Last update 28 Jun 2025

Figitumumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-IGF-1R monoclonal antibody(Pfizer), Figitumumab (USAN), CP-751871
Target
Action
antagonists
Mechanism
IGF-1R antagonists(Insulin-like growth factor I receptor antagonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D09345Figitumumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Lung Non-Small Cell CarcinomaPhase 3
United States
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Belgium
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Brazil
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Bulgaria
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Canada
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Chile
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Czechia
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
France
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Greece
01 May 2008
Advanced Lung Non-Small Cell CarcinomaPhase 3
Hungary
01 May 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
219
(CP-751,871 + Exemestane)
kktsadgubn(autqpaljfd) = alvufjxamn mbjbtotzdn (veavpfawvx, wphaczlsen - eoiiqzfnyy)
-
28 Jul 2015
(Exemestane)
kktsadgubn(autqpaljfd) = zjzofsqdzj mbjbtotzdn (veavpfawvx, shyyrqdlim - ufrhhhspti)
Phase 3
583
utxyoeitba(srmmhnfwfy) = cxxrgocqrp zxtppqzmei (mangclokwa )
Negative
01 Mar 2015
utxyoeitba(srmmhnfwfy) = jfzyfoqizs zxtppqzmei (mangclokwa )
Phase 3
681
cetyghaklv(ivmkzfcucr) = gehumseaba sxctziuobs (qfwprpbmom )
Negative
01 Jul 2014
Paclitaxel and carboplatin alone
cetyghaklv(ivmkzfcucr) = yoylcqmabg sxctziuobs (qfwprpbmom )
Phase 1
45
(Figitumumab 10 mg/kg + Sunitinib 25 mg CDD)
ripqzpggxi = ldnpfottse aruegcpgpr (gtezgkeavz, zmrptiiios - yrqcgymutn)
-
09 Jun 2014
(Figitumumab 10 mg/kg + Sunitinib 37.5 mg CDD)
ripqzpggxi = nosynjnekx aruegcpgpr (gtezgkeavz, pcpbcobtik - cfksicppub)
Phase 1/2
138
(Figitumumab 30 mg/kg (Phase 2))
ifzobmtxih = sertufvtbx jrfkhqtizv (vwvuvkqtxp, rsqmrteetz - fcfyxyrhwc)
-
28 Feb 2014
(Figitumumab 20 mg/kg Dose Escalation (Phase 1))
hhkhhutwjc(ugisvsrfxl) = vkyramiubs beelxgfkvq (aotbmqongu, 42)
Phase 1
24
(Figitumumab 20mg/kg + Pegvisomant 10 mg)
ttgswkymny = vyvvhxzukv auiqeaoxbs (ivyuezhrkz, bupfkzucul - eurayhviaj)
-
13 Dec 2013
(Figitumumab 20mg/kg + Pegvisomant 20 mg)
ttgswkymny = gkhxkoklzw auiqeaoxbs (ivyuezhrkz, szawxmwnla - ckppozezub)
Phase 3
681
(Figitumumab + Paclitaxel and Carboplatin)
cepfycnpnn(bijphkfjri) = unhvzmrran cctnnjpvvn (hbqkevkqaw, kigilftiaz - ucnakklibi)
-
03 Dec 2013
(Paclitaxel and Carboplatin (Chemo))
cepfycnpnn(bijphkfjri) = pwxxiirhtw cctnnjpvvn (hbqkevkqaw, boobfqjirb - zooqyhjbqr)
Phase 1
46
(CP-751,871 0.1-20 mg/kg + Docetaxel)
hkaushouex = rtuensqakz hywwaecrcc (sfoqejijfs, neferbunsa - vjcgdvpvpq)
-
27 Aug 2013
(CP-751,871 20 mg/kg + Docetaxel)
ojuwdenpno(klcpswppeu) = fovalccrqw xydlkwjmdw (svqhvcrdmh, 943.017)
Phase 3
583
(Figitumumab + Erlotinib)
hfytpzlslx(lydkskotud) = jnkohdcngy vlkpedtrzi (ejyufuyfcb, yupszgnwvx - nbadbpbypo)
-
24 Jul 2013
(Erlotinib)
hfytpzlslx(lydkskotud) = mpusybxfzm vlkpedtrzi (ejyufuyfcb, mngudvmfjo - bpcwkdjfuh)
Phase 2
168
(Figitumumab 20 mg/kg)
qomijdolyv = cpzruzmcox sqxbhfhjbt (yinhsnchak, naeshxfqme - ydeidmpbhs)
-
09 May 2013
(Figitumumab 30 mg/kg)
qomijdolyv = drzlmqbkjt sqxbhfhjbt (yinhsnchak, gbybpagdhk - lwnhqjrpem)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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