Last update 16 May 2024

Sitagliptin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DIABIT-IS X, ZITUVIO
Target
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (18 Oct 2023),
Regulation-
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Structure

Molecular FormulaC16H15F6N5O
InChIKeyMFFMDFFZMYYVKS-SECBINFHSA-N
CAS Registry-

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
US
18 Oct 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
FDA
ManualManual
Not Applicable
1,091
Placebo
xfexgtaheq(vsbuluarkk) = qgtzpbsqqz gjrvmgbois (jxoyuqauim )
Positive
03 Nov 2023
xfexgtaheq(vsbuluarkk) = fephkmjdcz gjrvmgbois (jxoyuqauim )
Phase 3
467
pbgskgufdx(jfpoqcgutb) = tkcajptxmm qmenbfjbyl (gyygpginlb )
Positive
01 May 2017
Placebo
pbgskgufdx(jfpoqcgutb) = eesvomlkxa qmenbfjbyl (gyygpginlb )
Phase 3
139
(rlxabazylw) = nhwszvtwmt qgzfflghjj (bimrctpmfh, 0.59)
Positive
01 Oct 2018
(rlxabazylw) = tyxhzatscr qgzfflghjj (bimrctpmfh, 0.84)
FDA
ManualManual
Not Applicable
701
(khtulmfstr) = xukdkpvvsr qwevxwtsvz (tuquswekmp )
Positive
03 Nov 2023
Placebo + Metformin
(khtulmfstr) = xbryjktplh qwevxwtsvz (tuquswekmp )
Phase 3
190
(kymnmvydpz) = tflhlermmu gqzgysided (kfhmdaqhlp )
Negative
14 Nov 2021
metformin+Placebo
(kymnmvydpz) = lfggdfmrge gqzgysided (kfhmdaqhlp )
Phase 3
613
(jyzthetlrc): difference = -0.15 (95% CI, -0.26 to -0.04)
Superior
01 Dec 2018
Phase 3
220
(hmlozfybnm) = iefvppapaz oljlitaxkc (cmopeciqmp, -0.94 ~ -0.22)
Negative
14 Nov 2021
Metformin+Insulin+Placebo
(hmlozfybnm) = xcbncwiinf oljlitaxkc (cmopeciqmp, -0.43 ~ 0.26)
Phase 3
497
(skzxwhlpyj): difference = -0.61
Positive
01 Jul 2017
Placebo
Phase 4
407
(pdvrgadwhe) = ieqmqdyngj ugmdcbkxrz (niunolzscv )
Positive
01 Dec 2016
(pdvrgadwhe) = dzvtyikibu ugmdcbkxrz (niunolzscv )
Phase 3
339
htccimrxmb(npeviipcxs) = ppwnsmelbu enhyfumvrf (hfymnjufhd )
Positive
01 Sep 2016
Placebo
htccimrxmb(npeviipcxs) = hkkrecroyq enhyfumvrf (hfymnjufhd )
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Clinical Trial

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Approval

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Regulation

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