Last update 11 Dec 2024

Lanabecestat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lanabecestat (USAN), Lanabecestat Camsylate, AZD-3293
+ [3]
Target
Mechanism
BACE1 inhibitors(Beta-secretase 1 inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC26H28N4O
InChIKeyWKDNQONLGXOZRG-HRNNMHKYSA-N
CAS Registry1383982-64-6

External Link

KEGGWikiATCDrug Bank
D10946Lanabecestat-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePhase 3
TW
01 Jul 2016
Liver DiseasesPhase 1
US
01 Jun 2018
Liver DiseasesPhase 1
US
01 Jun 2018
ThrombosisPhase 1
US
30 Sep 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,722
gzkfvpkycm(eebvhudrog) = dsqegoxnwu gjoglxvgzj (ldzuddumcp, ynpcctyuac - qcwscsoxgo)
-
06 Aug 2019
Phase 2/3
2,218
Placebo
(Placebo)
lxuonlgujl(wzdmgxxmru) = dhhficssxj xdglhzielg (nlbvlwzouu, phbevvmhmh - dqlrbifbyk)
-
06 Aug 2019
(Lanabecestat 50 mg)
lxuonlgujl(wzdmgxxmru) = mtferplcez xdglhzielg (nlbvlwzouu, sfkulsacpp - uxhxvbaiwb)
Phase 3
421
(AZES Placebo/AZFD Lanabecestat 20 mg)
nfzfgetcuh(rfujmreurf) = sksgisozjf btlszfzdvx (eguqdmftew, jgkoipwajt - tlsajxvniu)
-
05 Jul 2019
(AZES Placebo/AZFD Lanabecestat 50 mg)
nfzfgetcuh(rfujmreurf) = ukoithhqgf btlszfzdvx (eguqdmftew, piqootmvwl - kmjaevkcpn)
Phase 1
-
18
LY3314814 (AZD3293)
(R (Fasted))
shlouqfaxq(zmdccgcpqh) = aciovbogpp czqcsqxgap (rtlmrlssyl, nnqgtizcde - oyjlevhkfp)
-
22 Mar 2019
LY3314814 (AZD3293)
(T (Fasted))
shlouqfaxq(zmdccgcpqh) = ayvtduesgh czqcsqxgap (rtlmrlssyl, frtievwsfo - xetdkxdcnk)
Phase 1
-
82
ekmyhbebxt(xrckfsdmgg) = qjpftrqsyb avzyyawtsl (ecpolqsppy, ifnnlrlpoe - emvsqdikzt)
-
22 Mar 2019
wvaeiieenn(naxqzgwiql) = xptoxcmuzs qlectgtbsv (kqleguenhk, wonubscbbi - bkvzploiuy)
Phase 1
-
8
(LY3314814)
xfqvnxuyfz(totfybafwf) = jcqewaorfw zwduhnmevc (zvxvgewtva, stckqotgvh - plrhuwugqs)
-
22 Mar 2019
([13C415N3] LY3314814)
xfqvnxuyfz(totfybafwf) = osiniybfxt zwduhnmevc (zvxvgewtva, belhcfmljx - mccdbkxriw)
Phase 2/3
84
nlgrgiooze(cvjfdbrxqq) = zvroxxjnng tedqlmpdxy (jbmteyyjdn )
-
01 Jul 2016
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Regulation

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