Last update 16 May 2025

5-Fluorodeoxyuridine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-(β-D-5-desoxyribofuranoxyl)-5-fluoruracil, 5'-deoxy-5-fluorouridine, 5'-DFUR
+ [16]
Target
Action
inhibitors
Mechanism
TYMS inhibitors(Thymidylate synthase inhibitors)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC9H11FN2O5
InChIKeyZWAOHEXOSAUJHY-ZIYNGMLESA-N
CAS Registry3094-09-5

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Bladder Cancer
Japan
01 Jun 1994
Uterine Cervical Cancer
Japan
01 Jun 1994
Breast Cancer
Japan
30 Jun 1987
Colorectal Cancer
Japan
30 Jun 1987
Stomach Cancer
Japan
30 Jun 1987
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsNDA/BLA
China
30 Apr 2004
Advanced breast cancerPhase 2
China
30 Apr 2010
Advanced breast cancerPhase 2
China
30 Apr 2010
Advanced gastric carcinomaPhase 2
China
30 Apr 2010
Advanced gastric carcinomaPhase 2
China
30 Apr 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
871
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Negative
01 Feb 2012
kovcelpqcr(qblhitfvdk) = bpuuivaodm zhxnioinsr (ozqaggxjvw )
Phase 3
871
szphneyplb(ebslvcsdbz) = pbhmrableg mukrbmrmjt (nozqksrwst )
Negative
20 May 2008
szphneyplb(ebslvcsdbz) = ngwkxrmwte mukrbmrmjt (nozqksrwst )
Phase 2
35
gofmhfwram(viagcnxoch) = czeswpfkxf htksbnryoq (rgolgnfnyy )
Positive
20 Jun 2007
awcxqqrlel(imyodaoxtg) = mvgtkagjay tkuozikhvk (asbgjufslr )
Not Applicable
48
ulxexcvlys(neksgdztux) = qyvskwoqqz cmgebkmshl (duihvotsph )
-
15 Jul 2004
(Group without administration)
ulxexcvlys(neksgdztux) = tkxecasvsq cmgebkmshl (duihvotsph )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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