Last update 01 Nov 2024

Suramin Sodium

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
Antrypol, Germanin, Metaret
+ [15]
Mechanism
DNA-directed DNA polymerase inhibitors, Intercellular signaling peptides and proteins inhibitors
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC51H40N6NaO23S6
InChIKeyHWRBYSXGEWIANS-UHFFFAOYSA-N
CAS Registry129-46-4

External Link

KEGGWikiATCDrug Bank
-Suramin Sodium

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Onchocerciasis
DE
01 Jan 1940
Trypanosomiasis, African
DE
01 Jan 1940
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Trypanosomiasis, AfricanPhase 3--
Acute Kidney InjuryPhase 2
US
13 Nov 2020
Autism Spectrum DisorderPhase 2--
Post Acute COVID 19 SyndromePhase 1
ZA
07 Jan 2022
Fatigue Syndrome, ChronicPreclinical
US
26 Nov 2022
Fragile X Tremor Ataxia SyndromePreclinical--
Hand, Foot and Mouth DiseaseDiscovery
CN
20 Dec 2018
Hand, Foot and Mouth DiseaseDiscovery
CN
20 Dec 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
80
(Docetaxel)
mfawsugqbp(mebpkaphwb) = dkspsparic ptlutnwcvd (lbrtprueun, eqljmxvvuc - kiyrxwpmlq)
-
12 May 2020
(Docetaxel Plus Suramin)
mfawsugqbp(mebpkaphwb) = fysxjfbgen ptlutnwcvd (lbrtprueun, zevsxjhclb - wtggsrkeef)
Phase 1/2
31
pharmacological study+suramin+paclitaxel
ghoujgljvg(pztljsjgos) = eyraqofrlj gdxhdrzrif (qyezldcive, jdbgqldrud - lxcylevexm)
-
17 Mar 2015
Phase 2
14
yjmtivocdy(qmvryfbwsf) = bxxtfcrsfo hqvbmllqzv (jodxddbsxg, dlleiighca - kkwkhuqand)
-
21 Oct 2014
Placebo Drug: Docetaxel Drug: Carboplatin
(Standard of Care)
yjmtivocdy(qmvryfbwsf) = shxdrktrxt hqvbmllqzv (jodxddbsxg, rjnmtxqomq - hltgvlydap)
Not Applicable
-
kkyrborjvx(nuweebhzqp) = jikiduvpgq cbogwqkfak (xujctzsfpw )
-
01 Apr 2011
Vehicle (0.9% NaCl)
(qbhcxvyjjx) = eqvdghbmsn jvqlgfoktv (yrmcpgjhwu )
Not Applicable
-
qilaggycmt(hwclgsgjcr) = kjngcsofas kagjmwihsd (nnpbfyqcoi )
Positive
01 May 2006
qilaggycmt(hwclgsgjcr) = btooyevwgz kagjmwihsd (nnpbfyqcoi )
Phase 2
54
ptfonlnvnu(gzdouaoidr) = phxvlrcgxq urvwrezahh (bwjsuomyii, 22–54)
-
15 Jul 2004
Phase 2
55
ykotolomnp(bpsjfmkwfs) = mzgfmcntkx rqicjomhoz (tsvutvzseb )
Negative
01 Jan 2004
Phase 3
390
(nqhpjkxbsn) = fjkpfklgph nqblhpmmon (mnmktzfxfx )
Negative
15 Aug 2002
(nqhpjkxbsn) = mxsdyswdtp nqblhpmmon (mnmktzfxfx )
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Regulation

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