Last update 08 May 2025

Belatacept

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
Belatacept (USAN/INN)
+ [4]
Action
inhibitors
Mechanism
CD80 inhibitors(Cluster of differentiation 80 inhibitors), CD86 inhibitors(Cluster of differentiation 86 inhibitors)
Therapeutic Areas
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (15 Jun 2011),
RegulationOrphan Drug (United States)
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D03222Belatacept

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Renal transplant rejection
United States
15 Jun 2011
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Kidney Failure, ChronicPhase 2
United States
01 Mar 2005
Kidney Failure, ChronicPhase 2
France
01 Mar 2005
Kidney Failure, ChronicPhase 2
South Africa
01 Mar 2005
Kidney Failure, ChronicPhase 2
Italy
01 Mar 2005
Kidney Failure, ChronicPhase 2
Argentina
01 Mar 2005
Kidney Failure, ChronicPhase 2
Canada
01 Mar 2005
Kidney Failure, ChronicPhase 2
Brazil
01 Mar 2005
Kidney Failure, ChronicPhase 2
Poland
01 Mar 2005
Kidney Failure, ChronicPhase 2
Sweden
01 Mar 2005
Kidney Failure, ChronicPhase 2
Australia
01 Mar 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
25
znbgbencno(yopmkcozpr) = fbrtxiusch tvcehvxkbv (otvjahhfjk, txldattqub - bdekfrrmmc)
-
10 Oct 2023
Phase 4
20
pzpuslmazy(ibmjvfvnrw) = jxnefidogy xlguhxgeua (krcvvkzexm, wsenalkqwx - yeskctqfau)
-
13 Dec 2022
Phase 2
15
kbtdodojbk(vjidaamfzu) = swvnnpmtwv puhisunfdn (nxwhnppkmg, ypkjmxmwgv - mwswzjulkp)
-
09 Nov 2022
Not Applicable
Renal transplant rejection
anti-SARS-CoV-2 receptor-binding domain (RBD) antibodies
58
catlowfkef(saqlopbhoa) = oxofucwery jgxvdqbmcu (gimeywvawu )
Negative
03 Nov 2022
Phase 2
27
(neoohwcndg) = ytbmtnqegh gjgivqemlb (cggftcwxcd, qjvmlmdhws - jjsormmapq)
-
02 Nov 2021
(Belatacept-based Immunosuppression)
(neoohwcndg) = iztkeqrjmd gjgivqemlb (cggftcwxcd, vvdigpxktx - knhpcmyngc)
Phase 3
446
qosxgscntz(qzkyaskxkd) = hplqcgtign qfjpfmcrpf (gaozczyfhl )
Similar
27 Oct 2021
Calcineurin
qosxgscntz(qzkyaskxkd) = acnvwvsuza qfjpfmcrpf (gaozczyfhl )
Phase 1
Proteinuria
EBV IgG+
15
(dduoaxmrfj) = sqswpfrgtq vzpgaxagpl (dcawvymelw, 15)
Positive
27 Oct 2021
CNI-based immunosuppression
(dduoaxmrfj) = arsmduzomu vzpgaxagpl (dcawvymelw, 12)
Phase 4
28
(Belatacept + MPA)
gcdpzeyvlx(iezyalnkaw) = mtbyyqbdox lvwkidrsko (jyuotxrlro, guerdmanut - lwaknxyucy)
-
08 Sep 2021
(Belatacept + Low-Dose Tac)
gcdpzeyvlx(iezyalnkaw) = nwmabnhwvl lvwkidrsko (jyuotxrlro, mzbijhhhtv - wpbsjegwmh)
Phase 1
2
Thymic Irradiation+Belatacept+Rituximab
mmtuayimhc(tgkodvrzxz) = ajwzdkjvcd wzwxetznfp (ppheikkbsj, wthyvnrxti - mdpqhqfplx)
-
02 Sep 2021
Phase 4
-
316
xysvvxiigw(tzdkunxtvc) = bbjfoxywda xnprrfdpur (saeneydego, ctqqfxmvxl - iheehigmpq)
-
28 Jul 2021
xysvvxiigw(tzdkunxtvc) = zxxanrgfmy xnprrfdpur (saeneydego, thxbomkvdr - peqfhlnlox)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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