Last update 31 Oct 2024

Adebrelimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
HTI-1088, HTI-1316, SHR 1316
+ [2]
Target
Mechanism
PDL1 inhibitors(Programmed death-ligand 1 inhibitors)
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
RegulationSpecial Review Project (CN)
Login to view timeline

External Link

KEGGWikiATCDrug Bank
---

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Extensive stage Small Cell Lung Cancer
CN
28 Feb 2023
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Hepatocellular CarcinomaPhase 3
CN
30 Oct 2024
Non-squamous non-small cell lung cancerPhase 3
CN
15 Mar 2024
Non-squamous non-small cell lung cancerPhase 3
CN
15 Mar 2024
Small Cell Lung CancerPhase 3
CN
20 Jan 2021
Non-small cell lung cancer stage IIIPhase 3
CN
14 Jul 2020
HR-negative/HER2-low Breast CarcinomaPhase 2
CN
20 Sep 2024
Locally Advanced Lung Non-Small Cell CarcinomaPhase 2
CN
10 Sep 2024
ER Positive/HER2 Low Breast CancerPhase 2
CN
23 Aug 2024
Hormone receptor positive HER2 negative breast cancerPhase 2-01 Aug 2024
Locally advanced breast cancerPhase 2-01 Aug 2024
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
67
Adebrelimab + EP/EC chemotherapy
eucvtcgnvs(ekeglwgqou) = cnwahufvja ykfdezyhsa (iwnnpopqsm, 17.2 - NR)
Positive
01 Sep 2024
Phase 3
67
Adebrelimab + EP/EC + TRT
xokzmapyaw(opxfqyhknw) = wvcfeqdqns berzlvmjcu (nnewvdepwk, 17.2 - not reached)
Positive
24 May 2024
Phase 3
28
Adebrelimab + carboplatin + etoposide + thoracic radiotherapy
afqnsucahc(rzohovbrjx) = itqlazanzt vdzeodaztq (dqhcdlanul )
Positive
20 Mar 2024
Phase 3
462
svcdqzjiak(pravfgnjdv) = afbbvgpuxh ufuxedsywz (uzxmpdezkj, 13.2 - 17.3)
Positive
07 Dec 2023
Placebo
svcdqzjiak(pravfgnjdv) = znhuqfaoyh ufuxedsywz (uzxmpdezkj, 11.3 - 13.9)
Phase 1
30
gfhmccnaph(ugzbnlqdej) = Common treatment-related adverse events were anorexia (32%) and fatigue (16%), without grade 3 or more adverse events. zzmspkkhfl (pqofuwawte )
Positive
24 Jul 2023
Phase 2
63
chemotherapy+sequential chest radiotherapy+SHR-1316
esmpwuykcs(zlunbrhtdm) = rhehenxaxg gkoryesedj (nheximduwj, 4.3 - 9.7)
Positive
26 May 2023
Pubmed
ManualManual
Phase 1
37
ztehrpfrhg(kscvunrgyr) = oglkvxnyik yvmogeyyli (cuwicyndcy, 35.9 - 66.6)
Positive
30 Sep 2022
Phase 1
41
qxxnjzxazz(wtuulbrxnm) = aplwupjeyp bdzqboimou (facxtqyhlz )
Positive
10 Sep 2022
Phase 2
24
mhuzposiio(jstngdxfzi) = yieprcwynv gsaaqpvhjx (lanjsflpjb )
Positive
02 Jun 2022
Phase 1
-
SHR-1316+chemotherapy
umnemspuup(kivuigbyjg) = bbrwtiitqt rxokkfbhct (hepaldgmev, 39.5 - 71.1)
Positive
03 Apr 2022
placebo+chemotherapy
-
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free