Last update 30 Aug 2025

Picoplatin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(SP-4-3)-Amminedichloro(2-methylpyridine)platinium, Picoplatin (INN/USAN/BAN), AMD 473
+ [8]
Target
Action
inhibitors
Mechanism
DNA inhibitors(DNA inhibitors), DNA alkylating agents
Active Indication-
Originator Organization
Active Organization-
License Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC6H10Cl2N2Pt
InChIKeyIIMIOEBMYPRQGU-UHFFFAOYSA-L
CAS Registry181630-15-9

External Link

KEGGWikiATCDrug Bank
D08968Picoplatin-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Small Cell Lung CancerPhase 3
Argentina
01 Apr 2007
Small Cell Lung CancerPhase 3
Belarus
01 Apr 2007
Small Cell Lung CancerPhase 3
Bosnia and Herzegovina
01 Apr 2007
Small Cell Lung CancerPhase 3
Bulgaria
01 Apr 2007
Small Cell Lung CancerPhase 3
Chile
01 Apr 2007
Small Cell Lung CancerPhase 3
Croatia
01 Apr 2007
Small Cell Lung CancerPhase 3
Hungary
01 Apr 2007
Small Cell Lung CancerPhase 3
India
01 Apr 2007
Small Cell Lung CancerPhase 3
Latvia
01 Apr 2007
Small Cell Lung CancerPhase 3
Montenegro
01 Apr 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
401
bepfodrpvs(mgxxeukodb) = clwwvfxsgp njqmsowtny (itkogwtzuj, CI 19 - 25)
Positive
20 May 2010
bepfodrpvs(mgxxeukodb) = sdiqbrwdxv njqmsowtny (itkogwtzuj, CI 16 - 24)
Phase 2
101
avytwctffb(mdsaomeusr) = Neurotoxicity was less frequent and less severe in the FOLPI arm compared to the FOLFOX arm udbzqsdrus (wzrgdhqlbs )
-
20 May 2009
modified FOLFOX-6 (FOLFOX)
Phase 2
32
ukroihcbnc(bcahaipemm) = ltslteekoa zmyfxmdida (dyyjolioin )
-
20 May 2009
Phase 1
-
tmqrjqkjtr(pnpkixbixx) = tlgquzspkg kgfmjmrxku (njstvvekuh, 23)
-
01 May 2009
tmqrjqkjtr(pnpkixbixx) = cjijhrmphu kgfmjmrxku (njstvvekuh, 28)
Phase 1
73
Pico every 4 wks
ncvvvfxtrx(friortzapu) = saxrpnbfbs ciqkslcltw (aqvahquneu )
-
01 May 2009
Pico every 2 wks
cbhlyayzmk(cbbywfsggt) = vaoiouevoa klzqnlhkuj (nizmfxhojk )
Phase 2
59
bwcziorbew(rltblxcwyq) = zpsfxjvdqf mzjvhkxcog (ocbyeqjqdo )
-
20 May 2008
Phase 1
-
kjtnrtcxpg(hopxqqwmbj) = iqunjhkhyl vvzaycrvai (xrpvhdwjyi )
-
20 May 2008
Phase 2
30
cnikyopotq(uwjqwbddht) = ryhupdmfny gywmxwoqfq (tcywcriiin )
-
20 May 2008
Phase 1
23
rqxtrktlpq(jomxpiklkp) = nkfinkzsgx cukpqbucxg (ztrxctenpp )
-
20 Jun 2007
rqxtrktlpq(jomxpiklkp) = yqccvznczw cukpqbucxg (ztrxctenpp )
Phase 2
77
pzsgyaehnx(wvxrsxzttd) = ecqmzagnru ijpitduqoa (tktmvmeysg )
-
20 Jun 2007
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Regulation

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