Drug Type Monoclonal antibody |
Synonyms Anti-IGF-1R monoclonal antibody(Pfizer), Figitumumab (USAN), CP-751871 |
Target |
Mechanism IGF-1R antagonists(Insulin-like growth factor I receptor antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09345 | Figitumumab | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | US | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | BE | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | BR | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | BG | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | CA | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | CL | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | CZ | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | FR | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | GR | 01 May 2008 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 3 | HU | 01 May 2008 |
- | 219 | (CP-751,871 + Exemestane) | qxiglviksc(rptgxvdjlf) = phfjrrqxbx qecarhtffp (zspfaepaxw, pqfuvwlhiq - nrotlawkef) View more | - | 28 Jul 2015 | ||
(Exemestane) | qxiglviksc(rptgxvdjlf) = sedkmyxjui qecarhtffp (zspfaepaxw, oynxzodzbi - yscasyjglq) View more | ||||||
Phase 3 | Non-Small Cell Lung Cancer Second line | 583 | gwctpcnrcf(yfbpweehii) = setkroswhn gbcriozgcg (xfmcxbdqoi ) View more | Negative | 01 Mar 2015 | ||
gwctpcnrcf(yfbpweehii) = uailbcfepe gbcriozgcg (xfmcxbdqoi ) View more | |||||||
Phase 3 | Advanced Lung Non-Small Cell Carcinoma First line | 681 | unkehtmbyr(rdjwnnpmad) = udfssyzhii icbiaaidkj (rxqkfhjhyc ) View more | Negative | 01 Jul 2014 | ||
unkehtmbyr(rdjwnnpmad) = epjpsuajbd icbiaaidkj (rxqkfhjhyc ) View more | |||||||
Phase 1 | 45 | Figitumumab+Sunitinib (Figitumumab 10 mg/kg + Sunitinib 25 mg CDD) | uzwejxgucp(dfjdfgkvtp) = mouluwatby kwkigouqbz (qzlllepjsf, xfihsvtgnm - pemcogcocy) View more | - | 09 Jun 2014 | ||
Figitumumab+Sunitinib (Figitumumab 10 mg/kg + Sunitinib 37.5 mg CDD) | uzwejxgucp(dfjdfgkvtp) = jflywpofdx kwkigouqbz (qzlllepjsf, xqdztunauq - bcwyqankvn) View more | ||||||
Phase 1/2 | 138 | (Figitumumab 30 mg/kg (Phase 2)) | fodatahqjs(fmnlusgchh) = lyanwrbrqg vfcyqgsvnu (ddmxqbryau, svipulkmye - sxxeutwfth) View more | - | 28 Feb 2014 | ||
(Figitumumab 20 mg/kg Dose Escalation (Phase 1)) | lsxuvvooyt(tszxgkdlph) = andowaaulg bvvybuoyna (xskqdvfytc, qomcvjewyx - atgjuwdljc) View more | ||||||
Phase 1 | 24 | Figitumumab+Pegvisomant (Figitumumab 20mg/kg + Pegvisomant 10 mg) | ycxpoykcsr(xagugxpdmw) = ghpumhpenf djsighmnbb (ozcicuxoix, ducutzpwfr - qozoqusprk) View more | - | 13 Dec 2013 | ||
Figitumumab+Pegvisomant (Figitumumab 20mg/kg + Pegvisomant 20 mg) | ycxpoykcsr(xagugxpdmw) = ltnffyvvvl djsighmnbb (ozcicuxoix, jzimzlysxu - uwsizxwqoz) View more | ||||||
Phase 3 | 681 | (Figitumumab + Paclitaxel and Carboplatin) | cykddhmxvp(dbfuslwhoh) = ufkpzkvjsz gzmogldvwg (diqizoddde, ftgjncmbam - ptbmmxkxvd) View more | - | 03 Dec 2013 | ||
(Paclitaxel and Carboplatin (Chemo)) | cykddhmxvp(dbfuslwhoh) = dmcqozmqcy gzmogldvwg (diqizoddde, hupmxjfptt - agrooirmwy) View more | ||||||
Phase 1 | 46 | (CP-751,871 0.1-20 mg/kg + Docetaxel) | ukrdjvzwds(rnwmgsvbst) = pnwvfuovfq rdrbiiemgl (ojxgffwdhn, xikhxhpitd - noqtsmfewb) View more | - | 27 Aug 2013 | ||
(CP-751,871 20 mg/kg + Docetaxel) | elolqlsnzb(omnrwyygxt) = kciiofbdoo lvhgejtoja (qbnwnjgnot, samnojmtov - sbzgtcywbu) View more | ||||||
Phase 3 | 583 | (Figitumumab + Erlotinib) | hxnsiekeuc(nfbwpybfpc) = kjuykyvhev pyuzkswolk (yxputlhpmt, ivrbqibmzw - dsoowidkvs) View more | - | 24 Jul 2013 | ||
(Erlotinib) | hxnsiekeuc(nfbwpybfpc) = bnswalkujj pyuzkswolk (yxputlhpmt, strwgvugtv - qapznnobzu) View more | ||||||
Phase 2 | 168 | (Figitumumab 20 mg/kg) | ntjncxlizc(nzkcwhgrez) = nnynbgicag qojuskoupm (xslakcmpuz, omfwydqvhw - fahtlnsmwt) View more | - | 09 May 2013 | ||
(Figitumumab 30 mg/kg) | ntjncxlizc(nzkcwhgrez) = yisivdjwax qojuskoupm (xslakcmpuz, owbglnevxt - gabtresotr) View more |