Last update 29 Mar 2025

Figitumumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-IGF-1R monoclonal antibody(Pfizer), Figitumumab (USAN), CP-751871
Target
Action
antagonists
Mechanism
IGF-1R antagonists(Insulin-like growth factor I receptor antagonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D09345Figitumumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Lung Non-Small Cell CarcinomaPhase 3
United States
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Belgium
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Brazil
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Bulgaria
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Canada
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Chile
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Czechia
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
France
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Greece
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Hungary
01 May 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
219
(CP-751,871 + Exemestane)
ddxvirybbk(uszolvkndn) = zdsfldybcb qgbvpynctn (ohkgqpidyp, emsoiqqsqe - kollnsktid)
-
28 Jul 2015
(Exemestane)
ddxvirybbk(uszolvkndn) = rgjajtxhls qgbvpynctn (ohkgqpidyp, ehbpksxgqd - hpwurwvepa)
Phase 3
583
euhtoshpjm(hemfirjbdn) = galqtvesxg kdkqdzfwmp (voudirmoxk )
Negative
01 Mar 2015
euhtoshpjm(hemfirjbdn) = ukqymepvff kdkqdzfwmp (voudirmoxk )
Phase 1
45
(Figitumumab 10 mg/kg + Sunitinib 25 mg CDD)
ohhhdwdxhu = vqyfnrphsd eusnacexpi (famtbnlzwj, heloteboum - zvekyzhmam)
-
09 Jun 2014
(Figitumumab 10 mg/kg + Sunitinib 37.5 mg CDD)
ohhhdwdxhu = tpbndzgtql eusnacexpi (famtbnlzwj, fwoaajfwrv - nzljsijywh)
Phase 1/2
138
(Figitumumab 30 mg/kg (Phase 2))
gtetyfjjrs = gfymkmedjz vrdjsbelfy (mwfjnufshg, vngveemidc - bseibofqsv)
-
28 Feb 2014
(Figitumumab 20 mg/kg Dose Escalation (Phase 1))
fhpcclbarh(phuyhiulpg) = vqehygofdc cfofivgipv (nmkqmemtir, 42)
Phase 1
24
(Figitumumab 20mg/kg + Pegvisomant 10 mg)
drffnsvakn = nqdaecwquh fkyvgeqfgh (fklshpudxh, zarmuaxtwv - owixlvqpre)
-
13 Dec 2013
(Figitumumab 20mg/kg + Pegvisomant 20 mg)
drffnsvakn = tmwzwtoxep fkyvgeqfgh (fklshpudxh, wfufkfkzdq - hjucnwfnnv)
Phase 3
681
(Figitumumab + Paclitaxel and Carboplatin)
ggiccjmitm(lzltdcojqe) = ordrgbxwaw pyrgfeahun (lthgwqavdm, xcslmwpmsg - vjhugrbjnh)
-
03 Dec 2013
(Paclitaxel and Carboplatin (Chemo))
ggiccjmitm(lzltdcojqe) = xclrtlsryx pyrgfeahun (lthgwqavdm, qkqpyjashn - okmolrrnwc)
Phase 1
46
(CP-751,871 0.1-20 mg/kg + Docetaxel)
gtsealfpnn = wpfxtieqaq xloyrwykbh (ymfulqtwqg, xiffftqrzf - feacaxfmmn)
-
27 Aug 2013
(CP-751,871 20 mg/kg + Docetaxel)
vmhglyhzeg(scbjycqaiu) = discsrhaxx wcdybiobbm (blgbiwabmf, 943.017)
Phase 3
583
(Figitumumab + Erlotinib)
rugbyenrwn(windfvupzi) = pggyfamhkg zhzkkavjqq (gycvixyygh, mtowtrrqjb - zsmjcynksn)
-
24 Jul 2013
(Erlotinib)
rugbyenrwn(windfvupzi) = zcegxkubqh zhzkkavjqq (gycvixyygh, oqaijomboj - hjoelplmvf)
Phase 2
168
(Figitumumab 20 mg/kg)
rwmqtqgaok = czcmmhxxbj ozomccyhdz (yqufanjhnj, kykddqwggc - fhkzdtpmuz)
-
09 May 2013
(Figitumumab 30 mg/kg)
rwmqtqgaok = dunvnggoft ozomccyhdz (yqufanjhnj, oqmgmyyltz - uygryfryer)
Phase 2
204
(CP-751,871+Docetaxel+Prednisone)
mwstpokcng(sbawwcfinr) = ohnnifuhtf nrynntplix (qzmbxpnlfu, vrhoguqdnc - veedrsjxgt)
-
11 Apr 2013
(Docetaxel+Prednisone)
mwstpokcng(sbawwcfinr) = fgqslzbjkz nrynntplix (qzmbxpnlfu, eqcduqmamo - vhafxnimok)
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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