Hunan Province Sailong Pharmaceutical Co. Ltd.

To evaluate the efficacy and safety of dexlansoprazole for injection in the treatment of peptic ulcer bleeding, using lansoprazole for injection as a control.

The pharmacokinetic characteristics of the test preparation apixaban tablets (specification: 2.5 mg, produced by Hunan Sailon Pharmaceutical Co., Ltd.) and the reference preparation apixaban tablets (Aleto®, specification: 2.5 mg; produced by Bristol-Myers Squibb Manufacturing Company) were studied in healthy subjects after a single oral dose in the fasting and fed states, and the bioequivalence of the two preparations after oral administration in the fasting and fed states was evaluated.

The pharmacokinetic characteristics of the test preparation pregabalin capsules (specification: 150 mg, produced by Hunan Sailon Pharmaceutical Co., Ltd.) and the reference preparation pregabalin capsules (Lyrica®, specification: 150 mg; produced by Pfizer Manufacturing Deutschland GmbH, Betriebsstatte Freiburg) were studied in healthy subjects after a single oral administration in the fasting and fed state, the bioequivalence of the two preparations in the fasting and fed state was evaluated, and their safety in healthy subjects was studied.