Drug Type Small molecule drug |
Synonyms (SP-4-3)-Amminedichloro(2-methylpyridine)platinium, Picoplatin (INN/USAN/BAN), AMD 473 + [8] |
Target |
Action inhibitors |
Mechanism DNA inhibitors(DNA inhibitors), DNA alkylating agents |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
RegulationOrphan Drug (United States) |
Molecular FormulaC6H10Cl2N2Pt |
InChIKeyIIMIOEBMYPRQGU-UHFFFAOYSA-L |
CAS Registry181630-15-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D08968 | Picoplatin | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Small Cell Lung Cancer | Phase 3 | Argentina | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | Belarus | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | Bosnia and Herzegovina | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | Bulgaria | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | Chile | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | Croatia | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | Hungary | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | India | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | Latvia | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | Montenegro | 01 Apr 2007 |
Phase 3 | 401 | Picoplatin + BSC | wvwwuqukjk(hgdutermdt) = gibtvjjsdy buxxmqqzhe (ixtfjmwdjn, CI 19 - 25) View more | Positive | 20 May 2010 | ||
(BSC) | wvwwuqukjk(hgdutermdt) = bxlbheesig buxxmqqzhe (ixtfjmwdjn, CI 16 - 24) View more | ||||||
Phase 2 | Colorectal Cancer First line | 101 | klznnmnbtd(xkrndrltqc) = Neurotoxicity was less frequent and less severe in the FOLPI arm compared to the FOLFOX arm cdnkhziumq (gkguvgclct ) | - | 20 May 2009 | ||
modified FOLFOX-6 (FOLFOX) | |||||||
Phase 2 | 32 | tvyezauzsx(tyfmloteav) = epjfyfufyt fnmxpevjpm (qyzvltaauo ) | - | 20 May 2009 | |||
Phase 1 | - | yxndmcypjz(xwmkrzpysd) = kgkbhxcihy eoffcllwlj (taeiwrjoju, 23) View more | - | 01 May 2009 | |||
yxndmcypjz(xwmkrzpysd) = hsfpjcgzwj eoffcllwlj (taeiwrjoju, 28) View more | |||||||
Phase 1 | 73 | Pico every 4 wks | jaeprsvqfv(velfdtaiaa) = goeodtugyg frpiuebjde (mgfsljfwsw ) | - | 01 May 2009 | ||
Pico every 2 wks | fgbjdkxacn(acoecjciwg) = ppjasimvuq ppvtpmjjja (mlcgdcmkwf ) | ||||||
Phase 2 | Colorectal Cancer First line | 59 | pxcwmhzmld(jcrumycssv) = wcmtlffmwx pifzauwvct (ptsovnobih ) | - | 20 May 2008 | ||
Phase 1 | - | yatrfochwp(rmhqgrnkhs) = wgsqektpit oyukgeximc (mxokemxpqn ) | - | 20 May 2008 | |||
Phase 2 | 30 | upqpammcye(xipijqbirr) = cpdninbwhr kksjpdaogt (mhaexqanhk ) View more | - | 20 May 2008 | |||
Phase 2 | Small Cell Lung Cancer Second line | 77 | xxbcrumdcz(ewjyrskkuf) = zixicgtwuf oukxurirbu (eymkqlhhky ) View more | - | 20 Jun 2007 | ||
Phase 1 | 23 | bcscisttxb(dqtemczloh) = hgvuchdnji wqbrpogrua (gqnfhkxbiw ) | - | 20 Jun 2007 | |||
bcscisttxb(dqtemczloh) = kjvkgwezwi wqbrpogrua (gqnfhkxbiw ) |