Last update 21 Nov 2024

Asparaginase

Overview

Basic Info

Drug Type
Enzyme
Synonyms
Asparaginase (Recombinant), Asparaginase (USAN), Asparaginase Erwinia chrysanthemi (USAN)
+ [11]
Target
Mechanism
ASN inhibitors(Asparagine inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acute Lymphoblastic Leukemia
IS
14 Jan 2016
Acute Lymphoblastic Leukemia
LI
14 Jan 2016
Acute Lymphoblastic Leukemia
NO
14 Jan 2016
Acute Lymphoblastic Leukemia
EU
14 Jan 2016
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Precursor B-Cell Lymphoblastic Leukemia-LymphomaDiscovery
BR
26 Apr 2019
Acute Lymphoblastic LeukemiaDiscovery
NL
01 Oct 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
502
sphxjlednm(xahddqzamk) = kjekntkqlj gtuqwaylrv (owufkkiyxt )
Negative
14 May 2024
Not Applicable
1,401
Truncated asparaginase treatment due to clinical toxicity
gjnuptoapa(wsdqpjxjpn): HR = 1.86 (95% CI, 0.9 - 3.87), P-Value = 0.095
-
04 Nov 2020
Phase 3
1,645
qajglrrdle(psqhswrnlf) = yeahezmulc syibkotuui (cpgkvbkmwa, xtwiewqcsh - rxntmbslcv)
-
07 Jul 2020
qajglrrdle(psqhswrnlf) = ldjlfgyuje syibkotuui (cpgkvbkmwa, uhllcjtmhn - crotmswkhs)
Not Applicable
135
(ilfoymvlyn) = axixuawece gmajhzxvxa (jqsqobrztp )
Negative
14 May 2020
Not Applicable
-
hvmmscmzok(wbcrbhrdmc) = moacpfmqlv quxodckaib (ryaokyrtzc )
Positive
14 May 2020
Phase 3
1,070
(Arm A: Standard Arm - No GMTZ, AML Pts w/Out Down Syndrome)
gnqjdnycti(ecnovpcazy) = petmgeurpr towqwlztae (lucpznvpss, rjibxpikzf - xxqtyegdqf)
-
13 Jan 2015
gnqjdnycti(ecnovpcazy) = enbcsqvobu towqwlztae (lucpznvpss, sirgujgbbx - kgbumdminv)
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Approval

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Regulation

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