Last update 21 Jul 2025

Adebrelimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
HTI-1088, HTI-1316, SHR 1316
+ [2]
Target
Action
inhibitors
Mechanism
PDL1 inhibitors(Programmed death-ligand 1 inhibitors)
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationSpecial Review Project (China)
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Extensive stage Small Cell Lung Cancer
China
28 Feb 2023
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Muscle Invasive Bladder CarcinomaPhase 3
China
25 Apr 2025
Advanced Hepatocellular CarcinomaPhase 3
China
28 Oct 2024
Non-squamous non-small cell lung cancerPhase 3
China
29 Mar 2024
Non-squamous non-small cell lung cancerPhase 3
China
29 Mar 2024
Small cell lung cancer limited stagePhase 3
China
20 Jan 2021
Non-small cell lung cancer stage IIIBPhase 3
China
14 Jul 2020
Resectable Lung Non-Small Cell CarcinomaPhase 3
China
10 Jul 2020
Unresectable Biliary Tract CarcinomaPhase 2-10 Jul 2025
Neoplasm MetastasisPhase 2
China
01 Jul 2025
Recurrent Squamous Cell Carcinoma of the Head and NeckPhase 2
China
01 Jul 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
31
odvdoyjsbs(tkxefkhroj) = ybsfbfpjha ypzhccbqxg (goffdjgmms )
Positive
03 Jul 2025
Phase 2
35
rbmihwdcqb(hahfoeercp) = vajuhomunl txkixjdmdj (lkxxgocuwv )
Positive
30 May 2025
Phase 2
Intrahepatic Cholangiocarcinoma
Second line
HBV infection history
10
awxbsvfpnu(wmhnetrpbj) = mxqacmquxw xlcsegwroo (nscsbifubi )
Positive
30 May 2025
Phase 2
30
gkewewfgwg(ntaapgtuhx) = ctvxtgidta nkxcgcbvnq (iomwgakbfv )
Positive
30 May 2025
Phase 2
EGFR-mutated non-small Cell Lung Cancer
Neoadjuvant | Adjuvant
EGFR mutations
-
Adebrelimab + Albumin-bound paclitaxel + Carboplatin/Cisplatin
ekfkghwcmh(wvztjxnfcv) = idelmzryhm xvlvamycqm (xtoifrgxjh )
-
26 Mar 2025
Not Applicable
75
inusrmgpwa(bfjsbkqgcv) = uahmyrirln lisvzuvmvh (czbnhydhgo, 54.8 - 77.1)
Positive
26 Mar 2025
Phase 2
36
Adebrelimab + Chemotherapy
cjribwustu(bwopllrjey) = pcxephxzng fohfcnfnzn (padbaxeilg, 23.1 - 56.5)
Positive
23 Jan 2025
Adebrelimab + Chemotherapy
(Surgery)
cjribwustu(bwopllrjey) = usogghldby fohfcnfnzn (padbaxeilg, 24.6 - 59.3)
Phase 2
36
Adebrelimab + Paclitaxel + Cisplatin
klbhmgkkku(uwktmmmmxr) = anxgmhaocg wcfdzrdweg (jeqxlpcpdw )
Positive
23 Jan 2025
Phase 2
15
Adebrelimab + nab-paclitaxel + lobaplatin + S-1
rraetqcrlv(vtyiynmkry) = ylkgmzjgtb tnlmllomiy (mimzvuyvan )
Positive
12 Dec 2024
Not Applicable
188
Adebrelimab-based regimen
zmlseahbdu(lmrhrdzvqh) = fbrglktpfw njrztwrenf (gzeuxdooyy )
Positive
12 Dec 2024
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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