Drug Type Bispecific antibody |
Synonyms Anti-HER3/EGFR DAF, Duligotuzumab, Duligotuzumab (USAN) + [4] |
Target |
Action antagonists |
Mechanism EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists), HER3 antagonists(Receptor tyrosine-protein kinase erbB-3 antagonists) |
Therapeutic Areas |
Active Indication- |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhasePendingPhase 2 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D11750 | Duligotuzumab(Genentech, Inc.) | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
KRAS Wild-type Colorectal Cancer | Phase 2 | United States | 01 Oct 2012 | |
KRAS Wild-type Colorectal Cancer | Phase 2 | Australia | 01 Oct 2012 | |
KRAS Wild-type Colorectal Cancer | Phase 2 | Belgium | 01 Oct 2012 | |
KRAS Wild-type Colorectal Cancer | Phase 2 | France | 01 Oct 2012 | |
KRAS Wild-type Colorectal Cancer | Phase 2 | Germany | 01 Oct 2012 | |
KRAS Wild-type Colorectal Cancer | Phase 2 | Italy | 01 Oct 2012 | |
KRAS Wild-type Colorectal Cancer | Phase 2 | New Zealand | 01 Oct 2012 | |
KRAS Wild-type Colorectal Cancer | Phase 2 | Romania | 01 Oct 2012 | |
KRAS Wild-type Colorectal Cancer | Phase 2 | Spain | 01 Oct 2012 | |
KRAS Wild-type Colorectal Cancer | Phase 2 | United Kingdom | 01 Oct 2012 |
Phase 1 | Neoplasms KRAS Mutation | 23 | aywqnkyior(pxjpsjggak) = daohuizlud ifdhscacta (kinlborlqo ) View more | Negative | 01 Sep 2017 | ||
Phase 1 | Squamous Cell Carcinoma of Head and Neck First line | 24 | nhhspmplxj(lqnevdxnpw) = fraqrnypwk jyyxqzypzo (tnpnqnqddr ) | Positive | 15 Dec 2016 | ||
nhhspmplxj(lqnevdxnpw) = rvgdjoaflq jyyxqzypzo (tnpnqnqddr ) | |||||||
Phase 2 | Squamous Cell Carcinoma NRG1 | ERBB3 | HPV | 121 | mbklahialy(mwkygpdezs) = hdvsfxtxii tdczvduzub (ayqhulfmqd ) View more | Negative | 31 Oct 2016 | ||
mbklahialy(mwkygpdezs) = vlakwlntqs tdczvduzub (ayqhulfmqd ) View more | |||||||
Phase 1 | - | MEHD7945A (MEHD) | zbkflosuak(hwshxxpbig) = exitrbjsxb lbslgqhcfq (ecwippeceu ) View more | - | 20 May 2012 |