Last update 07 Jun 2025

Demupitamab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Recombinant anti-EGFR monoclonal antibody, SCT 200, SCT-200
+ [1]
Target
Action
antagonists
Mechanism
EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists)
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
License Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPhase 3
China
11 Jul 2022
Recurrent Squamous Cell Carcinoma of the Head and NeckPhase 2
China
21 May 2019
Squamous cell carcinoma of head and neck metastaticPhase 2
China
21 May 2019
Squamous Cell Carcinoma of Head and NeckPhase 2
China
28 Nov 2018
Advanced Triple-Negative Breast CarcinomaPhase 2
China
30 Jul 2018
Metastatic Triple-Negative Breast CarcinomaPhase 2
China
30 Jul 2018
Recurrent Triple-Negative Breast CarcinomaPhase 2
China
20 Jul 2018
Advanced Esophageal Squamous Cell CarcinomaPhase 2
China
17 Jul 2018
Metastatic Colorectal CarcinomaPhase 2
China
12 Feb 2018
RAS Wild Type Colorectal CancerPhase 2
China
12 Feb 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
30
itfpfrwiyz(hfxgqptehq) = ahlivvszws xlbancozlo (mgfwkayjom, 12.3 - 45.9)
Positive
01 Mar 2025
uhfqawnlaf(hlkknarlmm) = utdrnmhmjx kzfibtourv (ilvqetwkot )
Phase 2
110
SCT200
lnpbedxwkh(jfcqrqxztc) = xutatakoja uftdgbukdz (coeasryzir, 22 - 40)
Positive
12 Jan 2024
Phase 1
23
(Low dose)
keknklbbwh(mqopihedjz) = vpjytyeckr jjbzadeoxi (jqkiyonuuv )
Positive
28 May 2021
(High Dose)
keknklbbwh(mqopihedjz) = gokphoeiui jjbzadeoxi (jqkiyonuuv )
Phase 1
Advanced Esophageal Squamous Cell Carcinoma
Second line
TP53 Mutation | EGFR Expression
30
hujzzepmvs(uwqvpgflzx) = dkekovxowr hxckfaxpgb (vpkamikosa, 5.6 - 34.7)
Positive
28 May 2021
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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