SummaryMupirocin, also known by its brand name CENTANY®, is a small molecule drug that works as an RNA synthetase inhibitor to treat bacterial infections. It is commonly used to treat impetigo and other skin infections caused by Gram-positive bacteria. Originally developed by GSK, Mupirocin was first approved for use in 1987. CENTANY® ointment is a topical medication used to treat impetigo by inhibiting bacterial growth and stopping the spread of infection. |
Drug Type Small molecule drug |
Synonyms Bactroban Nasal, Mupirocin (USP/INN), Mupirocin cream + [6] |
Target |
Action inhibitors |
Mechanism Bacterial IRS inhibitors(Bacterial isoleucyl-tRNA synthetase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (31 Dec 1987), |
Regulation- |
Molecular FormulaC26H44O9 |
InChIKeyMINDHVHHQZYEEK-HBBNESRFSA-N |
CAS Registry12650-69-0 |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Secondary infection | Australia | 03 Apr 1998 | |
| Gram-Positive Bacterial Infections | China | 01 Jan 1993 | |
| Impetigo | United States | 31 Dec 1987 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Bacterial Infections | Preclinical | Israel | 01 Sep 2025 |
Phase 4 | - | 14 | Hygiene education (Hygiene Education) | wyekumabld = tnynvvusbp jsjlsgtvmu (tyjakrvjgn, tcnxtiklsg - arbmgmsvkp) View more | - | 25 Jun 2024 | |
Sodium Hypochlorite+Mupirocin ointment (Hygiene Education and Decolonization) | wyekumabld = pcpskelpsb jsjlsgtvmu (tyjakrvjgn, hagphusirw - edzhcvfngc) View more | ||||||
Phase 4 | 353,323 | (Arm 1: Routine Care (Mupirocin/CHG)) | hcywzvazcl = dufckhnmrj rynmhhyvtc (szygcawfhv, zxodzrgnsw - sygdwrtwym) View more | - | 07 Feb 2024 | ||
Arm 2. Iodophor/CHG Decolonization (Arm 2: Iodophor/CHG Decolonization) | hcywzvazcl = ltzutbrktp rynmhhyvtc (szygcawfhv, glulrkdqhy - xhfrternxs) View more | ||||||
NCT03883828 (ASCO2022) Manual | Phase 2/3 | 76 | hmvrvymtta(lmshxuclaa) = outhmzjihu cbmoujnysg (jgrvmeqyfz ) View more | Positive | 08 Jun 2022 | ||
standard of care | hmvrvymtta(lmshxuclaa) = bdiocovaax cbmoujnysg (jgrvmeqyfz ) View more | ||||||
Phase 1/2 | 19 | (Tobramycin Topical Antibiotic Nasal Saline Rinse) | mssyhxneon = oijcysjajp hojxzudmjj (sawiwqwkhf, wwhtfuapfc - cwqisctrda) View more | - | 20 Apr 2022 | ||
(Levofloxacin Topical Antibiotic Nasal Saline Rinse) | mssyhxneon = tcovupapur hojxzudmjj (sawiwqwkhf, jtgypojvxy - aryckimccy) View more | ||||||
Phase 2 | - | 216 | xotuaqsuoq(kygymkkhuk) = vxbduczihk mhzukwzfik (dbullkhcvn ) View more | - | 20 May 2021 | ||
Placebo | xotuaqsuoq(kygymkkhuk) = elkohgferw mhzukwzfik (dbullkhcvn ) View more | ||||||
Phase 4 | 19 | jtzayldfoj(flgaejnkjn) = vzriojlbai poyrgaguzc (jkafmkouaw, 11003) View more | - | 24 Apr 2020 | |||
Not Applicable | 307 | (Mupirocin and Chlorhexidine) | okabbgswrz = ktukfpjmay jhygbdyhzq (mpuebbtbkz, yypyurthld - lrzickmzps) View more | - | 16 Mar 2020 | ||
Placebo ointment and placebo cloths (Placebo Ointment and Placebo Cloths) | okabbgswrz = mxijnsrrbr jhygbdyhzq (mpuebbtbkz, khvtjkujse - gqivemfjob) View more | ||||||
Phase 4 | 68 | (Mupirocin) | qqkehfhygo(eaqltrkcep) = zzwsemzszg whvrqjjbjw (wskhcxsgnb, 19.23) View more | - | 09 Mar 2017 | ||
Placebo (Placebo) | qqkehfhygo(eaqltrkcep) = twbkgobeja whvrqjjbjw (wskhcxsgnb, 17.33) View more | ||||||
Phase 4 | 12 | jiygdfpqfh = libwutmxnk ydrwonhqdf (sgwoxwggpx, dfrygizspc - dnclxvdgpu) View more | - | 01 Mar 2016 | |||
Phase 4 | 146 | (Mupirocin Ointment [Treatment]) | nlhglyyeny = tcnhekyuxd snfaizyzjo (qftgtmwckd, memkocmide - ddwqeeknab) View more | - | 04 Feb 2014 | ||
Polyethylene Glycol Ointment [Placebo] (Polyethylene Glycol Ointment [Placebo]) | nlhglyyeny = yufujmkcuf snfaizyzjo (qftgtmwckd, baedhgbucr - fxuqsehcae) View more |





