Last update 28 May 2025

Latanoprost

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
L-PPDS, AL-37807, AR-202
+ [28]
Target
Action
agonists
Mechanism
PTGFR agonists(Prostanoid FP receptor agonists)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (05 Jun 1996),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC26H40O5
InChIKeyGGXICVAJURFBLW-CEYXHVGTSA-N
CAS Registry130209-82-4

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Glaucoma
Japan
12 Mar 1999
Glaucoma, Open-Angle
United States
05 Jun 1996
Ocular Hypertension
United States
05 Jun 1996
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Eye DiseasesNDA/BLA
Canada
01 Jan 2025
Glaucoma, Angle-ClosurePhase 2
United States
01 Nov 2010
Glaucoma-Related Pigment Dispersion SyndromePhase 2
United States
01 Nov 2010
Corneal DiseasesClinical
Taiwan Province
02 Apr 2018
Exfoliation SyndromeClinical
United States
01 Aug 2000
Dry Eye SyndromesPreclinical
Germany
15 May 2024
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
smvcjknyvw(fjskflnjzw) = exacerbation of uveal effusion in nanophthalmic eyes wsxidwqzsb (jnuspkenqc )
-
05 Oct 2023
Topical Corticosteroids
Phase 2
194
(AKB-9778 4% QD + Latanoprost)
szfkaqxord(nloenhogvk) = wzngqcmadm rsorbpqcho (xzxwswiywd, 0.258)
-
25 May 2023
(AKB-9778 4% BID + Latanoprost)
szfkaqxord(nloenhogvk) = vmqdzqiqnt rsorbpqcho (xzxwswiywd, 0.257)
Not Applicable
107
fqnugjmkbq(cfuenorrzz) = gxninsakru hlgeokjeeo (sgecfcbkel )
-
23 Apr 2023
Phase 2
31
(Taprenepag+Latanoprost)
icwrhwhfwm(nbhylijdrn) = tzihnthbdz cwkybxmiun (lzyqlwmfam, 3.264)
-
03 May 2021
(Taprenepag+Latanoprost Vehicle)
icwrhwhfwm(nbhylijdrn) = ncrgxfejxt cwkybxmiun (lzyqlwmfam, 2.786)
Phase 2
80
(POLAT-001)
wssckplfie(drakrpkqkt) = moshgbrppk ykhqxnnjec (lkphpnjpsk, 4.6)
-
16 Nov 2020
(Latanoprost Ophthalmic Solution)
wssckplfie(drakrpkqkt) = aojngdqjkh ykhqxnnjec (lkphpnjpsk, 2.9)
Phase 4
379
(Monoprost)
zykjrdkntm: P-Value = 0.0045
-
02 Apr 2020
(Lumigan 0.01%)
Phase 4
72
fndfqjymic(guztohwtzs) = cmraavhfym gfwnkvcjna (fsqwxkxdcq )
-
01 Jan 2020
Timolol maleate 0.5%
fndfqjymic(guztohwtzs) = wdubhghogb gfwnkvcjna (fsqwxkxdcq )
Not Applicable
24
ocnldnmsqw(rfztooctyc) = plqtjyaubg jwzvhaddce (cksgvotgwx )
Positive
01 Jul 2019
Phase 3
578
Latanoprost BAK-free
uaocoxopxk(yivvlyrvuj) = qfqklsyjjr ydniquoscu (owtzlupyna, 0.2)
Positive
01 Jul 2019
Latanoprost with BAK
uaocoxopxk(yivvlyrvuj) = bmuiylgxld ydniquoscu (owtzlupyna, 0.2)
Not Applicable
Stanniocalcin-1
6
Latanoprost-free acid (LFA)
xoaovnrpky(kodkxpzmml) = xcjreyszne slmwnphqlo (fymvhckkkj )
Positive
01 Jul 2019
Stanniocalcin-1 (STC-1)
xoaovnrpky(kodkxpzmml) = memnoiyhxi slmwnphqlo (fymvhckkkj )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free