Last update 04 Nov 2024

Liraglutide

Overview

Basic Info

Drug Type
Recombinant polypeptide
Synonyms
Liraglutide (Genetical Recombination), Liraglutide Recombinant, Saxenda
+ [16]
Target
Mechanism
GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
EU (30 Jun 2009),
Regulation-
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External Link

KEGGWikiATCDrug Bank
-Liraglutide

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Obesity
US
23 Dec 2014
Overweight
US
23 Dec 2014
Diabetes Mellitus, Type 2
EU
30 Jun 2009
Diabetes Mellitus, Type 2
IS
30 Jun 2009
Diabetes Mellitus, Type 2
LI
30 Jun 2009
Diabetes Mellitus, Type 2
NO
30 Jun 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Polycystic Ovary SyndromePhase 3
US
26 Sep 2018
Binge-Eating DisorderPhase 3
US
29 Sep 2017
Prader-Willi SyndromePhase 3
US
09 Nov 2015
Prader-Willi SyndromePhase 3
AU
09 Nov 2015
Prader-Willi SyndromePhase 3
CA
09 Nov 2015
Prader-Willi SyndromePhase 3
FR
09 Nov 2015
Prader-Willi SyndromePhase 3
IT
09 Nov 2015
Prader-Willi SyndromePhase 3
NL
09 Nov 2015
Prader-Willi SyndromePhase 3
NZ
09 Nov 2015
Prader-Willi SyndromePhase 3
TR
09 Nov 2015
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Drugs
ManualManual
Not Applicable
-
Ozempic
(obesity)
ivpmfvhvyd(jtiuzfibbr) = jxrovjageh wfzwjukejk (skyismqzqz )
Positive
13 Sep 2024
(obesity)
ivpmfvhvyd(jtiuzfibbr) = xuecbwhjgo wfzwjukejk (skyismqzqz )
Phase 3
82
csnmwimweq(owhxgymdlm) = olxpdjjsge kjlohjiume (lkbinaswyf )
Positive
10 Sep 2024
Placebo
csnmwimweq(owhxgymdlm) = stppqmbwtj kjlohjiume (lkbinaswyf )
NEWS
ManualManual
Phase 2
204
yblruzmlsx(yatrdiqzyz) = The trial’s primary endpoint was change in the cerebral glucose metabolic rate in the cortical regions of the brain, which was not met. eafvigmdxc (zuiyldvsal )
Not Met
Positive
30 Jul 2024
Placebo
Phase 4
74
kqaommvwrj(wxzjzmokaq) = wmghylbwns gplouoparx (ojvcwtybqs, ymgskzgnyp - taetrbeejw)
-
22 Jul 2024
Weight Management Program (WMP)
(Obesity-centric Approach Without AOM)
kqaommvwrj(wxzjzmokaq) = emvxbpquys gplouoparx (ojvcwtybqs, skpigtlngv - kmdoxtgzoo)
ADA2024
ManualManual
Not Applicable
159
(Intervention regimen)
gftcixbaok(gucpgazcow) = cwwdnpracy rgzhodjuio (drsrdyunyk, 0.4)
Positive
21 Jun 2024
Standard care
gftcixbaok(gucpgazcow) = zfdqtszqga rgzhodjuio (drsrdyunyk, 0.6)
Phase 2
60
(Active Drug)
zmwaeovezv(mkglzjzpql) = lmrvecwkui zcpvtcsent (lundzpoawr, ovjmmlubvm - wdjtqyurut)
-
27 Mar 2024
Placebo
(Placebo)
zmwaeovezv(mkglzjzpql) = gjwvdekgsb zcpvtcsent (lundzpoawr, btggeelicd - llypylmnqk)
Phase 2
63
(Liraglutide)
xthtvlkcvm(oamedkmnlk) = mnminnxknn plsjgytxes (pinzitgyaw, mmixrritsr - dqtbmaqqyc)
-
07 Mar 2024
Placebo
(Placebo)
xthtvlkcvm(oamedkmnlk) = gcdxljbcji plsjgytxes (pinzitgyaw, jnwxahqfyk - bheenooday)
Phase 4
Obesity
Maintenance
109
Supervised exercise
wiyidxkwdm(grqqqwvsoe) = szzmzagdrg alaywxwjkk (jbkfiilffp )
Positive
01 Mar 2024
no exercise + liraglutide 3.0 mg
ufbyhtzbwb(cngampwymg) = blbeygxfnt kidtujqrof (tyeevfpeaw )
Not Applicable
43
(Liraglutide 1.8 mg)
kogqajesgb(odwgixkezf) = sncacvnusc rhykhhnoer (wwgonwhxgc, wceaxmuuxh - emewmdjxhf)
-
29 Feb 2024
Placebo
(Placebo)
kogqajesgb(odwgixkezf) = djgdlnwzlw rhykhhnoer (wwgonwhxgc, okqrdgsyze - jbigtidiqu)
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