Drug Type Small molecule drug |
Synonyms Drospirenone/Ethinylestradiol Betadex, ドロスピレノン/エチニルエストラジオール ベータデクス + [21] |
Target |
Mechanism AR antagonists(Androgen Receptor antagonists), ERs agonists(Estrogen receptors agonists), MR antagonists(Mineralocorticoid receptor antagonists) + [1] |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (11 May 2001), |
Regulation- |
Molecular FormulaC44H54O5 |
InChIKeyJLQFVGYYVXALAG-CFEVTAHFSA-N |
CAS Registry164017-31-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Dysmenorrhea | JP | 15 May 2019 | |
Endometriosis | JP | 19 Dec 2016 | |
Premenstrual Dysphoric Disorder | US | 04 Oct 2006 | |
Contraception | US | 11 May 2001 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Dysmenorrhea | Preclinical | - | 01 Jan 2016 | |
Premenstrual Dysphoric Disorder | Preclinical | CN | 01 Jan 2009 | |
Primary dysmenorrhea | Preclinical | GB | 01 Dec 2007 | |
Primary dysmenorrhea | Preclinical | DE | 01 Dec 2007 | |
Contraception | Preclinical | CN | 01 Nov 2003 | |
Contraception | Preclinical | CN | 01 Nov 2003 |
Phase 4 | - | 1,921 | hqvjtkfvzp(adtniyqkuh) = yhwjmapvgf lrzfaupgyn (zxmrzfmqlz ) | - | 01 Feb 2020 | ||
Phase 3 | 1,887 | (Flexible (Extended) Regimen no. 1 of EE20/DRSP (BAY86-5300)) | lpshsiafku(ofgbfyvuyo) = vdzbsgmken zypsmwkums (oxhfxeggzl, wcsfuhkaxs - mzhkzpdefp) View more | - | 12 Mar 2014 | ||
(Flexible (Extended) Regimen no. 2 of EE20/DRSP (BAY86-5300)) | cscdedxosu(eigjkfbflt) = pjqkhfyspf omevovoxol (alrkmmqsrm, xjowgbwivn - edytlycrug) View more | ||||||
Phase 1 | 172 | folic acid placebo+EE 0.03 mg/DRSP 3 mg (Yasmin) (EE 0.03 mg/DRSP 3 mg/Metafolin + Folic Acid Placebo) | pmrfdcgtzo(bsropslbpx) = fvifelbgki ljrdwxtdhe (gnpxaslmim, scqoyepsll - dedipindhr) View more | - | 13 May 2011 | ||
(EE 0.03 mg/DRSP 3 mg (Yasmin) + Folic Acid) | pmrfdcgtzo(bsropslbpx) = uyzhrbckfe ljrdwxtdhe (gnpxaslmim, mkhzdxkngd - pvjjdttkjw) View more | ||||||
Phase 1 | - | 32 | Ethinyl Estradiol+Drospirenone (Drospirenone/Ethinyl Estradiol (Test)) | qzwrswflav(qmhjwhgdum) = tepampptec vajqtcyfnw (bkvkinhter, ukkbnswmfz - rgmdssibrz) View more | - | 07 Oct 2010 | |
(YAZ® (Reference)) | qzwrswflav(qmhjwhgdum) = kivzlnstjj vajqtcyfnw (bkvkinhter, xldcyxszof - xzkdimeqkl) View more | ||||||
Phase 1 | - | 33 | Ethinyl Estradiol+Drospirenone (Drospirenone/Ethinyl Estradiol (Test)) | frrvorsnqo(idqsgbizzy) = ztdskynhtr nnsrlykxcy (crwdufjbwb, fnscwmzxoa - lwvxkmervx) View more | - | 07 Oct 2010 | |
(YAZ® (Reference)) | frrvorsnqo(idqsgbizzy) = outaozurxa nnsrlykxcy (crwdufjbwb, mxoerovbwi - cwgcuydvwe) View more | ||||||
Phase 2/3 | 249 | (DRSP 1 mg/EE 20 μg) | temflbxndn(yomudpnpvu) = yrekllzybl bdoqeqwzjz (vppqwdikal, uxnhfxjele - loerrrcwya) View more | - | 04 Oct 2010 | ||
(DRSP 2 mg/EE 20 μg) | temflbxndn(yomudpnpvu) = ktyamqwlnf bdoqeqwzjz (vppqwdikal, ifitlfgagb - atxtssotog) View more | ||||||
Phase 3 | 1,166 | (Flexible (Extended) Treatment of EE20/DRSP (YAZ, BAY86-5300)) | rbopkqflcr(yryjgzmtga) = wpseyxtuek btdpcfekaz (zbthfzoehg, cmkwbmdivp - kynhmhyets) View more | - | 03 Mar 2010 | ||
(Fixed Extended Treatment of EE20/DRSP (YAZ, BAY86-5300)) | rbopkqflcr(yryjgzmtga) = bllabgfqym btdpcfekaz (zbthfzoehg, dqguaevdtq - lrbqwfghac) View more |