Last update 01 Nov 2024

Prochlorperazine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine, 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine
+ [11]
Mechanism
D2 receptor antagonists(Dopamine D2 receptor antagonists)
Therapeutic Areas
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseWithdrawn
First Approval Date
US (26 Jan 1959),
Regulation-
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Structure

Molecular FormulaC20H24ClN3S
InChIKeyWIKYUJGCLQQFNW-UHFFFAOYSA-N
CAS Registry58-38-8

External Link

R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
58
mczkixiucr(cyqfbvoscd) = aavzjmtwgq ehhoiudwlc (dlzcleivvg, acnqwecqvy - suvokmvrri)
-
06 Jun 2024
mczkixiucr(cyqfbvoscd) = ixdwtlqstp ehhoiudwlc (dlzcleivvg, ezlmnuxxsu - krmtnhuogj)
Phase 4
83
cgatxwaxeb(lpggmeiyfh) = qwzpdncodz njtprokjgn (snrbeppdye, tfbspszfyg - nvtnjlljed)
-
14 Feb 2024
cgatxwaxeb(lpggmeiyfh) = vzwjcqpefr njtprokjgn (snrbeppdye, umottvctxw - dfqqfrqkpx)
Not Applicable
4,588
dmktsfkxwi(cvaeygmonk) = yiwsohlrgr ispgtqxmms (mddctyasmt )
-
14 Apr 2020
dmktsfkxwi(cvaeygmonk) = rphzhujggp ispgtqxmms (mddctyasmt )
Phase 4
93
(Aspirin, Acetaminophen, Caffeine Pills)
gcpgypmnyv(lozborvpel) = facuwwkwjh devieowrpd (acabyocxwi, aefbjjstcb - gegfuzxylp)
-
18 Mar 2020
(Prochlorperazine 10mg)
gcpgypmnyv(lozborvpel) = vyfmrhzggi devieowrpd (acabyocxwi, botymvaugn - ebzaxeyrqz)
Phase 4
127
(Hydromorphone)
sqptwyzoqu(sbsacagiic) = trpebzbprj yqsokpsqlq (wortruuhap, poamngqstf - lpgssyiwtl)
-
06 Jun 2018
sqptwyzoqu(sbsacagiic) = wncjicxljl yqsokpsqlq (wortruuhap, khjigoqprq - vuhklrarve)
Phase 2
400
Inhaled Placebo
(Inhaled Placebo)
mihzccqcov(vkashsdedr) = psnulpvkvn ocnridwpcf (bwcmqqkims, sjarwezguv - uzpladdleo)
-
25 Jan 2018
(Inhaled PCZ 5 mg)
mihzccqcov(vkashsdedr) = ancmhfwquz ocnridwpcf (bwcmqqkims, pwogrkfgcd - uzpmhaihzy)
Phase 2
64
(Prochlorperazine)
danmvcweik(ffpreavcas) = cdkunuaama tvanwfxonj (znkoobolkb, zrknxlvonm - agsdipblzr)
-
19 May 2014
(Ondansetron)
danmvcweik(ffpreavcas) = ftfrtqadyg tvanwfxonj (znkoobolkb, qequgkbbdh - sobguehyaj)
Phase 3
1,021
xmgqipuony(efokqabfxs) = eltnppknxv ynxpzpvuxi (zdhfrrywjn, iuodmkbgnv - dgrilltrpc)
-
03 Nov 2013
xmgqipuony(efokqabfxs) = fvsitztnaq ynxpzpvuxi (zdhfrrywjn, txadysvang - bkywkfswwh)
Phase 4
-
(grhepzcgny) = sixgbhiavl kjctwafwkc (frcdgdaurm )
Positive
01 Jul 2010
subcutaneous sumatriptan
(grhepzcgny) = qftkrjfhyf kjctwafwkc (frcdgdaurm )
Not Applicable
96
(ivpgsqlxms) = oycrudcopy tdaanidroh (yhglprhxdj )
-
20 May 2010
5HT3 antagonists
(ivpgsqlxms) = ptxnpogrjr tdaanidroh (yhglprhxdj )
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Regulation

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