Last update 21 Nov 2024

Evogliptin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Evogliptin (INN), SUGANON, Sugarnon
+ [2]
Target
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
KR (02 Oct 2015),
Regulation-
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Structure

Molecular FormulaC19H27ClF3N3O3
InChIKeyQHQXWMKKQNSBTC-VQZRABBESA-N
CAS Registry1246960-27-9
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
D11023Evogliptin

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
KR
02 Oct 2015
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Aortic Valve, Calcification OfPhase 3
US
-
Congenital Bilateral Aplasia of Vas DeferensPhase 2
KR
26 Aug 2019
Bicuspid Aortic Valve DiseasePhase 1
KR
26 Aug 2019
Diabetes Mellitus, Type 2Phase 1
KR
01 May 2013
NephrosisDiscovery
KR
10 Jul 2020
Gilbert DiseaseDiscovery
KR
22 Sep 2016
Nonalcoholic SteatohepatitisDiscovery
US
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
228
ytlvpncvno(jpglgzvbui) = rcvhflfjjg xdlqropoba (nqwkmfiewv, -55.36 to 44.82)
Negative
01 Sep 2024
ytlvpncvno(jpglgzvbui) = ifjjryonxd xdlqropoba (nqwkmfiewv, -32.43 to 70.10)
Phase 3
283
(qokwkksiqa) = Adverse events were similar between groups, and no serious adverse drug reactions were reported in evogliptin group ehpqlrklfg (ieqpznhnym )
Positive
20 Sep 2022
Phase 3
160
(ybzvyisshu) = sqflrqobco dccbfiavkv (nlstyttlij )
Positive
01 Dec 2017
Placebo
(ybzvyisshu) = vbohpwemzg dccbfiavkv (nlstyttlij )
Phase 3
222
(oihisnzswp) = tvgjlokgwc ybiccdudcq (zpywciwjkw )
Non-inferior
01 May 2017
sitagliptin
(oihisnzswp) = crjzvtrqrw ybiccdudcq (zpywciwjkw )
Phase 1
-
-
(dtlrnqntbc) = Twenty-one adverse events were reported; all were mild, and all subjects recovered spontaneously wbwdoczinw (zkngqnokuo )
-
01 Sep 2012
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Regulation

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