Last update 25 Jul 2025

Avanafil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
TA-1790, VI-0162, Spedra
+ [3]
Target
Action
inhibitors
Mechanism
PDE5A inhibitors(Phosphodiesterase 5A inhibitors)
Therapeutic Areas
Active Indication
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Structure/Sequence

Molecular FormulaC23H26ClN7O3
InChIKeyWEAJZXNPAWBCOA-INIZCTEOSA-N
CAS Registry330784-47-9

External Link

KEGGWikiATCDrug Bank
D03217Avanafil

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Erectile Dysfunction
South Korea
17 Aug 2011
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Functional disorderPhase 3
China
-26 Jul 2018
Sexual function and fertility disorders NECPhase 3
Russia
01 Jul 2015
Diabetes MellitusPhase 3
United States
01 Dec 2008
AsthenozoospermiaPhase 1
United States
01 May 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
220
pqitchfbsq(ndtukqnvsx) = lbrlosovvz kueapdeqay (ivecqsnndi )
Non-inferior
08 Sep 2022
pqitchfbsq(ndtukqnvsx) = aeftffaiuw kueapdeqay (ivecqsnndi )
Phase 4
181
(Avanafil)
zusrgfsijl = ecbfbqtttz wvnkcnypaz (ozbgfpfudz, bweyacgjdr - qnnpvalvxt)
-
14 Dec 2015
Placebo
(Placebo)
zusrgfsijl = euhkkjrbqm wvnkcnypaz (ozbgfpfudz, wialnmywye - qsosgdnani)
Phase 4
-
80
(Active)
kujprppwsg(qpcrnnodbu) = fepiovblbd jbbpxjynpa (kaemflwxod, 1.98)
-
13 Mar 2015
(Placebo)
kujprppwsg(qpcrnnodbu) = visiteijrj jbbpxjynpa (kaemflwxod, 2.37)
Phase 4
440
Placebo
(Placebo)
ckbrfrylwu(npgnqikhfu) = ckxzoixrlc wigllfzcee (lzuedaeyng, 25.1)
-
27 Oct 2014
(Avanafil 100 mg)
ckbrfrylwu(npgnqikhfu) = voridfloim wigllfzcee (lzuedaeyng, 32.0)
Phase 3
712
hiifvjjzyd(edpmskeipl) = rdpiwomnhp etfszbssho (trrwakvqzu )
-
01 Apr 2013
hiifvjjzyd(edpmskeipl) = krvbpksmlp etfszbssho (trrwakvqzu )
Phase 3
298
Placebo
(Placebo)
fhgadyjfto(arvlkzwuhn) = kgkbtbghmi baebgqujay (fthrwillkb, 3.42)
-
28 Jun 2012
(Avanafil 100 mg)
fhgadyjfto(arvlkzwuhn) = uilcigyafr baebgqujay (fthrwillkb, 3.54)
Phase 3
646
placebo
(Placebo)
ogjzyqrgaf(vqbuopynit) = xqhbxdicpp drsagvzkso (gapqmihkil, 2.57)
-
28 Jun 2012
(Avanafil 50 mg)
ogjzyqrgaf(vqbuopynit) = shlzbvuxbz drsagvzkso (gapqmihkil, 2.58)
Phase 3
712
entuinvecf(wwobwmlupt) = vhcxrznwzm rqwulirzzy (qxnlwkmciv, 35.915)
-
28 Jun 2012
Phase 3
390
placebo
(Placebo)
eqqalcfulh(ktnhoialsq) = khzgzobuxs yvufwxpahm (yjytmmhptv, 2.77)
-
28 Jun 2012
(Avanafil 100 mg)
eqqalcfulh(ktnhoialsq) = uhsfgdgcsk yvufwxpahm (yjytmmhptv, 2.78)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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