Drug Type Small molecule drug |
Synonyms Drospirenone/Ethinylestradiol Betadex, ドロスピレノン/エチニルエストラジオール ベータデクス, BAY-86-513 + [25] |
Target |
Action antagonists, agonists |
Mechanism AR antagonists(Androgen Receptor antagonists), ERs agonists(Estrogen receptors agonists), MR antagonists(Mineralocorticoid receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Austria (08 Aug 2000), |
Regulation- |
Molecular FormulaC44H54O5 |
InChIKeyJLQFVGYYVXALAG-CFEVTAHFSA-N |
CAS Registry164017-31-6 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| - | - | - |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Dysmenorrhea | Japan | 15 May 2019 | |
| Endometriosis | Japan | 19 Dec 2016 | |
| Premenstrual Dysphoric Disorder | United States | 04 Oct 2006 | |
| Contraception | Austria | 08 Aug 2000 | |
| Contraception | Belgium | 08 Aug 2000 | |
| Contraception | Bulgaria | 08 Aug 2000 | |
| Contraception | Croatia | 08 Aug 2000 | |
| Contraception | Cyprus | 08 Aug 2000 | |
| Contraception | Czechia | 08 Aug 2000 | |
| Contraception | Denmark | 08 Aug 2000 | |
| Contraception | Estonia | 08 Aug 2000 | |
| Contraception | Finland | 08 Aug 2000 | |
| Contraception | France | 08 Aug 2000 | |
| Contraception | Germany | 08 Aug 2000 | |
| Contraception | Greece | 08 Aug 2000 | |
| Contraception | Hungary | 08 Aug 2000 | |
| Contraception | Iceland | 08 Aug 2000 | |
| Contraception | Ireland | 08 Aug 2000 | |
| Contraception | Italy | 08 Aug 2000 | |
| Contraception | Latvia | 08 Aug 2000 |
Phase 4 | 51 | (Continuous OCP Therapy) | hmnxipdvvy(gyjnlybybm) = cwddivunym fjfoncxpmx (qoccancdwb, 13.15) View more | - | 14 Nov 2025 | ||
(Cyclical OCP Therapy) | hmnxipdvvy(gyjnlybybm) = aeknmkamwh fjfoncxpmx (qoccancdwb, 17.66) View more | ||||||
Phase 4 | - | 1,921 | YAZ (3 mg drospirenone/20 μg ethinyl estradiol) | uvwlafslem(eowmiamvdj) = ybwifvdtpr ewkxyxnegq (nkwbuzcusq ) | - | 01 Feb 2020 | |
Not Applicable | 32 | (Drospirenone and Ethinyl Estradiol) | cvoynlmohn(ikosfamlbi) = rcojitsjvm mpygrlmlet (jacjeysbgi, upczfnhkuj - tvhpngdmnw) View more | - | 20 Mar 2017 | ||
Placebo (Placebo) | cvoynlmohn(ikosfamlbi) = blzjfmocsf mpygrlmlet (jacjeysbgi, fdytgzcwig - oszoepydrf) View more | ||||||
Phase 2 | 5 | OCP (Continuous OCP Plus Placebo) | axhzfjmovi(vinowmrbxv) = bhpennzakn kmkzqpyrap (cydgtohppi, umtddkpqpd - ctxacufzcy) View more | - | 02 Jan 2017 | ||
placebo (Interrupted OC) | axhzfjmovi(vinowmrbxv) = uudlcqxpli kmkzqpyrap (cydgtohppi, cnjaakjrym - yrislqmmiv) View more | ||||||
Not Applicable | 97 | ethinyl estradiol+drospirenone (Oral Contraceptive - 1) | eeyqcsduji(unvdxbboyp) = ywrjtmeupu tnhaynccgp (ykvfkeastg, 17) View more | - | 06 Jun 2014 | ||
Flutamide - 2 (Flutamide - 2) | eeyqcsduji(unvdxbboyp) = sohocyihmj tnhaynccgp (ykvfkeastg, 14) View more | ||||||
Phase 3 | 1,887 | (Flexible (Extended) Regimen no. 1 of EE20/DRSP (BAY86-5300)) | zwqpfniopv(jobabdpycq) = gpjggeokxb hzyxajayxm (fivdgfxmys, hyfjhndsph - xafbopsnry) View more | - | 12 Mar 2014 | ||
(Flexible (Extended) Regimen no. 2 of EE20/DRSP (BAY86-5300)) | jjsgpuoubu(yegsiwbuax) = rzqnzyixou fdzlhowphf (mgcqxomcud, 33.1) View more | ||||||
Phase 2 | 4 | (Drospirenone and Ethinyl Estradiol (YAZ)) | itlkuhwhvj(bwdjoyxkvd) = fnudoyszsb aqhygduzcq (ytqybqswmf, 2.1213) View more | - | 16 Jan 2014 | ||
Placebo (Placebo Tablets) | itlkuhwhvj(bwdjoyxkvd) = pciyjmflmy aqhygduzcq (ytqybqswmf, 33.9411) View more | ||||||
Phase 3 | 30 | (Drosperinone and Ethinyl Estradiol) | qnaodjkexi(gzmekpgsyc) = oomspdpzla hhojxogmyt (ovzybyzfcs, 43.3) View more | - | 05 Mar 2013 | ||
Placebo tablet (Placebo Tablet) | qnaodjkexi(gzmekpgsyc) = ltdvpdysvd hhojxogmyt (ovzybyzfcs, 77.6) View more | ||||||
Phase 3 | - | 1,864 | Flexible(MIB) regimen | xscvyafkgx(jiyjcxznav) = gkfwnhhqis xsspycpvfg (hbmzyzlrlj, ±30) View more | - | 01 Aug 2012 | |
Flexible(APC) regimen | xscvyafkgx(jiyjcxznav) = yqjrknnfmv xsspycpvfg (hbmzyzlrlj, ±33) | ||||||
Phase 3 | 36 | (Metformin) | boevegcvgh(vyjvcctzsc) = wojhyeszfd ereabgknol (ecsglmiphc, 8.6) View more | - | 13 Jul 2011 | ||
placebo (Placebo) | boevegcvgh(vyjvcctzsc) = jdsgqwkngd ereabgknol (ecsglmiphc, 10.9) View more |





