Innate Pharma Showcases Pre-IND Candidate IPH45's Preclinical Results at AACR 2024 - A New Antibody-Drug Conjugate Targeting Nectin-4.

Synthekine Unveils Encouraging Early Outcomes from Early-stage Clinical Study of Altered IL-2 Agent, STK-012, Aimed at Advanced Solid Cancer Therapy.

Obsidian Therapeutics Reveals Encouraging Safety and Effectiveness Results After 25 Weeks of Monitoring in Initial Human Trials for OBX-115.

CytomX Therapeutics has revealed initial treatment using CX-2051, a selective EpCAM-targeted antibody-drug conjugate, in an early-stage trial involving individuals with progressive solid malignancies.

April 12th latest updates in the global new drug development field, including progress in new drug research and development, transaction information, and partnership developments.

CHS-1000, an Innovative ILT4 Antagonist Antibody, Showcased Through Early-Stage Research at AACR's 2024 Gathering.

Vivet Therapeutics Administers Initial Dose to First Participant in Second Group of Phase 1/2 GATEWAY Study for Wilson Disease Therapy.

Up to now, at the AACR meeting, updates on the clinical progress of several ADC drugs have been presented, involving targets such as HER2, BCMA, CD123, FRα, CCR7, Axl, etc.

Promising Early Results for SCB-1019 Vaccine in Young Adults: Clover Biopharmaceuticals Phase I Insights.

The high failure rate of clinical trials, often cited to be around 90%, can be attributed to several factors.

Ichnos Glenmark Innovation Unveils Early Findings for Cancer Candidate ISB 2001 at AACR 2024.

The failure of clinical trials can stem from multiple factors. One study suggests that 90% of drug development clinical failures may be attributed to four reasons: lack of clinical efficacy (40%-50%), uncontrollable toxicity (30%), poor pharmacokinetic properties (10%-15%), and absence of commercial demand or poor strategic planning (10%).