Sucralfate is a medication that was first approved in Japan in February 1968 by Allergan. The drug is used for the short-term treatment of active duodenal ulcer and works by creating a protective coating over the ulcer site, which helps to promote healing and prevent further damage. Sucralfate's active ingredient is an α-D-glucopyranoside, β-D-fructofuranosyl-, octakis-(hydrogen sulfate), aluminum complex. This complex interacts with positively charged proteins in the ulcer site to form a barrier that protects the damaged tissue. Sucralfate is typically taken orally, and should be taken on an empty stomach for maximum effectiveness. While generally well-tolerated, the medication may cause gastrointestinal side effects such as nausea, constipation, and diarrhea. Click on the image below to begin the exploration journey of Sucralfate through the Synapse database!
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