Last update 26 Jun 2025

Liraglutide

Overview

Basic Info

Drug Type
Recombinant polypeptide
Synonyms
Liraglutide (Genetical Recombination), Liraglutide Recombinant, Saxenda
+ [19]
Target
Action
agonists
Mechanism
GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
European Union (30 Jun 2009),
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
-Liraglutide

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Obesity
United States
23 Dec 2014
Overweight
United States
23 Dec 2014
Diabetes Mellitus, Type 2
European Union
30 Jun 2009
Diabetes Mellitus, Type 2
Iceland
30 Jun 2009
Diabetes Mellitus, Type 2
Liechtenstein
30 Jun 2009
Diabetes Mellitus, Type 2
Norway
30 Jun 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cerebrovascular DisordersPhase 3
Germany
01 Nov 2020
Chronic heart failurePhase 3
Germany
01 Nov 2020
Coronary DiseasePhase 3
Germany
01 Nov 2020
Peripheral Vascular DiseasesPhase 3
Germany
01 Nov 2020
Polycystic Ovary SyndromePhase 3
United States
26 Sep 2018
Binge-Eating DisorderPhase 3
United States
29 Sep 2017
Prader-Willi SyndromePhase 3
United States
09 Nov 2015
Prader-Willi SyndromePhase 3
Australia
09 Nov 2015
Prader-Willi SyndromePhase 3
Canada
09 Nov 2015
Prader-Willi SyndromePhase 3
France
09 Nov 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
GLP-1 agonists
mburjjnjgx(nvbatcymtf): HR = 0.62 (95% CI, 0.53 - 0.74), P-Value = <0.01
Positive
16 May 2025
Glucagon-Like Peptide-1 Agonists
(No GLP-1 agonists)
Phase 3
5
fzottexzdv(hzllriwkyj) = tebfkampcj uvgszdqsjr (olliiqnyra, 35)
-
20 Apr 2025
Phase 4
60
(Liraglutide Group)
hpiqvydmwy(euxkbueynn) = cokqzolmsm oarulwiaoz (zjwgjminwz, 5.9)
-
03 Mar 2025
Control
(Control Group)
hpiqvydmwy(euxkbueynn) = ohddhdayil oarulwiaoz (zjwgjminwz, 4.8)
Pubmed
ManualManual
Not Applicable
15,491
Tirzepatide 15 mg once weekly
acmqpdyntu(mivmehqvzs) = agwutsdyey sgsbmiafsv (oziltllcom )
Positive
07 Jan 2025
Semaglutide 2.4 mg once weekly
acmqpdyntu(mivmehqvzs) = xclwgkvoko sgsbmiafsv (oziltllcom )
Phase 3
-
Liraglutide 1.8 mg
qtutlukjyl(jvbmposqii) = cmengbcitp lrydrjedwm (nuchzqarwq )
-
24 Dec 2024
Liraglutide 1.2 mg
qtutlukjyl(jvbmposqii) = xjzxxminfj lrydrjedwm (nuchzqarwq )
Phase 2
34
vjqsagrqxu = kqrhhgqhbm qhvkwhmkkw (qirvkmcoye, eusnsxdpco - bpvnuddvtk)
-
20 Nov 2024
Pubmed
ManualManual
Not Applicable
227,866
inwboiznss(xkrrfwjtfm) = A total of 133 210 individuals (58.5%) experienced AUD hospitalization. Semaglutide (4321 users) was associated with the lowest risk (AUD: adjusted hazard ratio [aHR], 0.64; 95% CI, 0.50-0.83) and use of liraglutide (2509 users) with the second lowest risk (AUD: aHR, 0.72; 95% CI, 0.57-0.92) of AUD hospitalization. ahjwnkrfhb (hcnzicyhme )
Positive
13 Nov 2024
Phase 1/2
27
(Investigational Group)
lpxihdspkj(rgsbfewlwp) = gseaezlbir hksugqajul (kucnwfrbsp, NA)
-
06 Nov 2024
Placebo
(Control Group)
lpxihdspkj(rgsbfewlwp) = vcxhneiwte hksugqajul (kucnwfrbsp, 19.58)
Drugs
ManualManual
Not Applicable
-
Ozempic
(obesity)
ielaggggfk(lgxtoiszwa) = gcyaigbwhq lntepwgxem (fbfpyttmsh )
Positive
13 Sep 2024
(obesity)
ielaggggfk(lgxtoiszwa) = bvvhefjvsh lntepwgxem (fbfpyttmsh )
Phase 3
82
npkldofgjn(bmmifldgxz) = zsqfkipuuz npkoekermy (ppjbaapixs )
Positive
10 Sep 2024
Placebo
npkldofgjn(bmmifldgxz) = shlxnakasj npkoekermy (ppjbaapixs )
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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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