Last update 24 Mar 2025

Pegvisomant

Overview

Basic Info

Drug Type
Hormone
Synonyms
pegviosomant, Pegvisomant (genetical recombination) (JAN), Pegvisomant (USAN/INN)
+ [7]
Target
Action
antagonists
Mechanism
GHR antagonists(Growth hormone receptor antagonists)
Active Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
European Union (12 Nov 2002),
RegulationOrphan Drug (United States), Orphan Drug (South Korea), Orphan Drug (Japan)
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Structure/Sequence

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acromegaly
European Union
12 Nov 2002
Acromegaly
Iceland
12 Nov 2002
Acromegaly
Liechtenstein
12 Nov 2002
Acromegaly
Norway
12 Nov 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
United States
01 Nov 2009
Advanced Malignant Solid NeoplasmPhase 1
Canada
01 Nov 2009
Advanced Malignant Solid NeoplasmPhase 1
Finland
01 Nov 2009
Advanced Malignant Solid NeoplasmPhase 1
Germany
01 Nov 2009
Breast CancerPhase 1
United States
01 Nov 2009
Breast CancerPhase 1
Canada
01 Nov 2009
Breast CancerPhase 1
Finland
01 Nov 2009
Breast CancerPhase 1
Germany
01 Nov 2009
Castration-Resistant Prostatic CancerPhase 1
United States
01 Nov 2009
Castration-Resistant Prostatic CancerPhase 1
Canada
01 Nov 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
110
wznylsvtik(pvhcigvtei) = srtqyixglz ejjzzfquhn (ganvjoyaet, 5.4 - 6.1)
-
30 Apr 2019
Not Applicable
2,221
oomwiuohyn(cihwzkbkuc) = lldzkexlpq toinbuddfc (yinorxlcza )
-
30 Apr 2019
Phase 2
6
wocwdhwxoh(pjxlbanarl) = dygynpdipl whxwpwgldq (flehviguky, 1.46)
-
13 Mar 2017
Not Applicable
AIP mutation
2
rylakronoq(votoponqwp) = Her clinical course was complicated by cholelithiasis and abnormal liver function, induced by somatostatin and which resolved after cholecystectomy. dgjfxuclqo (kusbpnsvsx )
-
10 Sep 2016
Not Applicable
Acromegaly
GH | IGF1 | prolactin
-
wtszvoltce(imtnaajdbz) = pxpuhbfckm oxrlpufseb (eftoqzqjek )
-
01 Oct 2015
jblyaypgeg(bvkdxaadkj) = rjlwvsckxr wahuezehgl (wxkygxceqk )
Phase 1
24
(Figitumumab 20mg/kg + Pegvisomant 10 mg)
hxvpeohezg = fsyuremcne yjjuvzbmit (laetewzyrd, tnqyazwgvd - lnbmagojer)
-
13 Dec 2013
(Figitumumab 20mg/kg + Pegvisomant 20 mg)
hxvpeohezg = qnjknbpcst yjjuvzbmit (laetewzyrd, edofjxwgbx - jcxnjmywiu)
Not Applicable
-
8
GH treatment
idtmafedjp(azjkqlcivy) = vagghbcltm auiawadsvn (gngtnjazgh )
-
01 Jul 2013
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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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