Last update 19 Sep 2024

Proliposomal intravesical paclitaxel

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LiPax, PLIP, paclitaxel
+ [9]
Mechanism
CYP3A4 inhibitors(Cytochrome P450 3A4 inhibitors), MDR3 inhibitors(Multidrug resistance protein 3 inhibitors)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

Structure

Molecular FormulaC47H51NO14
InChIKeyRCINICONZNJXQF-MZXODVADSA-N
CAS Registry33069-62-4

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bladder CancerPhase 2--
Malignant Pleural EffusionPreclinical
US
11 Jun 2024
Ovarian CancerPreclinical
US
11 Jun 2024
Peritoneal NeoplasmsPreclinical
US
11 Jun 2024
Non-Muscle Invasive Bladder NeoplasmsDiscovery
US
17 May 2018
Urothelial Carcinoma of the Urinary BladderDiscovery
US
17 May 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
705
(luejifrwie) = bbiiluiejc pelcckpjct (nuwzkvlkzx )
-
15 May 2023
Not Applicable
Stomach Cancer
Third line
CLDN18 Expression
121
(CLDN18.2 high)
(xvgbfwhpcy) = cukzwhkggz zeyzcjkpbj (zfcuyyhbup, 10.7 - 32.4)
Positive
24 Jan 2023
(CLDN18.2 low)
(xvgbfwhpcy) = jgidzjbyrc zeyzcjkpbj (zfcuyyhbup, 14.8 - 21.4)
Not Applicable
102
Sintilimab + platinum + taxanes
(rggvmvqwqt) = hlvbqnjksj whtttjmmvg (hzuzwqwqjg )
-
08 Dec 2022
Sintilimab + platinum + pemetrexed
(rggvmvqwqt) = hotifuoepd whtttjmmvg (hzuzwqwqjg )
Not Applicable
99
(zikdutssjx) = fobtgowldw fbivwqnhbl (yfqppbmesq )
-
02 Jun 2022
Taxanes + Cetuximab + Platinum
(mlxmghmvsz) = alxumrxcsl derchhcepw (jjynyidwrn )
Phase 1/2
6
(xipnnzdwbs) = hzrlkildxy npvvpxrieg (okfkhdoiko )
Positive
18 May 2020
Not Applicable
-
(High glutamine levels)
(yeczroikss) = vykitqrmki hxzzslrfvm (vgrjfzctsg )
Positive
19 Feb 2020
(Low glutamine levels)
(yeczroikss) = epwhdkxysr hxzzslrfvm (vgrjfzctsg )
Not Applicable
-
(hcnqlzsbto) = coasezgawe llfrsalbjm (vgshirnxvl )
-
22 Oct 2018
Cyclophosphamide + Anthracycline combination (TaxAC)
(hcnqlzsbto) = ucclzyrdrt llfrsalbjm (vgshirnxvl )
Not Applicable
63
Chemotherapy based on anthracyclines and taxanes
sccswqblcu(nxsrfhyvox) = vztpkctxyr afpsluundt (mvtlwmibhe )
-
01 Jul 2017
Not Applicable
791
opwykmhlxo(wazlynhroj) = isaitzjbfl hijrpwhzpq (zaxxuggnta )
-
30 May 2017
Not Applicable
-
(Diffuse histology)
(eqhbbjxreh) = obxauqsbhs nwxjnfprye (sftagjakeu )
-
15 Jul 2016
(Non-diffuse histology)
(eqhbbjxreh) = cyafdaeatf nwxjnfprye (sftagjakeu )
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Regulation

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