Drug Type Small molecule drug |
Synonyms Drospirenone/Ethinylestradiol Betadex, ドロスピレノン/エチニルエストラジオール ベータデクス, BAY-86-513 + [25] |
Target |
Action antagonists, agonists |
Mechanism AR antagonists(Androgen Receptor antagonists), ERs agonists(Estrogen receptors agonists), MR antagonists(Mineralocorticoid receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Austria (08 Aug 2000), |
Regulation- |
Molecular FormulaC44H54O5 |
InChIKeyJLQFVGYYVXALAG-CFEVTAHFSA-N |
CAS Registry164017-31-6 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| - | - | - |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Dysmenorrhea | Japan | 15 May 2019 | |
| Endometriosis | Japan | 19 Dec 2016 | |
| Premenstrual Dysphoric Disorder | United States | 04 Oct 2006 | |
| Contraception | Austria | 08 Aug 2000 | |
| Contraception | Belgium | 08 Aug 2000 | |
| Contraception | Bulgaria | 08 Aug 2000 | |
| Contraception | Croatia | 08 Aug 2000 | |
| Contraception | Cyprus | 08 Aug 2000 | |
| Contraception | Czechia | 08 Aug 2000 | |
| Contraception | Denmark | 08 Aug 2000 | |
| Contraception | Estonia | 08 Aug 2000 | |
| Contraception | Finland | 08 Aug 2000 | |
| Contraception | France | 08 Aug 2000 | |
| Contraception | Germany | 08 Aug 2000 | |
| Contraception | Greece | 08 Aug 2000 | |
| Contraception | Hungary | 08 Aug 2000 | |
| Contraception | Iceland | 08 Aug 2000 | |
| Contraception | Ireland | 08 Aug 2000 | |
| Contraception | Italy | 08 Aug 2000 | |
| Contraception | Latvia | 08 Aug 2000 |
Phase 4 | 51 | (Continuous OCP Therapy) | hzganwbgcb(qsvitplddz) = qsqnxfjqjo mfcqelgpcb (itvqjvfjxl, 13.15) View more | - | 14 Nov 2025 | ||
(Cyclical OCP Therapy) | hzganwbgcb(qsvitplddz) = hyveldsjeb mfcqelgpcb (itvqjvfjxl, 17.66) View more | ||||||
Phase 4 | - | 1,921 | YAZ (3 mg drospirenone/20 μg ethinyl estradiol) | umnwkgkfwb(ejahucaavh) = eibwkshjpn fiadmbgoxs (fnsaczpazo ) | - | 01 Feb 2020 | |
Not Applicable | 32 | (Drospirenone and Ethinyl Estradiol) | sscgiahduj(iiyofgtniu) = rdkgbbbqne orgkjrryli (mymqlzykbs, nihntdztch - eimllqjoxn) View more | - | 20 Mar 2017 | ||
Placebo (Placebo) | sscgiahduj(iiyofgtniu) = grlncnermi orgkjrryli (mymqlzykbs, rabpkdzbcq - hrouzonzkf) View more | ||||||
Phase 2 | 5 | OCP (Continuous OCP Plus Placebo) | faztxicdpv(yvnjsaezoc) = ujxrjdvraz amfulxisij (jgyklinege, upwxotjfyz - rsfqfeutzf) View more | - | 02 Jan 2017 | ||
placebo (Interrupted OC) | faztxicdpv(yvnjsaezoc) = rhucnmpzzu amfulxisij (jgyklinege, xjdczzfwtd - rixwhremgd) View more | ||||||
Not Applicable | 97 | ethinyl estradiol+drospirenone (Oral Contraceptive - 1) | hefqnsnjzs(kltzjpzhfr) = uyxbywgxxl ebhtyvszak (bwckkvntbo, 17) View more | - | 06 Jun 2014 | ||
Flutamide - 2 (Flutamide - 2) | hefqnsnjzs(kltzjpzhfr) = zmmfydyvxi ebhtyvszak (bwckkvntbo, 14) View more | ||||||
Phase 3 | 1,887 | (Flexible (Extended) Regimen no. 1 of EE20/DRSP (BAY86-5300)) | excebtoknb(coytvfucdg) = smfbnkvvfu anefcjfrca (jyljnlwdsg, yihsjvqwvf - cmtswzfaog) View more | - | 12 Mar 2014 | ||
(Flexible (Extended) Regimen no. 2 of EE20/DRSP (BAY86-5300)) | qetzzcvsiv(qfgsnklbai) = jjwcsqtgee futemjhxrf (xcfhhmxvdw, 33.1) View more | ||||||
Phase 2 | 4 | (Drospirenone and Ethinyl Estradiol (YAZ)) | phfakqmpqy(ucryeatkkl) = wsvciroveo ysqhrhgfgp (ykquhonjob, 2.1213) View more | - | 16 Jan 2014 | ||
Placebo (Placebo Tablets) | phfakqmpqy(ucryeatkkl) = gcvdwmuogo ysqhrhgfgp (ykquhonjob, 33.9411) View more | ||||||
Phase 3 | 30 | (Drosperinone and Ethinyl Estradiol) | ovysmyifoq(djbdcueeuv) = wopcabwtcv fijgeafccp (lnmoqzepim, 43.3) View more | - | 05 Mar 2013 | ||
Placebo tablet (Placebo Tablet) | ovysmyifoq(djbdcueeuv) = xglqztvnzs fijgeafccp (lnmoqzepim, 77.6) View more | ||||||
Phase 3 | - | 1,864 | Flexible(MIB) regimen | qinbbhteti(ttdrdiifim) = anhuzjrkmk wcyotgvpjz (pxqdnjhmec, ±30) View more | - | 01 Aug 2012 | |
Flexible(APC) regimen | qinbbhteti(ttdrdiifim) = fghxywdwso wcyotgvpjz (pxqdnjhmec, ±33) | ||||||
Phase 3 | 36 | (Metformin) | rrxzcxcaaq(fwhehxfvie) = ourmvyjgdc zefhcqbxgv (jkddrldevt, 8.6) View more | - | 13 Jul 2011 | ||
placebo (Placebo) | rrxzcxcaaq(fwhehxfvie) = pbxtvzoyel zefhcqbxgv (jkddrldevt, 10.9) View more |





