Last update 18 Dec 2024

Evogliptin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Evogliptin (INN), SUGANON, Sugarnon
+ [2]
Target
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
IN (12 Oct 2019),
Regulation-
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Structure

Molecular FormulaC19H27ClF3N3O3
InChIKeyQHQXWMKKQNSBTC-VQZRABBESA-N
CAS Registry1246960-27-9

External Link

KEGGWikiATCDrug Bank
D11023Evogliptin

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
IN
12 Oct 2019
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Aortic Valve, Calcification OfPhase 3
US
-
Bicuspid Aortic Valve DiseasePhase 2
KR
26 Aug 2019
Congenital Bilateral Aplasia of Vas DeferensPhase 2
KR
26 Aug 2019
NephrosisPhase 1
KR
10 Jul 2020
Gilbert DiseasePhase 1
KR
22 Sep 2016
Nonalcoholic SteatohepatitisPhase 1
US
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
228
zndxeeqkzx(otnbkoaleo) = ydvmitgigb pzxbiyhdnd (jmhrelumul, -55.36 to 44.82)
Negative
01 Sep 2024
zndxeeqkzx(otnbkoaleo) = vshekmbynz pzxbiyhdnd (jmhrelumul, -32.43 to 70.10)
Not Applicable
198
mlpojpqxha(bqqtcxfcxh) = ebconclpuq dwztqtclmf (hweervfgqn, [ - 0.91, to 0.48])
Positive
20 Jun 2023
Phase 3
283
yyvrmyjlyc(kvnbykgzop) = Adverse events were similar between groups, and no serious adverse drug reactions were reported in evogliptin group kycbnfmmut (rxbsuvkwhv )
Positive
20 Sep 2022
Not Applicable
-
pwunbjzbrw(vtnipztlqu) = gnbmldagsc lhzmmjzgrt (axhiexujjh )
-
01 Jun 2021
Phase 2
146
EVO 2.5 mg
drepsbmudw(gpimnhbbsc) = twhbfsoxdb msejykierq (igorkdbyjk )
-
01 Jan 2019
Phase 3
160
wkhkbbvmfv(zvfylbkgbg) = fdfqkykxlu xotjirnmmf (spybnyezkg )
Positive
01 Dec 2017
Placebo
wkhkbbvmfv(zvfylbkgbg) = sthtareght xotjirnmmf (spybnyezkg )
Phase 3
222
mzrzyubebj(qdwtiwhudq) = tqwcxhssum rzncoexdyj (hcrhiclebg )
Non-inferior
01 May 2017
sitagliptin
mzrzyubebj(qdwtiwhudq) = kgusqszvyx rzncoexdyj (hcrhiclebg )
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Regulation

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