To optimize drug dosage adjustments for individual patient profiles in the context of combination therapy, several factors should be considered.

Tiziana Life Sciences Ltd. has announced the start of a Phase 2a trial, assessing the efficacy and safety of two doses of intranasal foralumab compared to placebo in patients with non-active secondary-progressive multiple sclerosis.

TLR7 agonists are compounds that activate the Toll-like receptor 7, stimulating the immune system against viral infections.

Mabwell announced the NMPA's approval of its IND application for 8MW0511, an innovative injectable recombinant fusion protein drug.

In the U.S. FDA context, "Requirement/Commitment Status" generally refers to a manufacturer's or sponsor's obligations for regulatory approval, post-approval studies, or marketing authorization conditions for drugs, devices, or regulated products.

Telix Pharmaceuticals has submitted a BLA to the U.S. FDA for TLX250-CDx (Zircaix™), a PET scan diagnostic agent for clear cell renal cell carcinoma.

Syk inhibitors are drugs that target and inhibit the spleen tyrosine kinase enzyme, crucial in immune cell signaling.

Santhera Pharmaceuticals has declared that its drug, AGAMREE® (vamorolone), has received authorization within the European Union to be prescribed for those diagnosed with Duchenne muscular dystrophy.

InnoCare Pharma has announced that their phase II trial of the novel TYK2 inhibitor ICP-332 met its primary endpoint in treating adults with moderate to severe atopic dermatitis.

NOS inhibitors are drugs that inhibit nitric oxide synthase, an enzyme crucial in various physiological processes.

Drug combinations can improve drug resistance by targeting multiple pathways or mechanisms simultaneously, making it more difficult for the cancer cells to develop resistance.

Caliway Finalizes Funding Round Exceeding Targets, Locks in Excess of $100M for Critical Phase 3 Trial of CBL-514 for Subcutaneous Fat Reduction.