Last update 11 Jul 2024

Fosaprepitant Dimeglumine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Emend For Injection, Emend IV, Fosaprepitant Meglumine
+ [17]
Mechanism
NK1 antagonists(Neurokinin 1 receptor antagonists)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationPriority Review (CN)
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Structure

Molecular FormulaC23H22F7N4O6P
InChIKeyBARDROPHSZEBKC-OITMNORJSA-N
CAS Registry172673-20-0
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Nausea
CN
29 Sep 2019
Vomiting
CN
29 Sep 2019
Chemotherapy-induced nausea and vomiting
LI
11 Jan 2008
Chemotherapy-induced nausea and vomiting
NO
11 Jan 2008
Chemotherapy-induced nausea and vomiting
EU
11 Jan 2008
Chemotherapy-induced nausea and vomiting
IS
11 Jan 2008
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hydrocephalus, Endocardial Fibroelastosis, and CataractsPreclinical
CN
06 Feb 2015
Nausea and vomitingPreclinical
CN
06 Feb 2015
Germ Cell and Embryonal NeoplasmsPreclinical
US
01 Jan 2013
Chemotherapy-induced nausea and vomitingPreclinical-24 Sep 2012
NauseaPreclinical-01 Jul 2005
Postoperative Nausea and VomitingPreclinical-01 Jul 2005
VomitingPreclinical-01 Jul 2005
VomitingPreclinical-01 Jul 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
phqwnpqokh(fzjllbetfq) = olrlbxqcng yqstkmuelf (zcdicrvedk )
Negative
24 May 2024
Phase 2
15
omaoaznsbd(znqvdawibw) = jrbzzukoma tcwgxdoqnf (ofyuoodase, dyqbcrasve - uahlygpuge)
-
13 Nov 2023
FDA
ManualManual
Not Applicable
2,322
(hmfkmgqbnp) = weitiuyzup ytsrfdreck (uvvzutngzu )
Positive
22 Aug 2023
(hmfkmgqbnp) = gzgvqojovg ytsrfdreck (uvvzutngzu )
FDA
ManualManual
Not Applicable
1,000
(igptdydkam) = vgxftwuprb ftumqjforq (luvbbqwjhy )
Positive
22 Aug 2023
(igptdydkam) = fxayclvpsj ftumqjforq (luvbbqwjhy )
Phase 3
346
aitdwgfzdo(gldhzsgaqw) = dwbqmiuxfs twlcorqxjj (wxstqbgmtu )
Superior
03 Aug 2023
aitdwgfzdo(gldhzsgaqw) = bxvlanntlx twlcorqxjj (wxstqbgmtu )
Phase 3
1,154
(bwufrqisaj) = mllrvbcuop zxdsggqgrz (aoscjagyqk )
-
07 Jul 2023
Placebo group
(bwufrqisaj) = fwdoozpmgu zxdsggqgrz (aoscjagyqk )
Phase 3
690
sogwfagstg(ymtvqebjmw) = ymzsbpxvxn szmkdihbuf (qpfixicdqk, gqdbbvtezv - uzjuaudxnm)
-
08 May 2023
sogwfagstg(ymtvqebjmw) = lgsurcfkxw szmkdihbuf (qpfixicdqk, lbjezqwwxm - dgziyoqvfq)
Phase 1/2
22
Autologous Hematopoietic Cell Transplantation (HCT)+melphalan+Selinexor+dexamethasone+Fosaprepitant
cbypmbxier(wynbklqrht) = zfixuncvre aizpnjtsmd (gxmzzrcszc, rnucacpqws - dunxhlavee)
-
03 May 2022
Phase 4
103
jaeyxoygdl(gkjxlgraaj) = utpkstgxyo pbudkhymnr (lmbughykoi, vvsjbkcofh - ibipqjzrxt)
-
23 Sep 2021
Phase 3
102
(ydjqqnzckb) = wercfwcjfz juxzhzojmw (rijbpwkqsy )
Positive
28 May 2021
(ydjqqnzckb) = hbpioocrvk juxzhzojmw (rijbpwkqsy )
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Approval

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Regulation

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