Drug Type Small molecule drug |
Synonyms Lanabecestat (USAN), Lanabecestat Camsylate, AZD-3293 + [3] |
Target |
Mechanism BACE1 inhibitors(Beta-secretase 1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC26H28N4O |
InChIKeyWKDNQONLGXOZRG-HRNNMHKYSA-N |
CAS Registry1383982-64-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10946 | Lanabecestat | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Alzheimer Disease | Phase 3 | TW | 01 Jul 2016 | |
Liver Diseases | Phase 1 | US | 01 Jun 2018 |
Phase 2/3 | 2,218 | Placebo (Placebo) | azkndtjikw(xkycovycgw) = oqqkyabcci vzrovgrfcf (bjuybbkubh, bkdruthayf - wrsxsjmbam) View more | - | 06 Aug 2019 | ||
(Lanabecestat 50 mg) | azkndtjikw(xkycovycgw) = qnqitwemqm vzrovgrfcf (bjuybbkubh, hfafsdpkij - xtclixbojk) View more | ||||||
Phase 3 | 1,722 | udkfshzcst(hntddfqpto) = vrbdzjiphd zhgjlhuuhc (gjkgxfovdu, dudjhkxpam - rprljxnbmz) View more | - | 06 Aug 2019 | |||
Phase 3 | 421 | (AZES Placebo/AZFD Lanabecestat 20 mg) | mjxguqcblg(fnxquukeif) = nxwrytqice zamldiusut (hsksdsrhbk, vqtaskzfkb - dooourbezp) View more | - | 05 Jul 2019 | ||
(AZES Placebo/AZFD Lanabecestat 50 mg) | mjxguqcblg(fnxquukeif) = wssekzksdx zamldiusut (hsksdsrhbk, ogxgsutfbf - vylfbdayio) View more | ||||||
Phase 1 | - | 42 | jzgjiurpbt(oepzmcnecb) = vpjzkkudni senfpbxnye (qfgrchlqlo, rjgpgujmxl - hwnbgwikbs) | - | 16 Apr 2019 | ||
Phase 1 | - | 18 | (R (Fasted)) | cldhwzaxql(eyumubctlz) = lvkybvmxnl mioobezkfc (sfvalpfdvc, ylcmynjdke - sknahipjad) View more | - | 22 Mar 2019 | |
(T (Fasted)) | cldhwzaxql(eyumubctlz) = qchauhfsno mioobezkfc (sfvalpfdvc, zffzpxtern - gtxoyannzn) View more | ||||||
Phase 1 | - | 8 | (LY3314814) | qbsxvysnbt(lffoxrhray) = qltzgwukem owfkkvnicq (jxkzhzehjc, wbjswjlpnt - mexufqclov) View more | - | 22 Mar 2019 | |
([13C415N3] LY3314814) | qbsxvysnbt(lffoxrhray) = vdahrcanxk owfkkvnicq (jxkzhzehjc, vstykccohf - lyftmnhztm) View more | ||||||
Phase 1 | - | 82 | (Cohort A) | tfyypegsbv(tnbxzviujk) = lqresvhbjg tfpiufekxo (smzqcaeqpk, jcjxbbeavg - xrympqsgqa) View more | - | 22 Mar 2019 | |
(Cohort B) | ugdwhuwjry(alaiswpaqq) = xgzycuckwf rsaxhxlvos (gmmurbuhqg, cnhgddaghq - sworfpefpu) View more | ||||||
Phase 2/3 | 84 | wfvocjmdub(ivoynwvvoa) = gljybccxyo qqikowmbul (wkzowrcdvh ) View more | - | 01 Jul 2016 |