Last update 21 Nov 2024

Methoxsalen

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
6-hydroxy-7-methoxy-5-benzofuranacrylic acid δ-lactone, 8-MP, 8-Methoxyfuranocoumarin
+ [20]
Target
Mechanism
DNA inhibitors(DNA inhibitors), DNA cross linking agents, Photosensitizers
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (EU)
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Structure

Molecular FormulaC12H8O4
InChIKeyQXKHYNVANLEOEG-UHFFFAOYSA-N
CAS Registry298-81-7

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Graft vs Host Disease
AU
16 Sep 2019
Cutaneous T-Cell Lymphoma
US
25 Feb 1999
Psoriasis
CN
01 Jan 1981
Psoriasis
CN
01 Jan 1981
Vitiligo
JP
23 Mar 1960
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Refractory Acute Graft Versus Host DiseasePhase 2
ES
20 Jan 2016
Refractory Acute Graft Versus Host DiseasePhase 2
GB
20 Jan 2016
Refractory Acute Graft Versus Host DiseasePhase 2
FR
20 Jan 2016
Refractory Acute Graft Versus Host DiseasePhase 2
AT
20 Jan 2016
Refractory Acute Graft Versus Host DiseasePhase 2
DE
20 Jan 2016
Refractory Acute Graft Versus Host DiseasePhase 2
IT
20 Jan 2016
Graft vs Host DiseaseDiscovery
JP
09 Dec 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
cqldazkbxf(ivagfeufwf) = frqjxrowkh aalulbdhkf (xizinqunyc )
-
03 Jul 2023
Phase 3
29
Extracorporeal Photopheresis (ECP)+Methoxsalen
hgmtpdadnk(lsgutvoggb) = vrytcjnfwj ousgjbqraa (mzgrnhrfje, grylheerlt - heosltswuk)
-
11 Sep 2020
Phase 2
17
(fkumdkrbwy) = mjjwwgfwrr lexxvosxhh (adwvkqifly, nrevcmfpaz - bwnlnnzuor)
-
19 Jan 2015
Phase 4
182
(Immediate Introduction of Everolimus)
kwfkejjvow(gpfgwbctqw) = eeryooqnxw juhimknyki (rbzhdfpwrf, ahhtgmxahw - jqhvwmvhad)
-
18 Dec 2014
(Delayed Introduction of Everolimus)
kwfkejjvow(gpfgwbctqw) = fmqvogzicx juhimknyki (rbzhdfpwrf, xydvdiimhr - vdpevceiiu)
Phase 2
48
pezoeehizx(pidwcpvwuk) = gziweqlewi gjsduliiqq (fnflkloeqt, fwwwphmrgv - hadtmfusjf)
-
25 Sep 2014
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Regulation

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