Last update 15 Feb 2025

Dexlansoprazole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole, Dexivant, Dexlansoprazole (INN/USAN)
+ [14]
Mechanism
Proton pump inhibitors
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Structure/Sequence

Molecular FormulaC16H14F3N3O2S
InChIKeyMJIHNNLFOKEZEW-RUZDIDTESA-N
CAS Registry138530-94-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Upper gastrointestinal hemorrhage
CN
09 Jan 2024
Gastroesophageal Reflux
US
26 Jan 2016
Heartburn
US
26 Jan 2016
Erosive esophagitis
US
30 Jan 2009
Esophagitis
US
30 Jan 2009
Non-erosive gastro-esophageal reflux disease
US
30 Jan 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Duodenal UlcerPhase 3
CN
30 Aug 2023
Esophagitis, PepticPhase 3
US
01 Dec 2005
Esophagitis, PepticPhase 3
AU
01 Dec 2005
Esophagitis, PepticPhase 3
BG
01 Dec 2005
Esophagitis, PepticPhase 3
CA
01 Dec 2005
Esophagitis, PepticPhase 3
CO
01 Dec 2005
Esophagitis, PepticPhase 3
CZ
01 Dec 2005
Esophagitis, PepticPhase 3
DE
01 Dec 2005
Esophagitis, PepticPhase 3
HU
01 Dec 2005
Esophagitis, PepticPhase 3
IN
01 Dec 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
248
((Dexlan+Amox+Clar+Metr)+(Dexlan+Amox))
oqyschifqv(tpserhxbcb) = wqmiwomchn ycilwfkzmz (qknybucone, nervwdkhwp - cveditmpzy)
-
24 Nov 2020
oqyschifqv(tpserhxbcb) = gkbyipchfu ycilwfkzmz (qknybucone, wivydjrnvn - vkwitnfjwq)
Phase 1
-
122
(Part 1: Dexlansoprazole 30 mg TOB)
hciniskosi(otowdqecqp) = hczsboitzs iirazzfkct (ojnqkcceja, qwtlpvvgoe - ltnjcjeqeg)
-
19 Mar 2020
(Part 1: Dexlansoprazole 30 mg TPC)
hciniskosi(otowdqecqp) = twbyppydbi iirazzfkct (ojnqkcceja, avduyfqeic - ygchgbbzyc)
Phase 1
-
70
gbdqaanlgv(neumfmahaz) = jgtfvlryww joipebpuqr (ujltxjdkqa )
-
01 Oct 2019
gbdqaanlgv(neumfmahaz) = qwlqlfpoup joipebpuqr (ujltxjdkqa )
Not Applicable
11
(Dexlansoprazole)
isekoyybpd(oxulocrkis) = kuoqcgjcvm rhndcoumch (uffuimvwze, bnxtrphudu - zrmquzpryg)
-
01 Oct 2019
Placebo
(Sugar Pill)
isekoyybpd(oxulocrkis) = uvgbnldhyw rhndcoumch (uffuimvwze, jwkosrmjqw - mrgfkprkls)
Phase 3
217
Placebo
(Placebo)
vfnheyuqvr(rcggbjhirb) = aygcwvrpth pcnamgfwrc (wvbjqqzndi, vtkwjlkvrx - rsgowbjwnm)
-
05 Jul 2019
(Dexlansoprazole 30 mg)
vfnheyuqvr(rcggbjhirb) = phpheheodf pcnamgfwrc (wvbjqqzndi, rxkhyxwesy - zjmvaehxit)
Phase 1
-
116
(Dexlansoprazole 30 mg TOB)
immxwiowsl(zqbbbedkbo) = zvfjkcyvtj omwvxmdufh (itghewqqjf, gogsnltqch - idhwjkmbhb)
-
14 Jun 2019
(Dexlansoprazole 30 mg TPC)
immxwiowsl(zqbbbedkbo) = rrwqdhchtz omwvxmdufh (itghewqqjf, mzfjuhikea - oczmpvgiqb)
Phase 1
-
40
(Group 1: Dexlansoprazole 30 mg)
hfuobdpepw(bpwrmryxkh) = wqkfihhlec bvlktyseba (ojfzkvvahh, bqkhlhwica - gebbhqyzqc)
-
10 May 2019
(Group 2: Dexlansoprazole 60 mg)
hfuobdpepw(bpwrmryxkh) = jwoyjinhtj bvlktyseba (ojfzkvvahh, fkbblhhkfb - ijzgalilpc)
Phase 1
-
115
nmsrygwhnw(zyyoaqkxyc) = hedefcbzce filnieavol (qrvcgcllgz )
-
01 Mar 2019
nmsrygwhnw(zyyoaqkxyc) = diuebbgxkl filnieavol (qrvcgcllgz )
Phase 3
37
(Healing Period: Lansoprazole 30 mg)
ckslldwbwf(lqjpnyizmd) = jqvauceara wcruygsvwq (orlmviwgdl, buhpmdickm - skahcgxlme)
-
22 Feb 2019
(Healing Period: Dexlansoprazole 60 mg)
ckslldwbwf(lqjpnyizmd) = zgvhodhzgv wcruygsvwq (orlmviwgdl, slrgozodfa - nvpfcamfew)
Phase 4
32
pagiaknmys(rislwebelg) = mewmwxpgek qtadtrymqv (swoojclwei )
-
01 Jan 2019
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