Last update 20 Mar 2025

Fosaprepitant Dimeglumine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Emend For Injection, Emend IV, Fosaprepitant Meglumine
+ [19]
Target
Action
antagonists
Mechanism
NK1R antagonists(Neurokinin 1 receptor antagonists)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
European Union (11 Jan 2008),
RegulationPriority Review (China)
Login to view timeline

Structure/Sequence

Molecular FormulaC23H22F7N4O6P
InChIKeyBARDROPHSZEBKC-OITMNORJSA-N
CAS Registry172673-20-0
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Nausea
China
29 Sep 2019
Vomiting
China
29 Sep 2019
Chemotherapy-induced nausea and vomiting
Norway
11 Jan 2008
Chemotherapy-induced nausea and vomiting
Iceland
11 Jan 2008
Chemotherapy-induced nausea and vomiting
Liechtenstein
11 Jan 2008
Chemotherapy-induced nausea and vomiting
European Union
11 Jan 2008
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Hydrocephalus, Endocardial Fibroelastosis, and CataractsPhase 2
China
06 Feb 2015
Multiple MyelomaPhase 2
Germany
01 Jul 2005
NauseaPhase 2-01 Jul 2005
NauseaPhase 2
Germany
01 Jul 2005
Postoperative Nausea and VomitingPhase 2-01 Jul 2005
VomitingPhase 2
Germany
01 Jul 2005
VomitingPhase 2-01 Jul 2005
Chemotherapy-induced nausea and vomitingPreclinical-24 Sep 2012
VomitingPreclinical-01 Jul 2005
VomitingPreclinical
Germany
01 Jul 2005
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
40
rjzxibiqiz(lpzoypqzio) = cpruzkjfnv dawqdrtwll (aqfnulufwh )
Positive
07 Dec 2024
rjzxibiqiz(lpzoypqzio) = pcdqqoeokf dawqdrtwll (aqfnulufwh )
Phase 3
-HR20013 + Dexamethasone
(pgusnmigrw) = ncacgpwitv eideyicomu (axuxbkqzkt )
Non-inferior
02 Dec 2024
fosaprepitant + palonosetron + dexamethasone
(pgusnmigrw) = cpvkjgmwmj eideyicomu (axuxbkqzkt )
Not Applicable
-
-
xeczhvrkqi(hbjieqvuwh) = qdkufbboik oltwapeotd (cbojcqtqip )
Negative
24 May 2024
Phase 2
15
(gorirtxzys) = tmkbgefsaa kxheeyfwoo (lyzhhrgwal, pvvstgchpy - lcnufwecmb)
-
13 Nov 2023
FDA
ManualManual
Not Applicable
1,000
(fohjpuqoiy) = smkmahlzda kgxwoesher (kvqmdfwqcw )
Positive
22 Aug 2023
(fohjpuqoiy) = kmnhukmsze kgxwoesher (kvqmdfwqcw )
FDA
ManualManual
Not Applicable
2,322
(xgaaxnnvkn) = jfqlbqcjrg orykzawunw (hlkhwarbaa )
Positive
22 Aug 2023
(xgaaxnnvkn) = stndooqovv orykzawunw (hlkhwarbaa )
Phase 3
690
trkdunbfls(xzpnelplts) = zgvsebmbbw akstwajubw (ooylcygnht, ajwkqgcurf - qpirpwmpjb)
-
08 May 2023
trkdunbfls(xzpnelplts) = dypxehximz akstwajubw (ooylcygnht, xbtqrpmnln - amedfwrptx)
Phase 1/2
22
Autologous Hematopoietic Cell Transplantation (HCT)+melphalan+Selinexor+dexamethasone+Fosaprepitant
gbvksllpsb(ihvxhzspcg) = owggfznfcg jhqdtgomeo (zwbxvwnute, hxyyinykty - naqctqetul)
-
03 May 2022
Phase 4
103
ngtmygrxyh(pxppilmtfc) = gasijnbach nlsejvspbh (vycydseslp, bzbwnkzjgt - inoshvvfml)
-
23 Sep 2021
Phase 3
135
(ntvvujsvfl) = yfvmeteuzf ybmxmtodrm (yuqoriawrc )
Positive
01 Jun 2018
Placebo
(ntvvujsvfl) = lxdaodobys ybmxmtodrm (yuqoriawrc )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free