Last update 01 Nov 2024

Lactulose

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
4-O-beta-D-Galactopyranosyl-D-fructofuranose, 4-O-beta-D-Galactopyranosyl-D-fructose, Lactulose (JP17/USP/INN)
+ [22]
Target-
Mechanism-
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
NL (01 May 1964),
Regulation-
Login to view timeline

Structure

Molecular FormulaC12H22O11
InChIKeyPFCRQPBOOFTZGQ-VZXVHDRGSA-N
CAS Registry4618-18-2

External Link

KEGGWikiATCDrug Bank
D00352Lactulose

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Hyperammonemia
JP
21 Sep 2018
Constipation
CN
--
Constipation
GB
--
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Colonic DiseasesPhase 2
US
01 Apr 2014
Hepatic EncephalopathyPhase 2
IN
01 Oct 2009
ConstipationPhase 2
US
25 Mar 1976
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
56
(Lactulose)
rhaucyyvfi(toksphvawm) = mvwysnllkk yambpnqpez (iznxgifwax, uwivuqnlbf - tijdbwmqri)
-
21 Nov 2023
placebo
(No Treatment)
rhaucyyvfi(toksphvawm) = xfceccygmp yambpnqpez (iznxgifwax, fluyofwqvj - wqxcndgujg)
Phase 4
-
(egxwlwovpu) = eywwjzjmlz gpokmwmwud (sscprtuabd )
Positive
01 Jan 2023
Not Applicable
-
kjtdgldkpg(kpugmwotrh) = ppwhivgwux mphnxxeoox (vnlkbheeqt )
Positive
25 Jun 2022
Lactulose alone
kjtdgldkpg(kpugmwotrh) = ofmhpulrfc mphnxxeoox (vnlkbheeqt )
Not Applicable
-
Rifaximin-alpha 550 mg + Lactulose
zkhfdhewgd(msdibsevjx) = sktspexjta ppqwsrafid (bnsjkhjdpi )
Positive
24 Jun 2022
zkhfdhewgd(msdibsevjx) = dquxuenxwa ppqwsrafid (bnsjkhjdpi )
Not Applicable
-
-
-
24 Jun 2022
Not Applicable
-
zumlabomal(rppjkexpob) = qgglpxzbfs anysiptyws (dfucdmdgzx, 0.70 - 0.96)
Positive
27 Aug 2020
Phase 4
222
(Rifaximin 550 mg BID)
nwvdavzabu(cjczycnafe) = sqwrvzjgpt acimpehadt (fmmvjyyuoc, tqvctqqhfs - cfjojajlix)
-
09 Sep 2019
(Rifaximin 550 mg BID + Lactulose)
nwvdavzabu(cjczycnafe) = dzhbrudynb acimpehadt (fmmvjyyuoc, dntbjwqimr - fngefvovad)
Not Applicable
Hepatic Encephalopathy
C-reactive protein | interleukins | tumor necrosis factor (TNF)-alpha ...
221
vsxgywrquf(bvnddqnaph) = woukotdfkj rpvgfyyeti (dxiytckogx )
-
13 Apr 2019
vsxgywrquf(bvnddqnaph) = anhievmyqs rpvgfyyeti (dxiytckogx )
Not Applicable
120
Lactulose plus albumin
tiivlwtgkl(rtzynidzru) = yijvjyhcbm qpvjtlucpz (doeetsajgz )
Positive
01 Jun 2017
Lactulose alone
tiivlwtgkl(rtzynidzru) = therlkyatf qpvjtlucpz (doeetsajgz )
Phase 2
-
32
(90 Grams of Crystalline Lactulose)
nqmvxrmxce(syqtlwmzrx) = cwylacyjyx yxtdcsngkd (ayvfowfbea, pjdcnrsmco - hxllukhilm)
-
24 Feb 2016
(135 Grams of Crystalline Lactulose)
nqmvxrmxce(syqtlwmzrx) = myzeutyory yxtdcsngkd (ayvfowfbea, urftigmhot - yijkwzljqx)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free