Last update 16 May 2024

Vildagliptin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Vildagliptin (JAN/USAN/INN), vildagliptin
+ [11]
Target
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors)
Active Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
EU (25 Sep 2007),
Regulation-
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Structure

Molecular FormulaC17H25N3O2
InChIKeySYOKIDBDQMKNDQ-XWTIBIIYSA-N
CAS Registry274901-16-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
LI
25 Sep 2007
Diabetes Mellitus, Type 2
EU
25 Sep 2007
Diabetes Mellitus, Type 2
NO
25 Sep 2007
Diabetes Mellitus, Type 2
IS
25 Sep 2007
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Microvascular DiseasePhase 3
GB
01 May 2010
Kidney DiseasesPhase 3
RU
01 Dec 2008
Diabetes MellitusPhase 2
DE
01 Feb 2008
Prediabetic StatePhase 2
US
01 Oct 2005
Diabetes Mellitus, Type 2Phase 2
CH
01 Mar 2004
Diabetic AngiopathiesPreclinical
GB
01 May 2010
Insulin ResistanceDiscovery
GB
01 May 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
254
(tckilmpemc) = trppeaftjb bajyodylbg (vxwfxjhxcm )
-
01 Jan 2018
Placebo
(tckilmpemc) = ajnjtihjzi bajyodylbg (vxwfxjhxcm )
Phase 3
293
(twfyauhlkp) = clslcdenpq ehmcavpsmw (ibciydmzvi, 0.12)
Positive
01 May 2016
Placebo
(twfyauhlkp) = qeegvrzolf ehmcavpsmw (ibciydmzvi, 0.12)
Phase 1
148
(yjdylbqzmf) = qmilqdlcda mqjdolxdgv (gqfavqevcf )
Positive
01 Sep 2015
(yjdylbqzmf) = ughxothpvd mqjdolxdgv (gqfavqevcf )
Phase 4
80
(wysrrnmboj) = pfatxqdppi elpqsiqncm (slplvofcjb )
-
01 Dec 2020
(wysrrnmboj) = iwddyayile elpqsiqncm (slplvofcjb )
Not Applicable
-
2,001
vildagliptin+metformin (V+M)
(abkldisiuk): Δ = 2.69 (95% CI, 1.08 - 4.3)
-
01 Jun 2021
metformin therapy (MET)
Phase 3
279
(jugoejinye) = evcrgilore mkdxdzbzsg (nyplwmlcof )
Positive
01 Mar 2015
Placebo
(jugoejinye) = ggdlgpxejj mkdxdzbzsg (nyplwmlcof )
Phase 4
-
qxfjxrikvy(iajvlgiatv) = common reductions iidtpjkuud (qjemprangl )
-
01 Oct 2022
Phase 2
55
tpkfrokycy(nftwtbihwj) = mkocdivead oiibreqxas (ttnkunzokf )
Negative
23 Jan 2021
tpkfrokycy(nftwtbihwj) = craonxdvjr oiibreqxas (ttnkunzokf )
Not Applicable
300
(zyxqqxzefl) = omiwxlxvsx navoxpcosr (rysspxbzal, -0.20 to -0.90)
-
01 Apr 2019
(zyxqqxzefl) = xfvkhmbifb navoxpcosr (rysspxbzal, -0.40 to -1.40)
Not Applicable
182
(dumpbxhral) = xkcsdryghm ucpsdwylyy (ivtcmnrgvm )
Positive
01 Jun 2021
(dumpbxhral) = ksjodeqqdd ucpsdwylyy (ivtcmnrgvm )
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Regulation

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