确定BNT323和BNT327联合治疗的推荐II期剂量(RP2D)。
Part II: 评估BNT323单药治疗、BNT327单药治疗以及BNT323和BNT327联合治疗的安全性。
[Translation] Part I: Determine the recommended Phase II dose (RP2D) of BNT323 and BNT327 combination therapy by evaluating safety.
Part II: Evaluate the safety of BNT323 monotherapy, BNT327 monotherapy, and BNT323 and BNT327 combination therapy.