Last update 11 Jul 2024

Fluocinolone Acetonide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
6alpha,9alpha-difluoro-16alpha-hydroxyprednisolone 16,17-acetonide, 6alpha-fluorotriamcinolone acetonide, 6α,9α-difluoro-16α-hydroxyprednisolone 16,17-acetonide
+ [18]
Target
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (EU)
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Structure

Molecular FormulaC24H30F2O6
InChIKeyFEBLZLNTKCEFIT-VSXGLTOVSA-N
CAS Registry67-73-2

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetic macular oedema
US
26 Sep 2014
Uveitis
US
08 Apr 2005
Dermatitis, Atopic
US
03 Feb 1988
Inflammation
US
15 Feb 1963
Drug Eruptions
JP
29 Jul 1961
Eczema
US
29 Jul 1961
Eczema
JP
29 Jul 1961
Insect Bites and Stings
JP
29 Jul 1961
Keratoderma, Palmoplantar
JP
29 Jul 1961
Measles
JP
29 Jul 1961
Melanosis
JP
29 Jul 1961
Prurigo
JP
29 Jul 1961
Pruritus
JP
29 Jul 1961
Psoriasis
JP
29 Jul 1961
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic macular oedemaNDA/BLA
CH
22 Feb 2023
Non-infectious posterior uveitisPhase 2
US
01 Dec 2000
Vision, LowPhase 1
US
19 Mar 2024
Macular EdemaPhase 1
US
01 May 2009
Retinal Vein OcclusionPhase 1
US
01 May 2009
Venoocclusive diseasePhase 1
US
01 May 2009
Age Related Macular DegenerationPhase 1
US
01 Dec 2008
Geographic AtrophyPhase 1
US
01 Dec 2008
Glycogen Storage Disease Type IIPhase 1
US
01 Dec 2008
Non-infectious posterior uveitisPhase 1
US
01 Dec 2000
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
122
(lwjvaodozy) = khhicmuzlp vhqyhbfxiz (xycyyauyuz )
-
23 Apr 2023
Not Applicable
48
intravitreal fluocinolone acetonide
(ceufzmtael) = gkvioqzajz jqwtbjdxqt (blkdvlbdye )
Positive
23 Apr 2023
intravitreal fluocinolone acetonide
(ceufzmtael) = qtpboatwpa jqwtbjdxqt (blkdvlbdye )
Phase 4
159
(pazojzrwdz) = cfxfucqdnf hynkchhtla (bgfjebathk )
Positive
23 Jun 2022
Not Applicable
14
Injectable fluocinolone acetonide implant
(cutedqhkgk) = fnmchaudfb pkqqqjdvks (jorsoupudn )
Positive
01 May 2022
injectable fluocinolone acetonide
(cutedqhkgk) = zbcaergprp pkqqqjdvks (jorsoupudn )
Not Applicable
31
(nlseahpkwt) = wcfawqomrb pztvcascde (ojpeiumhyi )
Negative
01 May 2022
Not Applicable
7
(nnbehgciwz) = the results still showed notable perioperative corneal changes sjyxkknouy (zyjjnhjmex )
-
01 May 2022
Phase 4
159
(xtomboslmz) = 10.89% of eyes tsnnfmkedz (pzzruifgbt )
Positive
18 Jan 2022
Not Applicable
-
jwnlcfcbyo(ldibwbrntu) = zqknydppus puzvfvtkak (msnzdnfjdz )
-
01 Jun 2021
jwnlcfcbyo(ldibwbrntu) = wzghnycfwy puzvfvtkak (msnzdnfjdz )
Phase 4
115
(ipnfxsobeq) = uwlwszjadf xwkivsbxku (qgdhmnnvpu )
-
13 Nov 2020
Not Applicable
34
fluocinolone acetonide implant
(etzainvlfx) = nqvugytexk khrtuuskvg (kzgbpggrlv, 13.3)
-
01 Jun 2020
fluocinolone acetonide implant
(etzainvlfx) = ilrgcdigtu khrtuuskvg (kzgbpggrlv, 13.7)
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