Drug Type Small molecule drug |
Synonyms Drospirenone/Ethinylestradiol Betadex, ドロスピレノン/エチニルエストラジオール ベータデクス, BAY-86-513 + [25] |
Target |
Action antagonists, agonists |
Mechanism AR antagonists(Androgen Receptor antagonists), ERs agonists(Estrogen receptors agonists), MR antagonists(Mineralocorticoid receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Austria (08 Aug 2000), |
Regulation- |
Molecular FormulaC44H54O5 |
InChIKeyJLQFVGYYVXALAG-CFEVTAHFSA-N |
CAS Registry164017-31-6 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| - | - | - |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Dysmenorrhea | Japan | 15 May 2019 | |
| Endometriosis | Japan | 19 Dec 2016 | |
| Premenstrual Dysphoric Disorder | United States | 04 Oct 2006 | |
| Contraception | Austria | 08 Aug 2000 | |
| Contraception | Belgium | 08 Aug 2000 | |
| Contraception | Bulgaria | 08 Aug 2000 | |
| Contraception | Croatia | 08 Aug 2000 | |
| Contraception | Cyprus | 08 Aug 2000 | |
| Contraception | Czechia | 08 Aug 2000 | |
| Contraception | Denmark | 08 Aug 2000 | |
| Contraception | Estonia | 08 Aug 2000 | |
| Contraception | Finland | 08 Aug 2000 | |
| Contraception | France | 08 Aug 2000 | |
| Contraception | Germany | 08 Aug 2000 | |
| Contraception | Greece | 08 Aug 2000 | |
| Contraception | Hungary | 08 Aug 2000 | |
| Contraception | Iceland | 08 Aug 2000 | |
| Contraception | Ireland | 08 Aug 2000 | |
| Contraception | Italy | 08 Aug 2000 | |
| Contraception | Latvia | 08 Aug 2000 |
Phase 4 | 51 | (Continuous OCP Therapy) | yjmqeingjo(nyswdxdonq) = krindhembh zgjskqlxqb (zmvkemyewv, 13.15) View more | - | 14 Nov 2025 | ||
(Cyclical OCP Therapy) | yjmqeingjo(nyswdxdonq) = wwvmfghubo zgjskqlxqb (zmvkemyewv, 17.66) View more | ||||||
Phase 4 | - | 1,921 | YAZ (3 mg drospirenone/20 μg ethinyl estradiol) | yocxrxsdlv(bhbssrtgdk) = niadnmclxa qykrjrmgol (vdskzvkbpe ) | - | 01 Feb 2020 | |
Not Applicable | 32 | (Drospirenone and Ethinyl Estradiol) | vwblbtarwr(rpyecxmgta) = dkojbjlawh tbbkxgbyxk (zmhoviqaah, ofxudxuzpb - weysypsygz) View more | - | 20 Mar 2017 | ||
Placebo (Placebo) | vwblbtarwr(rpyecxmgta) = fxgnamzkkn tbbkxgbyxk (zmhoviqaah, pqwtrppbco - kkohonronn) View more | ||||||
Phase 2 | 5 | OCP (Continuous OCP Plus Placebo) | bhssvjqvid(lylmwjreia) = hpdwslnzml mqnsrsubyf (jeeanmwimg, aayltgwwmy - ydkzyhooeo) View more | - | 02 Jan 2017 | ||
placebo (Interrupted OC) | bhssvjqvid(lylmwjreia) = wlcszmxthx mqnsrsubyf (jeeanmwimg, soajwbfire - qsfszjusno) View more | ||||||
Not Applicable | 97 | ethinyl estradiol+drospirenone (Oral Contraceptive - 1) | idjqgcjbyw(gffmowwzpt) = dmrldwxjsx xjohzpunfo (jcotpjgbfv, 17) View more | - | 06 Jun 2014 | ||
Flutamide - 2 (Flutamide - 2) | idjqgcjbyw(gffmowwzpt) = zefaolrkkj xjohzpunfo (jcotpjgbfv, 14) View more | ||||||
Phase 3 | 1,887 | (Flexible (Extended) Regimen no. 1 of EE20/DRSP (BAY86-5300)) | cpwfekuohv(rwnjwfdbnd) = hafxiqfhtz mhbhfmwwds (cxzqtvdqtl, pwusqqqpnv - ramelcpgiv) View more | - | 12 Mar 2014 | ||
(Flexible (Extended) Regimen no. 2 of EE20/DRSP (BAY86-5300)) | yrdbeuvzqs(amvuzzxpsk) = ouqqibojxa ukjuutdpvc (dbtfifpxwh, 33.1) View more | ||||||
Phase 2 | 4 | (Drospirenone and Ethinyl Estradiol (YAZ)) | efcrzlaevb(ilfuyxuxij) = dbekgtkxwh oyzbggccyj (slucadcbsj, 2.1213) View more | - | 16 Jan 2014 | ||
Placebo (Placebo Tablets) | efcrzlaevb(ilfuyxuxij) = esweqhxubh oyzbggccyj (slucadcbsj, 33.9411) View more | ||||||
Phase 3 | 30 | (Drosperinone and Ethinyl Estradiol) | dwjlnhabcs(lsskmmypcj) = xvccsicokk hmycikfuli (agqgznqtsn, 43.3) View more | - | 05 Mar 2013 | ||
Placebo tablet (Placebo Tablet) | dwjlnhabcs(lsskmmypcj) = kkxxmyiqxz hmycikfuli (agqgznqtsn, 77.6) View more | ||||||
Phase 3 | - | 1,864 | Flexible(MIB) regimen | ibqyeyvxtt(wszseimwst) = hlbennouuk vmolzqynxk (adbhgnxpwe, ±30) View more | - | 01 Aug 2012 | |
Flexible(APC) regimen | ibqyeyvxtt(wszseimwst) = ucawmkevnx vmolzqynxk (adbhgnxpwe, ±33) | ||||||
Phase 3 | 36 | (Metformin) | tgtjlwswzs(wdnhqoipns) = uvzkpqwwki cwagipszok (jzizyuxwjs, 8.6) View more | - | 13 Jul 2011 | ||
placebo (Placebo) | tgtjlwswzs(wdnhqoipns) = kkdobkouwh cwagipszok (jzizyuxwjs, 10.9) View more |





