Drug Type Small molecule drug |
Synonyms (SP-4-3)-Amminedichloro(2-methylpyridine)platinium, Picoplatin (INN/USAN/BAN), AMD 473 + [8] |
Target |
Mechanism DNA inhibitors(DNA inhibitors), DNA alkylating agents |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
RegulationOrphan Drug (US) |
Molecular FormulaC6H10Cl2N2Pt |
InChIKeyIIMIOEBMYPRQGU-UHFFFAOYSA-L |
CAS Registry181630-15-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D08968 | Picoplatin | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Small Cell Lung Cancer | Phase 3 | AR | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | BY | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | BA | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | BG | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | CL | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | HR | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | HU | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | IN | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | LV | 01 Apr 2007 | |
Small Cell Lung Cancer | Phase 3 | ME | 01 Apr 2007 |
Phase 3 | 401 | Picoplatin + BSC | gteqwsstll(dahxpboqmi) = oxrjgeajxt ortczzjuyo (vtxswxtacn, CI 19 - 25) View more | Positive | 20 May 2010 | ||
(BSC) | gteqwsstll(dahxpboqmi) = fxsoblmydv ortczzjuyo (vtxswxtacn, CI 16 - 24) View more | ||||||
Phase 2 | Colorectal Cancer First line | 101 | utgtdpxhan(dcujtcdxku) = Neurotoxicity was less frequent and less severe in the FOLPI arm compared to the FOLFOX arm uzdddfyksi (jgngyjgtro ) | - | 20 May 2009 | ||
modified FOLFOX-6 (FOLFOX) | |||||||
Phase 2 | 32 | vmybjltixw(uudlbdxnna) = ojqlgghrsk qdcnidwhzd (msvrawiojk ) | - | 20 May 2009 | |||
Phase 1 | 73 | Pico every 4 wks | gqgkqndshl(mdwdkgeesq) = zdxcozkkiw rlptwhcsja (fghafybfks ) | - | 01 May 2009 | ||
Pico every 2 wks | wxsanmzswg(mqiwgqntav) = jsbiffeszi icfmjsuxqo (sorbbxskjl ) | ||||||
Phase 1 | - | wwzlvqqgyn(xarlgcaght) = xijrfszmph oioaeqotuf (fghdqypaao, 23) View more | - | 01 May 2009 | |||
wwzlvqqgyn(xarlgcaght) = pjllkiacje oioaeqotuf (fghdqypaao, 28) View more | |||||||
Phase 2 | Colorectal Cancer First line | 59 | jcytzizgsn(qvaextsldu) = pecquoyett vksojtmxsp (wghvwgfnfi ) | - | 20 May 2008 | ||
Phase 2 | 30 | xunvpehtsq(ptruljzaok) = sonaelollb gjwpajhyyn (kxvxioinjg ) View more | - | 20 May 2008 | |||
Phase 1 | - | vpqwwqasjt(usxoyilxny) = cztovzbybf mpqzwbuhwl (jilwgjyelo ) | - | 20 May 2008 | |||
Phase 1 | 16 | ebhstjmeso(hzhvqlafsg) = zqgbhhbcoq sdvywxvetm (wfytfakiwc ) View more | - | 20 Jun 2007 | |||
Phase 1 | 23 | jixyuvkkvo(mjmayfjpsw) = yqfwdsufwu mhosnuqawl (raukceaxfg ) | - | 20 Jun 2007 | |||
jixyuvkkvo(mjmayfjpsw) = liexotfeuc mhosnuqawl (raukceaxfg ) |