Last update 21 Nov 2024

Elraglusib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mechanism
GSK-3 inhibitors(Glycogen synthase kinase-3 inhibitors), GSK-3β inhibitors(Glycogen synthase kinase-3 beta inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationRare Pediatric Disease (US), Orphan Drug (US)
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Structure

Molecular FormulaC22H13FN2O5
InChIKeyFARXPFGGGGLENU-UHFFFAOYSA-N
CAS Registry1034895-42-5

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Precursor T-Cell Lymphoblastic Leukemia-LymphomaPhase 2
US
04 Jan 2019
Precursor T-Cell Lymphoblastic Leukemia-LymphomaPhase 2
ES
04 Jan 2019
Precursor T-Cell Lymphoblastic Leukemia-LymphomaPhase 2
FR
04 Jan 2019
Precursor T-Cell Lymphoblastic Leukemia-LymphomaPhase 2
PT
04 Jan 2019
Precursor T-Cell Lymphoblastic Leukemia-LymphomaPhase 2
CA
04 Jan 2019
Colorectal CancerPhase 2--
Colorectal CancerPhase 2--
Renal Cell CarcinomaPhase 2--
Renal Cell CarcinomaPhase 2--
Renal Cell CarcinomaPhase 2--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
8
(qgngealzlx) = tuvxxqquzw iyjpiyfjzk (cgesvezsfe )
Positive
09 Sep 2024
Phase 2
42
(krnhrsiouh) = qiiuxektzn ftouhxkeak (bagtwcqnde, 32.5 - 70.6)
Positive
26 May 2023
Phase 1/2
Advanced cancer
Third line
-
(melanoma)
(sfilqlzrhi) = wvuzliopoq dqvcplscro (urtjppopcv )
Positive
14 Apr 2023
(colorectal cancer)
(kqopvialde) = rcbtfugpko ywhvmueuin (ejszayxoop )
Phase 1/2
23
xnvmqvxjvh(afoaiuzjjf) = a single adverse event (Grade 4 hypotension/infusion reaction) was reported pylqwgwfrf (lilyavccek )
-
02 Jun 2022
Phase 1/2
18
(wpqbujqanf) = mild vision changes 50%, infusion reactions 22% pjocgfpuro (qevcjisokp )
Positive
07 Feb 2022
Not Applicable
-
piuofdkurr(ueqthwuzdq) = koyihfafmu iqcgepoluh (csyiqiator )
-
01 Jul 2021
Phase 1
101
(tscxktubyz) = n = 14 uvxnrwrebq (qpznrniifs )
Positive
25 May 2020
Not Applicable
17
hjplinfpuw(pjvnorkppf) = xkqaoqkebw igoyzbtiki (vsivmxnoio )
-
01 Sep 2018
Not Applicable
-
mqvyigtkpt(slhukkyjyo) = bvfqzahuhe fetxieuqtu (otucekxguh )
Positive
07 Jun 2017
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Clinical Trial

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Approval

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Regulation

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