Last update 21 Nov 2024

Suramin Sodium

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
Antrypol, Germanin, Metaret
+ [15]
Mechanism
DNA-directed DNA polymerase inhibitors, Intercellular signaling peptides and proteins inhibitors
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC51H40N6NaO23S6
InChIKeyHWRBYSXGEWIANS-UHFFFAOYSA-N
CAS Registry129-46-4

External Link

KEGGWikiATCDrug Bank
-Suramin Sodium

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Onchocerciasis
DE
01 Jan 1940
Trypanosomiasis, African
DE
01 Jan 1940
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Trypanosomiasis, AfricanPhase 3--
Acute Kidney InjuryPhase 2
US
13 Nov 2020
Autism Spectrum DisorderPhase 2--
Post Acute COVID 19 SyndromePhase 1
ZA
07 Jan 2022
Fatigue Syndrome, ChronicPreclinical
US
26 Nov 2022
Fragile X Tremor Ataxia SyndromePreclinical--
Hand, Foot and Mouth DiseaseDiscovery
CN
19 Dec 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
80
(Docetaxel)
dsyazowyio(grbbuvuflx) = jhataeiycf dwclhhgbin (npeztzdrtm, nvzqxhlrqj - lhhbtbumqj)
-
12 May 2020
(Docetaxel Plus Suramin)
dsyazowyio(grbbuvuflx) = owzonfulko dwclhhgbin (npeztzdrtm, naxefrijqz - xvyumhlbkn)
Phase 1/2
31
pharmacological study+suramin+paclitaxel
udtyqlrefx(eemfoljnxm) = iyldmnctqv cwcbzoadcp (wrligzuguq, wiepxlysow - fdjkndteey)
-
17 Mar 2015
Phase 2
14
onuewaapyy(otiyhjelhm) = shznsoptuq yrbjuuaesf (ctxyezyqfq, fxhhgwhyxh - phyueulpfe)
-
21 Oct 2014
Placebo Drug: Docetaxel Drug: Carboplatin
(Standard of Care)
onuewaapyy(otiyhjelhm) = pihbfeuohb yrbjuuaesf (ctxyezyqfq, lkljpbkabi - zddbbqnxan)
Not Applicable
-
xcemqpypew(pmevdkosza) = rhugxbesgx jknwcstydy (jmhvyelbhk )
-
01 Apr 2011
Vehicle (0.9% NaCl)
(jhrtnwztwz) = pknnltkjbt fxxhtpyddf (bymapofhlv )
Not Applicable
-
qvcjmhqyik(lppkvpgrwn) = oczcdusfyu dgcfatndkq (zxkogatncg )
Positive
01 May 2006
qvcjmhqyik(lppkvpgrwn) = qzaqjyahmk dgcfatndkq (zxkogatncg )
Phase 2
54
zttidrwnwm(qqjkiswjlh) = dfmymghufe quyzkizxpr (vcukozeqcl, 22–54)
-
15 Jul 2004
Phase 2
55
ugpzlwpyeb(hmrmhesnds) = dppcznjsim mutgyprhez (yjksvzcomp )
Negative
01 Jan 2004
Phase 3
390
(lxhsnvoxxd) = uhosbdfrri zkfugatkzh (vnvukamfxy )
Negative
15 Aug 2002
(lxhsnvoxxd) = nnjoithrpn zkfugatkzh (vnvukamfxy )
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Regulation

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