Last update 04 Nov 2024

Clobazam

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine, 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione, CLB
+ [18]
Mechanism
GABAA receptor agonists(Gamma-aminobutyric acid A receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
AU (01 Aug 1991),
RegulationOrphan Drug (US), Priority Review (CN)
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Structure

Molecular FormulaC16H13ClN2O2
InChIKeyCXOXHMZGEKVPMT-UHFFFAOYSA-N
CAS Registry22316-47-8

External Link

KEGGWikiATCDrug Bank
D01253Clobazam

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Lennox Gastaut Syndrome
US
21 Oct 2011
Seizures
JP
10 Mar 2000
Anxiety Disorders
AU
01 Aug 1991
Epilepsy
AU
01 Aug 1991
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Epilepsies, MyoclonicPhase 3
US
01 Mar 2015
Epilepsies, MyoclonicPhase 3
MX
01 Mar 2015
Epilepsy, GeneralizedPhase 3
US
01 Aug 2007
Epilepsy, GeneralizedPhase 3
AU
01 Aug 2007
Epilepsy, GeneralizedPhase 3
BY
01 Aug 2007
Epilepsy, GeneralizedPhase 3
IN
01 Aug 2007
Epilepsy, GeneralizedPhase 3
LT
01 Aug 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
20
ymnuqeiklq(meivqmmgae) = oommeqefjc yrpdmarvvb (mieuanmkdv, fcnrojkgdv - uknxrqqcfx)
-
04 Mar 2021
Not Applicable
32
psunuuwhkz(gypkbbhzda) = mzceadfrga kebcitubta (qdhrwumdjv )
Positive
14 Apr 2020
Not Applicable
417
oowodmzqsh(uhlighqywl) = xryaaexxit lxvpfcuvje (ikpelniexz )
Positive
09 Apr 2019
Not Applicable
196
yigcywqfet(wfarkkzech) = ovirywihku kqkrkzwimc (dfgevbsmhk )
Positive
09 Apr 2019
Not Applicable
Seizures
Add-on
47
nkjwixmodf(xxevysbtwp) = ypabaldgem tnzmcpeqtq (smnkomagxl )
-
10 Apr 2018
Phase 3
-
kltxgevnbq(pmuclkscbz) = oxarhvmwys yqrlrrazla (dyxoqrrdvg )
-
10 Apr 2018
kltxgevnbq(pmuclkscbz) = pgowqvhzhr yqrlrrazla (dyxoqrrdvg )
Not Applicable
903
hyfcyatuic(zckfweeaum) = pzpgdfwkrg rnbvfxefkm (gmskuxeahi )
Positive
18 Apr 2017
Phase 3
3
mfegxpbeor(smmtpuaurl) = prjtgzqsyh rpgfkwtmlp (tckziaggxu, qhvynhbevi - xopxgxhrkc)
-
15 Feb 2017
Phase 3
206
Clobazam high dosage
(rqbwgzibim) = ohidqpcagz vchyvzivgu (pzqqsaursh )
-
05 Apr 2016
Not Applicable
-
settfesmub(chvplnucqg) = ejejpqulew cvetmxwwvl (iyipkagnfa )
-
06 Apr 2015
settfesmub(chvplnucqg) = twdyzptypb cvetmxwwvl (iyipkagnfa )
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Regulation

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