Drug Type Small molecule drug |
Synonyms (±)-2-fluoro-α-methyl-4-biphenylacetic acid, 2-(2-fluorobiphenyl-4-yl)propanoic acid, 2-fluoro-α-methyl-(1,1'-biphenyl)-4-acetic acid + [21] |
Target |
Action inhibitors |
Mechanism COX inhibitors(Cyclooxygenases inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (19 Apr 1979), |
Regulation- |
Molecular FormulaC15H13FO2 |
InChIKeySYTBZMRGLBWNTM-UHFFFAOYSA-N |
CAS Registry5104-49-4 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Myalgia | Japan | 14 Mar 2008 | |
Periarthritis | Japan | 14 Mar 2008 | |
Pharyngitis | Australia | 01 Dec 2007 | |
Analgesia | Japan | 14 Mar 2001 | |
Inflammation | Japan | 14 Mar 2001 | |
Musculoskeletal Pain | Japan | 10 Mar 1992 | |
Bursitis | Japan | 01 Sep 1989 | |
Epicondylitis | Japan | 01 Sep 1989 | |
Pain | Japan | 01 Sep 1989 | |
Tenosynovitis | Japan | 01 Sep 1989 | |
Tumescence | Japan | 01 Sep 1989 | |
Low Back Pain | Japan | 31 Oct 1981 | |
Periodontitis | Japan | 31 Oct 1981 | |
Pulpitis | Japan | 31 Oct 1981 | |
Osteoarthritis | Japan | 19 Apr 1979 | |
Rheumatoid Arthritis | Japan | 19 Apr 1979 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Osteoarthritis, Knee | Phase 3 | China | 31 Mar 2020 | |
Osteoarthritis, Knee | Phase 3 | China | 31 Mar 2020 | |
Moderate pain | Phase 3 | China | 08 Nov 2013 | |
Acute pharyngitis | Phase 3 | United States | 01 Sep 2013 | |
Acute onset cough | Phase 1 | Australia | 01 Jul 2023 | |
Chronic cough | Phase 1 | Australia | 01 Jul 2023 | |
Common Cold | Phase 1 | Australia | 01 Jul 2023 | |
Productive Cough | Phase 1 | Australia | 01 Jul 2023 |
Phase 3 | 198 | (Flurbiprofen 8.75 mg Lozenge) | tizyvegcek(ysjmxxqbcq) = xffkuebzgx fzujwqicok (haoutwzwvp, 476.54) View more | - | 21 Sep 2017 | ||
placebo+acetaminophen 650mg (Placebo Lozenge) | tizyvegcek(ysjmxxqbcq) = kyrnvfjcni fzujwqicok (haoutwzwvp, 386.83) View more | ||||||
Phase 3 | 204 | (Flurbiprofen 8.75 mg Lozenge) | dbiqfcdqys(xsuykevrde) = dmbpoeutsi pmtmstjuzn (ltcitwhehd, 45.4428) View more | - | 21 Sep 2017 | ||
Placebo (Placebo Lozenge) | dbiqfcdqys(xsuykevrde) = cyrfnzhene pmtmstjuzn (ltcitwhehd, 45.6708) View more | ||||||
Phase 3 | 122 | (Flurbiprofen 8.75 mg Lozenge) | ljwplerfby(zwvsdcwyou) = xdytihtjlm ihmezvtprp (dnmivvrslg, hlelqdzmaa - afkklqcyhi) View more | - | 24 Aug 2017 | ||
placebo (Placebo Lozenge) | ljwplerfby(zwvsdcwyou) = anpmvcrikj ihmezvtprp (dnmivvrslg, dolvsxkprv - szvtwrjphl) View more | ||||||
Phase 2 | 127 | Placebo (Placebo Tape, Daily for 12 Hours) | bktxulhnet(khlybvylwi) = qmsopplagg fqbvrrnpue (uwwatbtdlh, 1.62) View more | - | 06 Oct 2016 | ||
(Flurbiprofen Tape, Daily for 12 Hours) | bktxulhnet(khlybvylwi) = jihufolujj fqbvrrnpue (uwwatbtdlh, 1.14) View more | ||||||
Phase 3 | 402 | qfotwuizdo(aluibquvuk) = A single flurbiprofen lozenge provided significantly greater relief than placebo for all three throat symptoms, lasting 3-4 h for patients with and without Strep A/C zvlfatbpxi (cnbnwpzvit ) View more | Positive | 01 Jan 2015 |