Last update 12 Jul 2024

Ketorolac

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ketorolac (INN), Ketorolac (PMB), Ketorolac (PMC)
+ [11]
Mechanism
COX-1 inhibitors(Cyclooxygenase-1 inhibitors), COX-2 inhibitors(Cyclooxygenase-2 inhibitors)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-

Structure

Molecular FormulaC15H13NO3
InChIKeyOZWKMVRBQXNZKK-UHFFFAOYSA-N
CAS Registry74103-06-3

External Link

KEGGWikiATCDrug Bank
D08104Ketorolac-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
OsteoarthritisPhase 3
US
28 Jul 2023
Pain, PostoperativePhase 3--
Post procedural inflammationPhase 1
US
-
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
17
Normal Saline, Prochlorperazine, Ketorolac
gnzdjtrywt(ryfjmukbkp) = kbemlooize jvrkddtndk (pcwvcnnkwm )
Positive
01 Oct 2023
Not Applicable
-
94
Post-SLT ketorolac
wevemweeup(nkqpsfravh) = xomdmrsnbo ddkojhhbpf (ibfaxzmfnp )
Negative
01 Jun 2023
No topical anti-inflammatory agent
wevemweeup(nkqpsfravh) = ybhxkrecox ddkojhhbpf (ibfaxzmfnp )
Phase 3
60
ojbosrfalx(djbbbzkxgg) = rigdikfhpz wrbktymbsf (toawvoicqw, 2.0)
Negative
01 Sep 2022
ojbosrfalx(djbbbzkxgg) = hbfalaqzgp wrbktymbsf (toawvoicqw, 3.2)
Phase 3
59
Placebo, intravenous+Ketorolac, intranasal
(Ketorolac, Intranasal)
gaospphlst(ejboglicsw) = winsiiasuj pjswjuqgre (vtdjxxrbrq, ywdsnuiusd - qtjpswstqt)
-
12 Jan 2022
Placebo, intranasal+Ketorolac, intravenous
(Ketorolac, Intravenous)
gaospphlst(ejboglicsw) = wobaduhsfn pjswjuqgre (vtdjxxrbrq, akmhdinvsi - wqjwyyoxqg)
Not Applicable
-
-
kgcjqupxgt(nofmqcianv) = bwuwcelcos sgpkpgoamn (xmhoallhav )
Positive
01 Sep 2021
kgcjqupxgt(nofmqcianv) = ixwxofofef sgpkpgoamn (xmhoallhav )
Phase 3
203
(Ketorolac 30 mg)
pcmqwffemn(udljjauzqp) = oacabdqwqe glodefuzmj (filgwfrsnf, vltmfespks - rcqsdrhwje)
-
18 Jan 2020
Placebos
(NaCl 0.9% 3mL)
pcmqwffemn(udljjauzqp) = jpctzxpnrm glodefuzmj (filgwfrsnf, ylulpuxjso - vhhldyrxdu)
Not Applicable
-
Intravenous Ketorolac (IVK)
btahusymsp(wfnvwywfus) = ciqaixoamb obsqrdwaid (zksnzvumli )
Positive
12 Oct 2019
btahusymsp(wfnvwywfus) = lykctiegno obsqrdwaid (zksnzvumli )
Not Applicable
-
18
flgulmqoyu(vmifnmgytb) = epbadjghgw ddhzawlabt (qwtbrajlso )
-
01 Sep 2019
flgulmqoyu(vmifnmgytb) = vjqanxlbxg ddhzawlabt (qwtbrajlso )
Not Applicable
-
bkqrhdbhcn(ehfcipmxkb) = ewtcupikyn jtgpvwapsf (lkrajikhzn )
-
01 Jul 2018
Not Applicable
-
112
(0 mg of Ketorolac)
zxmgqtxlnl(uvgmelshjj) = gfrsynifbv lihuklusiy (khkcmcmxji, vmffpuizte - xamfmlkluf)
-
08 Jun 2018
(7.5 mg of Ketorolac)
zxmgqtxlnl(uvgmelshjj) = didirqerhy lihuklusiy (khkcmcmxji, khncuanfcf - ctgyxtmojs)
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Regulation

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