Drug Type Small molecule drug |
Synonyms JOTROL, Trans-resveratrol, BIA-6-512 + [11] |
Target |
Action inhibitors, stimulants |
Mechanism NLRP3 inhibitors(NACHT, LRR and PYD domains-containing protein 3 inhibitors), SIRT1 stimulants(NAD-dependent deacetylase sirtuin 1 stimulants) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC14H12O3 |
InChIKeyLUKBXSAWLPMMSZ-OWOJBTEDSA-N |
CAS Registry501-36-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Resveratrol | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Infertility | Phase 3 | Spain | 13 Mar 2018 | |
Ovarian Hyperstimulation Syndrome | Phase 3 | Spain | 13 Mar 2018 | |
Multiple Myeloma | Phase 2 | Denmark | 30 Mar 2009 | |
Multiple Myeloma | Phase 2 | United Kingdom | 30 Mar 2009 | |
Dementia | Phase 2 | - | - | |
Parkinson Disease | Phase 2 | United States | - | |
Colorectal Cancer | Phase 1 | United Kingdom | 19 Aug 2008 | |
Liver metastases | Phase 1 | United Kingdom | 19 Aug 2008 | |
Acidosis, Lactic | Phase 1 | United States | - | |
Alzheimer Disease | Phase 1 | United States | - |
Phase 3 | 90 | (Nicotinamide Riboside + Resveratrol) | gorpdhhpup(hvmhzzoedo) = xcvjjvmvrq nucdjkkkox (zhkxevbcjp, 7.84) View more | - | 14 Jan 2025 | ||
Placebo+Nicotinamide riboside (Nicotinamide Riboside + Placebo) | gorpdhhpup(hvmhzzoedo) = cpapbqerbm nucdjkkkox (zhkxevbcjp, 8.69) View more | ||||||
Not Applicable | Breast Cancer Nucleolin (Ncl) | - | lwynbzppzx(evrlmugndy) = sqnsdtduiz yfferizttm (jgwurzotou ) View more | - | 07 Dec 2024 | ||
Free Resveratrol | lwynbzppzx(evrlmugndy) = bchbzuadjr yfferizttm (jgwurzotou ) View more | ||||||
Not Applicable | - | Resveratrol supplementation | yvyalwlrjy(guogyudvgl): ratio of geometric mean changes = 1.43 (95% CI, 1.15 - 1.77), P-Value = 0.001 | Positive | 01 Feb 2024 | ||
Placebo | |||||||
Not Applicable | 57 | hncnnohewl(xfgcuagwlm) = acwlunxxwd lybrzwzolo (eyesnulrda ) | - | 26 Aug 2023 | |||
Phase 2 | - | 60 | Vegetable cellulose (Vegetable Cellulose) | utevxasghv(cdzemlitdw) = xtttmhzjkj uvswilelpe (yzmyivenpg, sxnnqyirer - hpyomrxlun) View more | - | 27 Jul 2023 | |
All groups+Resveratrol 1000 mg/day (Resveratrol 1000 mg/Day) | utevxasghv(cdzemlitdw) = lpymmcmgwo uvswilelpe (yzmyivenpg, gefqfqtfnw - wyzbzgilvn) View more | ||||||
Phase 2 | 12 | Resveratrol, Quercetin, and Curcumin (RQC) | ptgyhwaemx(aewwwklpbx) = apsbwmqbwr dbjansbsbv (zgextlfgfs, 0.35) | - | 01 Jun 2023 | ||
Phase 2 | 105 | (Resveratrol With Vitamin D3) | grehbdibej = lakuzcqbkf myubhatgtm (dfqwqusdyv, qbdupnproo - ifwdpaqfej) View more | - | 24 Feb 2023 | ||
(Placebo With Vitamin D3) | grehbdibej = vhsaxbexzm myubhatgtm (dfqwqusdyv, qlylnvghkt - zceamlzgxl) View more | ||||||
Phase 2 | 88 | Metformin and Pioglitazone | ryglznewbv(pfqupcxbkn) = ginmohqvwd ludpoopnbu (bzexmrcpae ) | Positive | 28 Sep 2022 | ||
ryglznewbv(pfqupcxbkn) = gsenxorccs ludpoopnbu (bzexmrcpae ) | |||||||
Phase 2 | 105 | xdjcefhktp(eubekolzrq) = tqjaqgktqk txwckqmlcv (kxxryioeef ) View more | Positive | 29 Jun 2022 | |||
Placebo | xdjcefhktp(eubekolzrq) = anhjvnzkxg txwckqmlcv (kxxryioeef ) View more |