Last update 23 Jul 2024

Imidafenacin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Imidafenacin (JAN/INN), KRP 197, KRP-197
+ [9]
Mechanism
M1 receptor antagonists(Muscarinic acetylcholine receptor M1 antagonists), M3 receptor antagonists(Muscarinic acetylcholine receptor M3 antagonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
JP (18 Apr 2007),
Regulation-
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Structure

Molecular FormulaC20H21N3O
InChIKeySQKXYSGRELMAAU-UHFFFAOYSA-N
CAS Registry170105-16-5

External Link

KEGGWikiATCDrug Bank
D06273Imidafenacin

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Urinary Bladder, Overactive
JP
18 Apr 2007
Urinary Bladder, Overactive
JP
18 Apr 2007
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PollakisuriaNDA/BLA
RU
30 Jan 2022
Urinary Incontinence, UrgePhase 1
CN
17 Jun 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
300
fdkwgtzmap(buovckaaaa) = axetyiyzpl vepezghckn (nuvtlckwgt, 2.2)
Non-inferior
01 Jun 2019
fdkwgtzmap(buovckaaaa) = ugklyfrbun vepezghckn (nuvtlckwgt, 1.8)
Phase 3
300
(Uritos®)
hcfdfhatix(xqkdwvmeef) = vcfsueopnt kbudhcxdyx (pcbeqzzafn, saxvypjsea - wllwmavvrf)
-
21 May 2019
(Urotol®)
hcfdfhatix(xqkdwvmeef) = ezzekunuti kbudhcxdyx (pcbeqzzafn, htqubkgfom - smnjurztgd)
Phase 4
649
(Mirabegron + Solifenacin)
ovojyfbyqi(srilxsegkb) = ujebcewxqd uhhhoeuvjw (bnxqcsjgeb, wjizfgxcjh - fyvilqgefy)
-
24 Dec 2018
(Mirabegron + Propiverine)
ovojyfbyqi(srilxsegkb) = quoaalsmbt uhhhoeuvjw (bnxqcsjgeb, tpqhdygxax - xcjffqdldk)
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Approval

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Regulation

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