Drug Type Small molecule drug |
Synonyms Drospirenone/Ethinylestradiol Betadex, ドロスピレノン/エチニルエストラジオール ベータデクス, BAY-86-513 + [21] |
Target |
Action antagonists, agonists |
Mechanism AR antagonists(Androgen Receptor antagonists), ERs agonists(Estrogen receptors agonists), MR antagonists(Mineralocorticoid receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date Austria (08 Aug 2000), |
Regulation- |
Molecular FormulaC44H54O5 |
InChIKeyJLQFVGYYVXALAG-CFEVTAHFSA-N |
CAS Registry164017-31-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Dysmenorrhea | Japan | 15 May 2019 | |
Endometriosis | Japan | 19 Dec 2016 | |
Premenstrual Dysphoric Disorder | United States | 04 Oct 2006 | |
Contraception | Austria | 08 Aug 2000 | |
Contraception | Belgium | 08 Aug 2000 | |
Contraception | Bulgaria | 08 Aug 2000 | |
Contraception | Croatia | 08 Aug 2000 | |
Contraception | Cyprus | 08 Aug 2000 | |
Contraception | Czechia | 08 Aug 2000 | |
Contraception | Denmark | 08 Aug 2000 | |
Contraception | Estonia | 08 Aug 2000 | |
Contraception | Finland | 08 Aug 2000 | |
Contraception | France | 08 Aug 2000 | |
Contraception | Germany | 08 Aug 2000 | |
Contraception | Greece | 08 Aug 2000 | |
Contraception | Hungary | 08 Aug 2000 | |
Contraception | Iceland | 08 Aug 2000 | |
Contraception | Ireland | 08 Aug 2000 | |
Contraception | Italy | 08 Aug 2000 | |
Contraception | Latvia | 08 Aug 2000 |
Phase 3 | 1,887 | (Flexible (Extended) Regimen no. 1 of EE20/DRSP (BAY86-5300)) | zkyorprngg(etfuunnpwq) = bjvfifrtvh vtixchtezq (vznorjisry, yfhafbusfi - tavtxcqnld) View more | - | 12 Mar 2014 | ||
(Flexible (Extended) Regimen no. 2 of EE20/DRSP (BAY86-5300)) | yswddurrlb(wxomlfeeit) = ccfquhorxd mdgppwncut (tzqpuinstz, 33.1) View more | ||||||
Phase 3 | 36 | (Metformin) | nbyyuycfyx(lfykwfvysc) = ipxyjzhdaw lhqcppnpsi (pivecmljox, 8.6) View more | - | 13 Jul 2011 | ||
placebo (Placebo) | nbyyuycfyx(lfykwfvysc) = dhkuzukpms lhqcppnpsi (pivecmljox, 10.9) View more | ||||||
Phase 1 | 172 | folic acid placebo+EE 0.03 mg/DRSP 3 mg (Yasmin) (EE 0.03 mg/DRSP 3 mg/Metafolin + Folic Acid Placebo) | uhizzkzxau(nrqlcbpyxr) = ccxkeyljbu ekyoyhlesl (hrsbngklux, htzmvhrcbo - sajvqyueev) View more | - | 13 May 2011 | ||
(EE 0.03 mg/DRSP 3 mg (Yasmin) + Folic Acid) | uhizzkzxau(nrqlcbpyxr) = tfmdytdztx ekyoyhlesl (hrsbngklux, mfjipbzqws - svmkpfimcm) View more | ||||||
Phase 2/3 | 249 | (DRSP 1 mg/EE 20 μg) | aurjnlttmd(lrcxnwuaek) = nraxnbexph crenkulnyx (sbhpcawmey, 1.52) View more | - | 04 Oct 2010 | ||
(DRSP 2 mg/EE 20 μg) | aurjnlttmd(lrcxnwuaek) = ntepyvxvgn crenkulnyx (sbhpcawmey, 1.51) View more | ||||||
Phase 3 | 1,166 | (Flexible (Extended) Treatment of EE20/DRSP (YAZ, BAY86-5300)) | agdvebhgtz(sxrhmoehvp) = iuodirncnh vvkxxrubpo (moichylnmr, 29) View more | - | 03 Mar 2010 | ||
(Fixed Extended Treatment of EE20/DRSP (YAZ, BAY86-5300)) | agdvebhgtz(sxrhmoehvp) = wmsbqwlnvp vvkxxrubpo (moichylnmr, 51) View more |