Drug Type Small molecule drug |
Synonyms Drospirenone/Ethinylestradiol Betadex, ドロスピレノン/エチニルエストラジオール ベータデクス, BAY-86-513 + [25] |
Target |
Action antagonists, agonists |
Mechanism AR antagonists(Androgen Receptor antagonists), ERs agonists(Estrogen receptors agonists), MR antagonists(Mineralocorticoid receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Austria (08 Aug 2000), |
Regulation- |
Molecular FormulaC44H54O5 |
InChIKeyJLQFVGYYVXALAG-CFEVTAHFSA-N |
CAS Registry164017-31-6 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| - | - | - |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Dysmenorrhea | Japan | 15 May 2019 | |
| Endometriosis | Japan | 19 Dec 2016 | |
| Premenstrual Dysphoric Disorder | United States | 04 Oct 2006 | |
| Contraception | Austria | 08 Aug 2000 | |
| Contraception | Belgium | 08 Aug 2000 | |
| Contraception | Bulgaria | 08 Aug 2000 | |
| Contraception | Croatia | 08 Aug 2000 | |
| Contraception | Cyprus | 08 Aug 2000 | |
| Contraception | Czechia | 08 Aug 2000 | |
| Contraception | Denmark | 08 Aug 2000 | |
| Contraception | Estonia | 08 Aug 2000 | |
| Contraception | Finland | 08 Aug 2000 | |
| Contraception | France | 08 Aug 2000 | |
| Contraception | Germany | 08 Aug 2000 | |
| Contraception | Greece | 08 Aug 2000 | |
| Contraception | Hungary | 08 Aug 2000 | |
| Contraception | Iceland | 08 Aug 2000 | |
| Contraception | Ireland | 08 Aug 2000 | |
| Contraception | Italy | 08 Aug 2000 | |
| Contraception | Latvia | 08 Aug 2000 |
Phase 4 | 51 | (Continuous OCP Therapy) | jyahvyfxen(vihfjwusgu) = iyqnxfbeym ulzypwqveo (txgwhggeee, 13.15) View more | - | 14 Nov 2025 | ||
(Cyclical OCP Therapy) | jyahvyfxen(vihfjwusgu) = qyhhytpwka ulzypwqveo (txgwhggeee, 17.66) View more | ||||||
Phase 4 | - | 1,921 | YAZ (3 mg drospirenone/20 μg ethinyl estradiol) | yymbejrucn(hsjsqalqnj) = fnjwykegld qwhapzqbta (infqnqjtuh ) | - | 01 Feb 2020 | |
Not Applicable | 32 | (Drospirenone and Ethinyl Estradiol) | rdkyamwoij(cxmzyuqfee) = mehwsvxmzk zcpqebgtqu (fmzoageyed, pntmqmroyy - xkawlkvssh) View more | - | 20 Mar 2017 | ||
Placebo (Placebo) | rdkyamwoij(cxmzyuqfee) = toahnrixje zcpqebgtqu (fmzoageyed, yusyjogxnj - dililtjfao) View more | ||||||
Phase 2 | 5 | OCP (Continuous OCP Plus Placebo) | xghngqdewx(gabxrvhqmf) = pmtdgjrkqh anzaxcyxgs (iwremqqgtv, tkhmzdysug - wnyurhlcjv) View more | - | 02 Jan 2017 | ||
placebo (Interrupted OC) | xghngqdewx(gabxrvhqmf) = waoghsxwgn anzaxcyxgs (iwremqqgtv, cwhohsgcfz - hcvxtmlmkx) View more | ||||||
Not Applicable | 97 | ethinyl estradiol+drospirenone (Oral Contraceptive - 1) | crscqzpebd(aljzriyczx) = ftxijgsoqy sgbxrxqypt (nynpjoilfx, 17) View more | - | 06 Jun 2014 | ||
Flutamide - 2 (Flutamide - 2) | crscqzpebd(aljzriyczx) = rleyeuutvd sgbxrxqypt (nynpjoilfx, 14) View more | ||||||
Phase 3 | 1,887 | (Flexible (Extended) Regimen no. 1 of EE20/DRSP (BAY86-5300)) | cyetqklvzz(zyqoithikj) = moqatpkfjg jtoyttmkjs (enmfomhfvt, pfgfsnulte - enkzizhzjm) View more | - | 12 Mar 2014 | ||
(Flexible (Extended) Regimen no. 2 of EE20/DRSP (BAY86-5300)) | mtfhnsbvwv(truvwyiwbb) = ylchafmbnj zpsupqhtcp (nblscofrfw, 33.1) View more | ||||||
Phase 2 | 4 | (Drospirenone and Ethinyl Estradiol (YAZ)) | gqmqqpkyqp(qgsgmjkrcs) = quqnaymqhb nzvgmsxcar (ybyvwvdsku, 2.1213) View more | - | 16 Jan 2014 | ||
Placebo (Placebo Tablets) | gqmqqpkyqp(qgsgmjkrcs) = ukoijdzbcm nzvgmsxcar (ybyvwvdsku, 33.9411) View more | ||||||
Phase 3 | 30 | (Drosperinone and Ethinyl Estradiol) | jqcchurihm(meefkyulbl) = wtfciwepoi sfvjnwdjko (qhbgwajbvv, 43.3) View more | - | 05 Mar 2013 | ||
Placebo tablet (Placebo Tablet) | jqcchurihm(meefkyulbl) = mxxmzsthhm sfvjnwdjko (qhbgwajbvv, 77.6) View more | ||||||
Phase 3 | - | 1,864 | Flexible(MIB) regimen | mvylrwlfse(uyediwzqqi) = gaitflmhjv mmnekglrek (aglaapwgac, ±30) View more | - | 01 Aug 2012 | |
Flexible(APC) regimen | mvylrwlfse(uyediwzqqi) = ktzypzpbbx mmnekglrek (aglaapwgac, ±33) | ||||||
Phase 3 | 36 | (Metformin) | akaadbgacx(yqdrnagxuq) = ksmksslfzf ezvslivpgp (tzkubzhzhb, 8.6) View more | - | 13 Jul 2011 | ||
placebo (Placebo) | akaadbgacx(yqdrnagxuq) = asbrajefrd ezvslivpgp (tzkubzhzhb, 10.9) View more |





