R&D Pipeline

An Overview of Jiangsu Hengrui's 257 Drug Pipelines ——Top 50 Pharmaceutical Companies R&D Progress

26 July 2023
3 min read

Jiangsu Hengrui Pharmaceutical Group Co. Ltd. is a pharmaceutical organization based in Jiangsu Sheng, China. It was founded in 1996 and has since become a prominent player in the biomedicine field. The company has a diverse portfolio of drugs targeting various therapeutic areas, with a strong focus on oncology.

Jiangsu Hengrui Pharmaceutical Group Co. Ltd. has developed a significant number of drugs in the field of neoplasms, with a count of 98. This indicates the company's commitment to addressing the growing burden of cancer and developing innovative treatments for patients. The second-highest therapeutic area is endocrinology and metabolic disease, with 38 drugs. This suggests that the company recognizes the importance of addressing conditions related to hormonal imbalances and metabolic disorders.

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The company has also shown interest in developing drugs for skin and musculoskeletal diseases, urogenital diseases, respiratory diseases, immune system diseases, and nervous system diseases, with drug counts ranging from 30 to 36. This demonstrates the company's dedication to addressing a wide range of medical conditions and improving patient outcomes in these areas.

In terms of drug targets, Jiangsu Hengrui Pharmaceutical Group Co. Ltd. has focused on several key targets. The most frequently developed target is SCNA, with four drugs targeting this specific protein. Other notable targets include URAT1, HER3, ER, GLP-1R, DPP-4, CEA, GABAA receptor, HER2, CTLA4, COX-2, TOP1, SGLT2, SOST, Tubulin, CLDN18.2, IL-2, and NMDA receptor, each with two drugs targeting them. These targets represent a diverse range of proteins and receptors involved in various disease pathways, indicating the company's commitment to developing drugs that target specific mechanisms of action.

Looking at the pipeline of Jiangsu Hengrui Pharmaceutical Group Co. Ltd., it is evident that the company has a robust and active pipeline. The majority of drugs are in the discovery phase, with 43 drugs currently being explored for potential therapeutic applications. This highlights the company's commitment to research and development and its continuous efforts to identify new drug candidates.

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The preclinical phase follows the discovery phase, with nine drugs undergoing further testing and evaluation before advancing to the next stages. The IND (Investigational New Drug) phase comes next, with ten drugs currently in this stage. This phase involves submitting an application to regulatory authorities for permission to conduct clinical trials.

Phase 2 follows, with 30 drugs currently in this stage. Phase 2 trials involve a larger number of patients and aim to evaluate the drug's effectiveness and side effects. Phase 3 trials, on the other hand, have 12 drugs and involve a larger patient population to further assess the drug's safety and efficacy.

In summary, Jiangsu Hengrui Pharmaceutical Group Co. Ltd. is a leading pharmaceutical organization in China, with a strong focus on the development of drugs for various therapeutic areas. The company has a significant presence in the field of oncology, with a high number of drugs targeting neoplasms. Additionally, it has shown interest in addressing endocrinology and metabolic diseases, skin and musculoskeletal diseases, urogenital diseases, respiratory diseases, immune system diseases, and nervous system diseases.

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