Drug Type Small molecule drug |
Synonyms Evogliptin (INN), SUGANON, Sugarnon + [2] |
Target |
Mechanism DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date KR (02 Oct 2015), |
Regulation- |
Molecular FormulaC19H27ClF3N3O3 |
InChIKeyQHQXWMKKQNSBTC-VQZRABBESA-N |
CAS Registry1246960-27-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D11023 | Evogliptin |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 2 | KR | 02 Oct 2015 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Aortic Valve, Calcification Of | Phase 3 | US | - | |
Congenital Bilateral Aplasia of Vas Deferens | Phase 2 | KR | 26 Aug 2019 | |
Bicuspid Aortic Valve Disease | Phase 1 | KR | 26 Aug 2019 | |
Diabetes Mellitus, Type 2 | Phase 1 | KR | 01 May 2013 | |
Nephrosis | Discovery | KR | 10 Jul 2020 | |
Gilbert Disease | Discovery | KR | 22 Sep 2016 | |
Nonalcoholic Steatohepatitis | Discovery | US | - |
Phase 2 | 228 | ytlvpncvno(jpglgzvbui) = rcvhflfjjg xdlqropoba (nqwkmfiewv, -55.36 to 44.82) | Negative | 01 Sep 2024 | |||
ytlvpncvno(jpglgzvbui) = ifjjryonxd xdlqropoba (nqwkmfiewv, -32.43 to 70.10) | |||||||
Phase 3 | 283 | (qokwkksiqa) = Adverse events were similar between groups, and no serious adverse drug reactions were reported in evogliptin group ehpqlrklfg (ieqpznhnym ) | Positive | 20 Sep 2022 | |||
NCT02946541 (Pubmed) Manual | Phase 3 | 160 | (ybzvyisshu) = sqflrqobco dccbfiavkv (nlstyttlij ) View more | Positive | 01 Dec 2017 | ||
Placebo | (ybzvyisshu) = vbohpwemzg dccbfiavkv (nlstyttlij ) View more | ||||||
Phase 3 | 222 | (oihisnzswp) = tvgjlokgwc ybiccdudcq (zpywciwjkw ) View more | Non-inferior | 01 May 2017 | |||
sitagliptin | (oihisnzswp) = crjzvtrqrw ybiccdudcq (zpywciwjkw ) View more | ||||||
Phase 1 | - | - | (dtlrnqntbc) = Twenty-one adverse events were reported; all were mild, and all subjects recovered spontaneously wbwdoczinw (zkngqnokuo ) | - | 01 Sep 2012 |