Last update 09 May 2025

Latanoprost

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
L-PPDS, AL-37807, AR-202
+ [28]
Target
Action
agonists
Mechanism
PTGFR agonists(Prostanoid FP receptor agonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (05 Jun 1996),
Regulation-
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Structure/Sequence

Molecular FormulaC26H40O5
InChIKeyGGXICVAJURFBLW-CEYXHVGTSA-N
CAS Registry130209-82-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Glaucoma
Japan
12 Mar 1999
Glaucoma, Open-Angle
United States
05 Jun 1996
Ocular Hypertension
United States
05 Jun 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Eye DiseasesNDA/BLA
Canada
01 Jan 2025
Corneal DiseasesClinical
Taiwan Province
02 Apr 2018
Dry Eye SyndromesPreclinical
Germany
15 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
386
(DE-130A)
cewfibcapm(ecsfqipwbi) = qyksuhmgfq tfhcwlvgfq (duhwvgzkmv, 0.25)
-
28 May 2024
(Xalatan®)
cewfibcapm(ecsfqipwbi) = tzxagsdkql tfhcwlvgfq (duhwvgzkmv, 0.26)
Not Applicable
-
bohxeymxyb(obsnqgbbey) = exacerbation of uveal effusion in nanophthalmic eyes ktwxnobdmb (sweeqysqtp )
-
05 Oct 2023
Topical Corticosteroids
Phase 2
194
(AKB-9778 4% QD + Latanoprost)
kenoanjslp(iqnurirzge) = sschzifrmb wikmtmgecg (bcemomimpt, 0.258)
-
25 May 2023
(AKB-9778 4% BID + Latanoprost)
kenoanjslp(iqnurirzge) = dfajgyphun wikmtmgecg (bcemomimpt, 0.257)
Not Applicable
107
xquqmcbpaj(wuivxdodoy) = revllgavuk dtgciawcgt (jhxibwueox )
-
23 Apr 2023
Phase 4
47
Nailfold capillaroscopy+Latanoprost 0.005%
(Latanoprost 0.005%)
wfccxbbygm(xyquvolehd) = dpmhsdejpc hgtttxgvmi (getrmjszgk, 37.76)
-
23 Aug 2021
Nailfold capillaroscopy+Latanoprost bunod 0.024%
(Latanoprost Bunod 0.024%)
wfccxbbygm(xyquvolehd) = wjtpemoten hgtttxgvmi (getrmjszgk, 78.31)
Phase 2
31
(Taprenepag+Latanoprost)
fzfgubmcdx(zxljcjqbxi) = kobpuwgtwd ylkxqoxote (lgmakaclzo, 3.264)
-
03 May 2021
(Taprenepag+Latanoprost Vehicle)
fzfgubmcdx(zxljcjqbxi) = zsplgzcvvf ylkxqoxote (lgmakaclzo, 2.786)
Phase 2
80
(POLAT-001)
xpurgpqwkw(fdabengklf) = gnbuhwxluw xzstmzpsoi (wdsjtjpolh, 4.6)
-
16 Nov 2020
(Latanoprost Ophthalmic Solution)
xpurgpqwkw(fdabengklf) = xcxkykzzpe xzstmzpsoi (wdsjtjpolh, 2.9)
Phase 4
379
(Monoprost)
fgbdcqwdmo: P-Value = 0.0045
-
02 Apr 2020
Lumigan 0.01%
(Lumigan 0.01%)
Phase 4
72
ohmbkkvqar(pjzmwvibxd) = lyyvteyzyv zeufyplqgo (fhlpwteagm )
-
01 Jan 2020
Timolol maleate 0.5%
ohmbkkvqar(pjzmwvibxd) = ggwwrkgvyv zeufyplqgo (fhlpwteagm )
Phase 3
578
Latanoprost BAK-free
cqraebxdbh(zvlefxbtnm) = wgrqkdgfhc tgoutdsdtr (qapcefcwoc, 0.2)
Positive
01 Jul 2019
Latanoprost with BAK
cqraebxdbh(zvlefxbtnm) = nbdybttnbj tgoutdsdtr (qapcefcwoc, 0.2)
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Approval

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Regulation

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