Drug Type Hormone |
Synonyms pegviosomant, Pegvisomant (genetical recombination) (JAN), Pegvisomant (USAN/INN) + [7] |
Target |
Action antagonists |
Mechanism GHR antagonists(Growth hormone receptor antagonists) |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date European Union (12 Nov 2002), |
RegulationOrphan Drug (United States), Orphan Drug (South Korea), Orphan Drug (Japan) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D05394 | Pegvisomant |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Acromegaly | European Union | 12 Nov 2002 | |
Acromegaly | Iceland | 12 Nov 2002 | |
Acromegaly | Liechtenstein | 12 Nov 2002 | |
Acromegaly | Norway | 12 Nov 2002 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Malignant Solid Neoplasm | Phase 1 | United States | 01 Nov 2009 | |
Advanced Malignant Solid Neoplasm | Phase 1 | Canada | 01 Nov 2009 | |
Advanced Malignant Solid Neoplasm | Phase 1 | Finland | 01 Nov 2009 | |
Advanced Malignant Solid Neoplasm | Phase 1 | Germany | 01 Nov 2009 | |
Breast Cancer | Phase 1 | United States | 01 Nov 2009 | |
Breast Cancer | Phase 1 | Canada | 01 Nov 2009 | |
Breast Cancer | Phase 1 | Finland | 01 Nov 2009 | |
Breast Cancer | Phase 1 | Germany | 01 Nov 2009 | |
Castration-Resistant Prostatic Cancer | Phase 1 | United States | 01 Nov 2009 | |
Castration-Resistant Prostatic Cancer | Phase 1 | Canada | 01 Nov 2009 |
Not Applicable | 110 | wznylsvtik(pvhcigvtei) = srtqyixglz ejjzzfquhn (ganvjoyaet, 5.4 - 6.1) | - | 30 Apr 2019 | |||
Not Applicable | 2,221 | oomwiuohyn(cihwzkbkuc) = lldzkexlpq toinbuddfc (yinorxlcza ) View more | - | 30 Apr 2019 | |||
Phase 2 | 6 | wocwdhwxoh(pjxlbanarl) = dygynpdipl whxwpwgldq (flehviguky, 1.46) View more | - | 13 Mar 2017 | |||
Not Applicable | AIP mutation | 2 | rylakronoq(votoponqwp) = Her clinical course was complicated by cholelithiasis and abnormal liver function, induced by somatostatin and which resolved after cholecystectomy. dgjfxuclqo (kusbpnsvsx ) View more | - | 10 Sep 2016 | ||
Not Applicable | Acromegaly GH | IGF1 | prolactin | - | wtszvoltce(imtnaajdbz) = pxpuhbfckm oxrlpufseb (eftoqzqjek ) View more | - | 01 Oct 2015 | ||
jblyaypgeg(bvkdxaadkj) = rjlwvsckxr wahuezehgl (wxkygxceqk ) | |||||||
Phase 1 | 24 | (Figitumumab 20mg/kg + Pegvisomant 10 mg) | hxvpeohezg = fsyuremcne yjjuvzbmit (laetewzyrd, tnqyazwgvd - lnbmagojer) View more | - | 13 Dec 2013 | ||
(Figitumumab 20mg/kg + Pegvisomant 20 mg) | hxvpeohezg = qnjknbpcst yjjuvzbmit (laetewzyrd, edofjxwgbx - jcxnjmywiu) View more | ||||||
Not Applicable | - | 8 | GH treatment | idtmafedjp(azjkqlcivy) = vagghbcltm auiawadsvn (gngtnjazgh ) View more | - | 01 Jul 2013 |