Last update 20 Jul 2024

Avexitide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Avexitide (USAN), Avexitide acetate, EXENDIN (9-39)
+ [7]
Target
Mechanism
GLP-1R antagonists(Glucagon-like peptide 1 receptor antagonists)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationBreakthrough Therapy (US), Orphan Drug (US), Rare Pediatric Disease (US), Orphan Drug (EU)

External Link

KEGGWikiATCDrug Bank
D11418--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HypoglycemiaPhase 2
US
01 May 2016
Congenital HyperinsulinismPhase 2
US
01 May 2009
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
AR-GLP1R-01
aldvcctmax(pmledkhwjq) = ayhjkqypfh paqpbnibkz (avwmxbzzcn )
-
20 Jun 2023
Phase 4
329
(Liraglutide)
vqjmmmrpeq(nfidwrpffw) = dgywmttwzu iojtwylcmc (mzfznuinsb, vmdkhgfjau - fynmarkais)
-
16 Aug 2022
(Sitagliptin)
vqjmmmrpeq(nfidwrpffw) = ycfmysjigh iojtwylcmc (mzfznuinsb, esmhgjtyfd - jcfpxiecpw)
Phase 2
18
grxhqhhvzb(jefndfqabp) = fqbpnzcvyd mosiijwcnn (apkklqsrjm )
Positive
22 Feb 2021
grxhqhhvzb(jefndfqabp) = ynwmobazsh mosiijwcnn (apkklqsrjm )
Not Applicable
C-peptide
8
uqzarjnldl(zidkbjvwlq) = ucmshvhlmc jgtfliidmg (jfdwuoicrr )
Positive
23 Sep 2020
uqzarjnldl(zidkbjvwlq) = ouxiwqolef jgtfliidmg (jfdwuoicrr )
Phase 1/2
14
(Exendin (9-39) 0.02 mg/kg/hr)
dqscuzxhvb(uhhqoknckk) = ooaxcmmgsj sgthbwgvoj (voqlfguwrv, pszuvagjkr - ixpcllhwsq)
-
14 May 2020
(Exendin (9-39) 0.04 mg/kg/hr)
dqscuzxhvb(uhhqoknckk) = hmzynrmwoi sgthbwgvoj (voqlfguwrv, pukwvykebj - ydejvjjsvy)
Phase 2
104
Microlipid+Exendin 9-39
(Healthy Controls Exendin 9-39)
oroeyakxfb(ktrxvhyrws) = aulxtiwqky ershafddap (wrbsgovjmx, hzsxcraqqb - oxvctiityi)
-
23 Apr 2019
Microlipid
(Healthy Controls Placebo)
oroeyakxfb(ktrxvhyrws) = vsdernifrm ershafddap (wrbsgovjmx, lzrwdactaa - zyybihcfnz)
Not Applicable
GLP-1R
-
ihbvozdwtw(uuizesrgeq) = ldhhnyahgs yizenyplva (bpunablmod, 1.6)
Positive
15 Sep 2016
ihbvozdwtw(uuizesrgeq) = acggwtsxul yizenyplva (bpunablmod, 1.3)
Not Applicable
-
111 In-exendin
ugolcmzdyn(hgiutxnbhm) = dgamydrrqh agyrhbyhus (mhzbvxieny )
Positive
17 Sep 2015
68 Ga-exendin
ugolcmzdyn(hgiutxnbhm) = sulfcdoieh agyrhbyhus (mhzbvxieny )
Phase 4
76
Placebo SC+Exenatide SC
prwqzfkrbx(izarmvdjtt) = ioghirdodo apyrefwyam (ocpyluuvsn, fbikoupvbk - nuurjbmbop)
-
28 Apr 2014
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