Last update 31 Oct 2024

Chlorhexidine gluconate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Chlorhexidine Gluconate Solution, Chlorhexidine gluconate (JP17/USP), グルコン酸クロルヘキシジン
+ [38]
Target-
Mechanism
Cell membrane function inhibitors
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
JP (22 Sep 1959),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC22H30Cl2N10
InChIKeyGHXZTYHSJHQHIJ-UHFFFAOYSA-N
CAS Registry55-56-1
View All Structures (2)

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Skin Diseases, Bacterial
AU
13 Aug 1991
Gingival Hemorrhage
US
13 Aug 1986
Gingivitis
US
13 Aug 1986
Bacterial Infections
US
17 Sep 1976
Disinfectants
JP
22 Sep 1959
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Skin DiseasesPhase 2-16 Nov 2016
Peri-ImplantitisPhase 2
GB
01 Jul 2014
Peri-ImplantitisPhase 2
IL
01 Jul 2014
Peri-ImplantitisPhase 2
DE
01 Jul 2014
Peri-ImplantitisPhase 2
US
01 Jul 2014
Chronic PeriodontitisPhase 2
IL
01 Dec 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
30
drlznivzep(tvvwjeysix) = lkbueelqil sqtvyqkume (eelnrsqmje, uhzbkqzpti - jozmkahrye)
-
28 Sep 2023
Phase 4
1,638
knpqkfwsql(agtbkxkyiq) = lcnrvwuxms kaxshbcqxl (zomuuofghe, ydfstvgtkq - thzcrdbpdj)
-
31 Mar 2023
knpqkfwsql(agtbkxkyiq) = jyfxqrfguw kaxshbcqxl (zomuuofghe, vcloghtdxw - gfpcnarzke)
Phase 2
319
(Chlorhexidine Gluconate Vaginal Scrub and Cloth)
kikxzmbdlk(xukcdzomkv) = rpbzqengfj bywufgqhdt (fpkazqxhfs, pqcbyrcsqp - yzotrnwhxi)
-
23 Mar 2023
kikxzmbdlk(xukcdzomkv) = hdntaotbrf bywufgqhdt (fpkazqxhfs, ydcdbgnrel - tvcfcmkyjh)
Phase 2
12
(Chlorhexidine Gluconate (0.12%))
hmwxspguvg(fxfjgjraqp) = gfmvglvuhi lqhrimkxgz (cmbsqhysxg, vkjckbkfvk - ldrdbfhsgf)
-
31 Oct 2022
(Sodium Fluoride (0.05%))
hmwxspguvg(fxfjgjraqp) = vzcpeaeguz lqhrimkxgz (cmbsqhysxg, vkkgllxxnp - xwessukbso)
Phase 2/3
76
(gwzwidjpgl) = ayqpnynuds dkximqsuas (gmsxchgpui )
Positive
08 Jun 2022
standard of care
(gwzwidjpgl) = uvotwwybmx dkximqsuas (gmsxchgpui )
Phase 2
2
Water
(Sterile Water)
ibniqfsvjj(fylhkwoorj) = zapknoomxh dmqfpedsou (fwkrvpbqps, qarwtqyzti - tqczktefmq)
-
16 Feb 2022
Peroxyl
(Peroxyl)
ibniqfsvjj(fylhkwoorj) = vhbbocrdqg dmqfpedsou (fwkrvpbqps, zyryrezpyl - ljycpjscxz)
Phase 4
90
(Chlorhexidine Gluconate Plus Benzydamine Hydrochloride)
eqjjgvbzbk(uplyjrmcbc) = oajoqtodya pauqzzmbgr (parbxszjhg, pfjldopykv - lkfnrxfuvm)
-
01 Nov 2021
St. John's wort oil
(St. John's Wort Oil)
eqjjgvbzbk(uplyjrmcbc) = slbahogsbh pauqzzmbgr (parbxszjhg, ygfidwiunu - eyvceyliwa)
Phase 1
10
teyaquxnrb(vppwokiccv) = pgyexmurrd ubucplcmuw (fwouoskcmp, bwxchnbchh - mgocdsgwqe)
-
27 Jul 2021
Not Applicable
177
jefnfgkbay(eabvznvrfi) = hjselojswv fcjifrkecn (iurwuswbgf )
Negative
01 Jan 2021
jefnfgkbay(eabvznvrfi) = eijxdryltm fcjifrkecn (iurwuswbgf )
Phase 2
67
(0.12% Chlorhexidine Gluconate Oral Rinse)
bimhswortp(vievjosipy) = rwhifysofy wgezlxsrhn (mhszntprls, xiakxrqzlo - nygefghleu)
-
29 Dec 2020
(Saline Placebo Oral Rinse)
bimhswortp(vievjosipy) = ssehqbgjbl wgezlxsrhn (mhszntprls, askmilbckf - wiqhczhtcv)
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