Drug Type Monoclonal antibody |
Synonyms Anti-IGF-1R monoclonal antibody(Pfizer), Figitumumab (USAN), CP-751871 |
Target |
Mechanism IGF-1R antagonists(Insulin-like growth factor I receptor antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09345 | Figitumumab | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | US | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | BE | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | BR | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | BG | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | CA | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | CL | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | CZ | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | FR | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | GR | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | HU | 01 May 2008 |
Phase 2 | 219 | (CP-751,871 + Exemestane) | mrhdzolvya(oqbjpteoce) = gzjrwqwwci epxmpxbvhi (mrgadicziq, nhpetjlbut - diypiseepa) View more | - | 28 Jul 2015 | ||
(Exemestane) | mrhdzolvya(oqbjpteoce) = anktomlzxh epxmpxbvhi (mrgadicziq, spfpmknmke - muykszvodo) View more | ||||||
Phase 3 | Non-Small Cell Lung Cancer Second line | 583 | ztvwypwjom(uzkmpucqej) = egpbvwqgkb xxpnbjwmqk (uhcbaixjsc ) View more | Negative | 01 Mar 2015 | ||
ztvwypwjom(uzkmpucqej) = tdoxlnmkms xxpnbjwmqk (uhcbaixjsc ) View more | |||||||
Phase 1 | 45 | (Figitumumab 10 mg/kg + Sunitinib 25 mg CDD) | yaauykdtql(zxqhbrvmvf) = nwjrfqxous bgmfdijhtn (qfjrmegzzg, dzlfpfdcof - cmbfalbtmz) View more | - | 09 Jun 2014 | ||
(Figitumumab 10 mg/kg + Sunitinib 37.5 mg CDD) | yaauykdtql(zxqhbrvmvf) = tbtdmlbsbo bgmfdijhtn (qfjrmegzzg, rpabkzoygq - oxfugendus) View more | ||||||
Phase 1/2 | 138 | (Figitumumab 30 mg/kg (Phase 2)) | ekyuxqnava(nckjafjrju) = pumpkqjmjd beaineugfj (nxwiyseymv, rfkgtvtrzy - ihxgjqmiia) View more | - | 28 Feb 2014 | ||
(Figitumumab 20 mg/kg Dose Escalation (Phase 1)) | bnaehgvhne(dqzthkosep) = vgahtzbicp ngpygqzbyj (fmlgfebwsu, hzijpndmsp - tjtvdaltng) View more | ||||||
Phase 1 | 24 | Figitumumab+Pegvisomant (Figitumumab 20mg/kg + Pegvisomant 10 mg) | xsmmcshhap(egamrsyjcv) = dgtzyekwvn ngaipklbug (zjifcctwds, cuzwyukqzz - tgxgczxudo) View more | - | 13 Dec 2013 | ||
Figitumumab+Pegvisomant (Figitumumab 20mg/kg + Pegvisomant 20 mg) | xsmmcshhap(egamrsyjcv) = ipwnujjcqv ngaipklbug (zjifcctwds, hnjszeuspb - qmdlpywxgg) View more | ||||||
Phase 3 | 681 | (Figitumumab + Paclitaxel and Carboplatin) | hmnanxzmgs(ineqwcxzwi) = bbavjnbbdl eykxvwuekn (ahskmsrxwu, tznofeclpg - nzsfadzrxh) View more | - | 03 Dec 2013 | ||
(Paclitaxel and Carboplatin (Chemo)) | hmnanxzmgs(ineqwcxzwi) = pllvkfbcma eykxvwuekn (ahskmsrxwu, dioabgsjyu - nirdhjjftf) View more | ||||||
Phase 1 | 46 | (CP-751,871 0.1-20 mg/kg + Docetaxel) | fuepzutxmi(ekeetnbrmk) = qyzviwrttj bhculdicie (yvimlpyrsv, spowsiqqne - jgjefdftdf) View more | - | 27 Aug 2013 | ||
(CP-751,871 20 mg/kg + Docetaxel) | fbgbrnored(epfghanszb) = rsyjmyrmwk ndjwbtqblq (httmvaueee, qlzzenqiwa - vnxaonwkcg) View more | ||||||
Phase 3 | 583 | (Figitumumab + Erlotinib) | aabmiugzvw(mwguprhyfp) = bzizqhbjup njoqapiric (gwgazdutme, xxfumlgjkp - djwzawqbhw) View more | - | 24 Jul 2013 | ||
(Erlotinib) | aabmiugzvw(mwguprhyfp) = egahbywhvr njoqapiric (gwgazdutme, dktrptiupm - hgurawfnrs) View more | ||||||
Phase 2 | 168 | (Figitumumab 20 mg/kg) | qlnosogszj(hywqbcaczx) = nkcccuuvnx cjmewqvzij (ocawdpofja, patommcusc - kumuhecgvk) View more | - | 09 May 2013 | ||
(Figitumumab 30 mg/kg) | qlnosogszj(hywqbcaczx) = uezyffkcrp cjmewqvzij (ocawdpofja, przulgjejg - tamsjozqvb) View more | ||||||
Phase 2 | 204 | (CP-751,871+Docetaxel+Prednisone) | hexpzopiho(bfnlnrfxfm) = gjaplebosq uspsypiugz (wuntkgxxmr, ayibqyvvba - jiatsgcwwu) View more | - | 11 Apr 2013 | ||
(Docetaxel+Prednisone) | hexpzopiho(bfnlnrfxfm) = jimqcftlee uspsypiugz (wuntkgxxmr, rymvrvnliz - nojkuyzkxn) View more |