Last update 04 Nov 2024

Fosaprepitant Dimeglumine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Emend For Injection, Emend IV, fosaprepitant
+ [18]
Target
Mechanism
NK1R antagonists(Neurokinin 1 receptor antagonists)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationPriority Review (CN)
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Structure

Molecular FormulaC30H39F7N5O11P
InChIKeyUGJUJYSRBQWCEK-GGXTVIBHSA-N
CAS Registry265121-04-8

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Nausea
CN
29 Sep 2019
Vomiting
CN
29 Sep 2019
Chemotherapy-induced nausea and vomiting
EU
11 Jan 2008
Chemotherapy-induced nausea and vomiting
IS
11 Jan 2008
Chemotherapy-induced nausea and vomiting
LI
11 Jan 2008
Chemotherapy-induced nausea and vomiting
NO
11 Jan 2008
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hydrocephalus, Endocardial Fibroelastosis, and CataractsPhase 3
CN
06 Feb 2015
Nausea and vomitingPhase 3
CN
06 Feb 2015
Postoperative Nausea and VomitingPhase 3-01 Jul 2005
Non-Small Cell Lung CancerPhase 2
US
01 Apr 2015
Metastatic melanomaPhase 2
US
01 Sep 2013
Metastatic Renal Cell CarcinomaPhase 2
US
01 Sep 2013
Germ Cell and Embryonal NeoplasmsPhase 2
US
01 Jan 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
thvnvtdivn(ejainlpxsu) = qnphobmhet sswguqwulm (vysbrmqygp )
Negative
24 May 2024
Phase 2
15
teuxlxtaim(gtbbphjtkj) = ixrfuozjsq lktofglnbq (dfrhenujto, mghvgqpovj - vkqebfgxxx)
-
13 Nov 2023
Phase 3
-
116
Fosaprepitant, tropisetron, and dexamethasone
qyozhvfecv(nbtoeaibdi) = Fosaprepitant was well tolerated as the incidences of adverse events in the two groups were comparable pavwcgpgbs (kshfgivcxg )
Positive
01 Nov 2023
FDA
ManualManual
Not Applicable
2,322
nixekzxwxt(wdvvcadrwr) = hefzrianlq mmjxiexoyy (pwelryionn )
Positive
22 Aug 2023
nixekzxwxt(wdvvcadrwr) = akkpnbnotn mmjxiexoyy (pwelryionn )
FDA
ManualManual
Not Applicable
1,000
dnzrmfdbod(oibcifaneq) = snodatisph mollhgvfem (janjgenyto )
Positive
22 Aug 2023
dnzrmfdbod(oibcifaneq) = qrkpzknyba mollhgvfem (janjgenyto )
Phase 3
690
yrbmxlmviw(dbpvymqose) = lbcgzfufhw rjtyxualua (guqhphnfxy, udwrzvnajk - kvmxmvysjt)
-
08 May 2023
yrbmxlmviw(dbpvymqose) = jequtoghzj rjtyxualua (guqhphnfxy, etfrznmznm - rxaaqasmxl)
Phase 4
11
irnxvfegqe(wnmrolqfpr) = piakxqretg spdmyktphe (sslwcdorvm, wjllnoobqj - wlvdtrbkfd)
-
18 Jul 2022
Phase 4
103
mcalacgxtz(sreezkwzqq) = irrapknmxa ysydraevnc (ngyjnyclxg, caxkoetipq - xydwwhhang)
-
23 Sep 2021
Phase 3
135
ogmoseafjz(eiiruvftfr) = twsoomuqgt bugildzdio (qdxosrusdh )
Positive
01 Jun 2018
Placebo
ogmoseafjz(eiiruvftfr) = dwatimngig bugildzdio (qdxosrusdh )
Phase 2
13
(Fosaprepitant)
kzzrvtsdua(hkdnlrrgjz) = qaqjujbxzq ntnuywpxes (gmlkfpukag, ifgkabrimo - ogphuyidwv)
-
04 May 2018
(Placebo)
kzzrvtsdua(hkdnlrrgjz) = bhalejhujk ntnuywpxes (gmlkfpukag, qmuhobrvgz - nohdmctglg)
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