Pharmaceutical Insights
Navigate pharmaceutical trends with our insights on targets, institutional pipelines, clinical advances, and new drugs.
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Recent blog posts
Nanobiotix Concludes Phase 1 Dose Escalation, Determines Phase 2 Dose for NBTXR3 in Re-Irradiation-Eligible Recurrent Lung Cancer
Pharma Pioneer
2 min read
Nanobiotix Concludes Phase 1 Dose Escalation, Determines Phase 2 Dose for NBTXR3 in Re-Irradiation-Eligible Recurrent Lung Cancer
17 May 2024
NANOBIOTIX has completed the dose escalation phase of a Phase 1 study evaluating NBTXR3, a potential first-in-class radioenhancer.
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Corbus Commences U.S. Phase 1 Trial with First Patient Dosed for Next-Gen Nectin-4 ADC CRB-701
Pharma Pioneer
2 min read
Corbus Commences U.S. Phase 1 Trial with First Patient Dosed for Next-Gen Nectin-4 ADC CRB-701
17 May 2024
Corbus Pharmaceuticals, a precision oncology firm, has initiated a Phase 1 clinical trial in the U.S. for CRB-701 (SYS6002)
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Verve Therapeutics Pauses Gene-Editing Clinical Trial Following Patient's Adverse Reaction
Pharma Pioneer
2 min read
Verve Therapeutics Pauses Gene-Editing Clinical Trial Following Patient's Adverse Reaction
17 May 2024
A clinical trial for a gene-editing treatment by Verve Therapeutics, known as VERVE-101, has been halted after a participant experienced severe side effects.
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Ractigen Commences Phase I Clinical Trial with First Patient Treated for NMIBC Using RAG-01
Pharma Pioneer
2 min read
Ractigen Commences Phase I Clinical Trial with First Patient Treated for NMIBC Using RAG-01
17 May 2024
In a significant medical advancement, Ractigen Therapeutics has initiated its first-ever human clinical trial for RAG-01, a novel small activating RNA (saRNA) treatment for NMIBC.
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Verismo Submits FDA Application for IND Approval of SynKIR™-310 for Treating Recurrent or Refractory B-cell NHL
Pharma Pioneer
2 min read
Verismo Submits FDA Application for IND Approval of SynKIR™-310 for Treating Recurrent or Refractory B-cell NHL
17 May 2024
Verismo Therapeutics, a company specializing in CAR T-cell therapies, is progressing with its second clinical trial using the SynKIR™ platform.
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Preliminary Phase 1/2 Clinical Trial Results for mRNA-3927, a Potential mRNA Treatment for Propionic Acidemia, Featured in Nature Journal
Pharma Pioneer
2 min read
Preliminary Phase 1/2 Clinical Trial Results for mRNA-3927, a Potential mRNA Treatment for Propionic Acidemia, Featured in Nature Journal
17 May 2024
Moderna, a biotechnology company, has reported preliminary results from a phase 1/2 clinical trial for mRNA-3927.
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Achilles Therapeutics Reports Interim Phase I/IIa Results for Clonal Neoantigen T Cells in NSCLC and Melanoma with Enhanced Conditioning
Pharma Pioneer
3 min read
Achilles Therapeutics Reports Interim Phase I/IIa Results for Clonal Neoantigen T Cells in NSCLC and Melanoma with Enhanced Conditioning
17 May 2024
Achilles Therapeutics plc has reported interim Phase I/IIa clinical trial data for clonal neoantigen reactive T cells (cNeT) from the CHIRON study for non-small cell lung cancer (NSCLC) and the THETIS study for malignant melanoma
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CureVac Reveals Positive Interim Phase 2 Results for Seasonal Flu Vaccine in Partnership with GSK
Pharma Pioneer
3 min read
CureVac Reveals Positive Interim Phase 2 Results for Seasonal Flu Vaccine in Partnership with GSK
17 May 2024
This innovative vaccine, developed by CureVac, is multivalent and contains antigens that match the four flu strains recommended by the World Health Organization (WHO).
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Eilean Therapeutics Granted Approval to Launch Phase I R/R AML Clinical Trial Utilizing Lomonitinib, a Targeted FLT3/IRAK4 Inhibitor
Pharma Pioneer
2 min read
Eilean Therapeutics Granted Approval to Launch Phase I R/R AML Clinical Trial Utilizing Lomonitinib, a Targeted FLT3/IRAK4 Inhibitor
17 May 2024
Eilean Therapeutics LLC has received approval from the Human Research Ethics Committee in Australia to commence a Phase I clinical trial for lomonitinib (ZE46-0134).
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International Wound Journal Publishes Microbion's Phase 1b Study on Pravibismane for Treating Diabetic Foot Ulcer Infections
Pharma Pioneer
3 min read
International Wound Journal Publishes Microbion's Phase 1b Study on Pravibismane for Treating Diabetic Foot Ulcer Infections
17 May 2024
A recent Phase 1b clinical trial of topical pravibismane for managing moderate to severe diabetic foot ulcers has shown promising results.
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Positive Clinical Results from TPST-1120 Phase 1 Trial for Advanced Solid Tumors Published in Cancer Research Journal
Pharma Pioneer
3 min read
Positive Clinical Results from TPST-1120 Phase 1 Trial for Advanced Solid Tumors Published in Cancer Research Journal
17 May 2024
TPST-1120, a novel oral PPAR⍺ inhibitor, has shown promising results in treating cancers that are resistant to PD-1 inhibitors and those with weakened immune systems.
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ADC Therapeutics Provides LOTIS-7 Trial Updates on ZYNLONTA Combos for Relapsed/Refractory B-cell Lymphoma
Pharma Pioneer
2 min read
ADC Therapeutics Provides LOTIS-7 Trial Updates on ZYNLONTA Combos for Relapsed/Refractory B-cell Lymphoma
17 May 2024
LOTIS-7 Phase 1b Trial Completes Dose Escalation: ZYNLONTA® and Bispecific Antibodies for Non-Hodgkin Lymphoma Patients, No Severe Side Effects Observed.
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