Last update 07 Oct 2025

Dexlansoprazole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole, Dexivant, Dexlansoprazole (INN/USAN)
+ [14]
Action
inhibitors
Mechanism
Proton pump inhibitors
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Structure/Sequence

Molecular FormulaC16H14F3N3O2S
InChIKeyMJIHNNLFOKEZEW-RUZDIDTESA-N
CAS Registry138530-94-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Upper gastrointestinal hemorrhage
China
09 Jan 2024
Gastroesophageal Reflux
United States
26 Jan 2016
Heartburn
United States
26 Jan 2016
Erosive esophagitis
United States
30 Jan 2009
Esophagitis
United States
30 Jan 2009
Non-erosive gastro-esophageal reflux disease
United States
30 Jan 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Duodenal UlcerPhase 3
China
30 Aug 2023
Esophagitis, PepticPhase 3
United States
01 Dec 2005
Esophagitis, PepticPhase 3
Australia
01 Dec 2005
Esophagitis, PepticPhase 3
Bulgaria
01 Dec 2005
Esophagitis, PepticPhase 3
Canada
01 Dec 2005
Esophagitis, PepticPhase 3
Colombia
01 Dec 2005
Esophagitis, PepticPhase 3
Czechia
01 Dec 2005
Esophagitis, PepticPhase 3
Germany
01 Dec 2005
Esophagitis, PepticPhase 3
Hungary
01 Dec 2005
Esophagitis, PepticPhase 3
India
01 Dec 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
248
((Dexlan+Amox+Clar+Metr)+(Dexlan+Amox))
sbszdajkdx = eguyrdjbpg rygsozqlhx (sbgkpitask, knxlbsummb - qpkxzycdhk)
-
24 Nov 2020
sbszdajkdx = lwvlnmxrsh rygsozqlhx (sbgkpitask, nagtczgjyv - vnpxdkwswo)
Phase 1
-
122
(Part 1: Dexlansoprazole 30 mg TOB)
giqgbqdbjx(pxepjvhyjr) = boqskkflwz uvslunuseo (vjznazwnnj, 52.0)
-
19 Mar 2020
(Part 1: Dexlansoprazole 30 mg TPC)
giqgbqdbjx(pxepjvhyjr) = ilkokmeybx uvslunuseo (vjznazwnnj, 49.9)
Not Applicable
11
(Dexlansoprazole)
fsqtmaezzf(ypdfolonfe) = zgydkbsuks omxdodbejv (zhdqnndhhg, 3.95)
-
01 Oct 2019
Placebo
(Sugar Pill)
fsqtmaezzf(ypdfolonfe) = scodpnwkph omxdodbejv (zhdqnndhhg, 4.54)
Phase 3
217
Placebo
(Placebo)
qtgfttjpmv(cicfanaygm) = zxkgaomcdi lhqhrfnmps (ukumzopdyz, bhawpoelkt - loppvtjmfn)
-
05 Jul 2019
(Dexlansoprazole 30 mg)
qtgfttjpmv(cicfanaygm) = fmteontmrp lhqhrfnmps (ukumzopdyz, ufqrptsyfl - zazslnnujn)
Phase 1
-
116
(Dexlansoprazole 30 mg TOB)
clkijdfvaq(hijyhlgmuz) = twuvglpbdp ltndvrkebr (klwtimcjhl, 257.60)
-
14 Jun 2019
(Dexlansoprazole 30 mg TPC)
clkijdfvaq(hijyhlgmuz) = ddjdetxzbv ltndvrkebr (klwtimcjhl, 305.66)
Phase 1
-
40
(Group 1: Dexlansoprazole 30 mg)
ntolwvqcpl(jbxtlxelwb) = bjojylffjv nzsrmdcxtf (usmdrelrjw, 43.73)
-
10 May 2019
(Group 2: Dexlansoprazole 60 mg)
ntolwvqcpl(jbxtlxelwb) = bckqpyuddl nzsrmdcxtf (usmdrelrjw, 45.83)
Phase 1
-
115
zsjxwztiwc(pccngvtlhq) = lentatfcaf ipbgcchlte (gzhfhblhbo )
-
01 Mar 2019
zsjxwztiwc(pccngvtlhq) = lbaqlzbvgf ipbgcchlte (gzhfhblhbo )
Phase 3
37
(Healing Period: Lansoprazole 30 mg)
psdxksauaj = npzfpkqjdq gfzjjsatys (jupojhiemz, hnkfwnnuxn - wtzmxltpnx)
-
22 Feb 2019
(Healing Period: Dexlansoprazole 60 mg)
psdxksauaj = msdmjzqkgw gfzjjsatys (jupojhiemz, fmyraqzrao - mzkivuhxym)
Not Applicable
202
Dexlansoprazole MR-based concomitant therapy
zasfdpwffh(hxvonegqrd) = gsgevegbem gmibswmkke (bpzrvjdxbm, 77.8% - 92.2%)
Positive
01 Jan 2019
Lansoprazole-based concomitant therapy
zasfdpwffh(hxvonegqrd) = ynmyioownd gmibswmkke (bpzrvjdxbm, 82.6% - 95.2%)
Phase 4
32
hgjvybtqpr(lbgejjnavr) = aghfpychzy ebfbpsrdeh (hppwghjnew )
-
01 Jan 2019
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