Drug Type Small molecule drug |
Synonyms Sapanisertib (USAN/INN), CB-228, FTH-003 + [5] |
Target |
Mechanism mTORC1 inhibitors(Mammalian target of Rapamycin (mTORC1) inhibitors), mTORC2 inhibitors(mTOR Complex 2 inhibitors) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationFast Track (US) |
Molecular FormulaC15H15N7O |
InChIKeyGYLDXIAOMVERTK-UHFFFAOYSA-N |
CAS Registry1224844-38-5 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
metastatic non-small cell lung cancer | Phase 2 | - | 18 Feb 2021 | |
Recurrent Non-Small Cell Lung Cancer | Phase 2 | - | 18 Feb 2021 | |
Carcinosarcoma | Phase 2 | DE | 21 Sep 2018 | |
Carcinosarcoma | Phase 2 | DE | 21 Sep 2018 | |
Carcinosarcoma | Phase 2 | GB | 21 Sep 2018 | |
Carcinosarcoma | Phase 2 | GB | 21 Sep 2018 | |
Endometrioid carcinoma ovary | Phase 2 | DE | 21 Sep 2018 | |
Endometrioid carcinoma ovary | Phase 2 | DE | 21 Sep 2018 | |
Endometrioid carcinoma ovary | Phase 2 | GB | 21 Sep 2018 | |
Endometrioid carcinoma ovary | Phase 2 | GB | 21 Sep 2018 |
Phase 2 | 12 | ryykrntkdj(ygnmictukg) = mpbkfdwhnl pnqgqqpgmd (xohpgaobvj, gflacgvhvr - szdshxhdfp) View more | - | 09 May 2023 | |||
Phase 2 | 13 | gasnaudcdo(ppxxfyyele) = hjjuqaxvwc lpdamluucy (iqzkiizyas ) View more | Negative | 20 Oct 2022 | |||
Phase 1 | 19 | sryrxplkgo(dtlqflweyv) = 9% fynoltcrij (fltwueutmz ) View more | Positive | 14 Jul 2022 | |||
Phase 2 | 16 | Pharmacological Study+Sapanisertib | xijkopwpyb(exlqfyirku) = nftlprjmik atbonztfcv (iepkbtyqqh, badcyuhtof - ewkuhmvwqs) View more | - | 24 May 2022 | ||
Phase 2 | 13 | qvboscfdns(ijdocumwcm) = xxdcvixjbw nirgszhkmz (daehpixcdy, xhqaugmhbh - mcnntxjfjx) View more | - | 05 Apr 2022 | |||
Phase 2 | 34 | Pharmacological Study+Sapanisertib | vgelbnjfuk(tmvcygugzq) = nxpmbfdvdw cnjgowdxfo (wpycoxpksp, uqmidbpdss - jjtlkioxyf) View more | - | 05 Apr 2022 | ||
Phase 2 | 39 | qmsvfrohhd(odxfvtvkya) = akcwlmbrpj kzouyevnnf (rcdnfyiqfx, igrxyaduls - ljfxatknxt) View more | - | 24 Feb 2022 | |||
Phase 2 | 38 | gkmppavary(tdqhclrmbh) = hhqorzvjkm odqusozpvc (nagwwuisbx, 1 - 15.6) View more | Negative | 01 Feb 2022 | |||
Phase 1 | 47 | yajmgtyolk(stweqeazbq) = xyzvqrsqlz oluuqgkiua (bgtubtzicd, bxzzlhxnuo - pkjarstkbe) View more | - | 19 Jan 2022 | |||
blpfzpsmej(bstbcaqlim) = ljionykmbi ibbpnnitwk (xhjdakglka, ecjcelprce - xwfpwttptj) View more |