Povidone-Iodine

NASHVILLE, Tenn., July 20, 2026 (GLOBE NEWSWIRE) -- Harrow (Nasdaq: HROW), a leading provider of ophthalmic disease management solutions in North America, today announced the presentation of three studies supporting IHEEZO ® (chloroprocaine HCl ophthalmic gel 3%), a broadly labeled low viscosity ocular anesthetic gel, and BYOOVIZ ® (ranibizumab-nuna) i , an FDA-approved biosimilar referencing LUCENTIS ii (ranibizumab) at the American Society of Retina Specialists (ASRS) 2026 Annual Meeting. Collectively, the presentations expand the growing body of clinical and real-world evidence supporting Harrow's retina portfolio and reinforce Harrow’s commitment to generating quality evidence that strengthens physician confidence, improves patient experience, and supports long-term product adoption and innovation. “ASRS is one of the premier scientific meetings in retina, and we're excited to share data that continues to strengthen the foundation supporting our growing retina franchise,” said Mark L. Baum, Chief Executive Officer of Harrow. “We believe durable commercial success is built on strong clinical evidence, generated before FDA-approval, and then robust supportive data sets subsequently produced. These studies further expand the evidence supporting IHEEZO while adding to the growing body of real-world experience for BYOOVIZ, reflecting our long-term commitment to retina specialists and the patients they treat.” One presentation highlighted interim findings from an investigator-initiated, prospective, randomized study of 150 patients comparing IHEEZO versus subconjunctival lidocaine. While these preliminary data represent an early look at the data, investigators observed encouraging trends toward less post-procedure pain, a better post-injection patient experience, and fewer ocular symptoms through 24 hours following intravitreal injection among patients treated with IHEEZO. Harrow believes these early findings provide an encouraging signal supporting further investigation in a larger patient population. Importantly, Harrow continues to enroll QUELL, a prospective, randomized, multi-center clinical trial of approximately 236 subjects that is being conducted under an active Investigational New Drug (IND) application. QUELL is designed to generate robust clinical evidence evaluating post-injection pain, patient experience, procedural performance, and safety in a substantially larger patient population, with topline data expected in the fourth quarter of 2026. ezstandalone.cmd.push(function () { ezstandalone.showAds(131); }); Another real-world study retrospectively evaluated whether IHEEZO's proprietary low-viscosity gel formulation interferes with antisepsis when used with chlorhexidine before intravitreal injection. Across nearly 20,000 injections, investigators observed no evidence of an increased endophthalmitis risk compared with a legacy tetracaine/povidone-iodine preparation. Although retrospective and not intended to demonstrate statistical superiority, the findings provide further confidence that physicians can realize the patient-experience benefits of IHEEZO's low-viscosity gel formulation without introducing additional procedural risk associated with antisepsis. “These studies help build the scientific foundation supporting IHEEZO,” said Amir Shojaei, Chief Scientific Officer of Harrow. “The early interim randomized data suggest the potential to improve the patient experience, while the large real-world analysis provides reassuring evidence regarding procedural safety. We look forward to completing enrollment in QUELL, which we believe will provide the most comprehensive evaluation of IHEEZO in retina to date.” Finally, Samsung Bioepis presented interim findings from a large-scale, real-world post-marketing surveillance study of BYOOVIZ. Full results from this study are being announced jointly with Samsung Bioepis today. “Between the continued expansion of the clinical evidence supporting IHEEZO, the recent launch of BYOOVIZ, and the ongoing growth of our retina franchise, we believe Harrow is increasingly well-positioned as a trusted long-term partner to retina specialists,” Baum concluded. “We appreciated the opportunity to engage with physicians throughout ASRS and look forward to sharing additional updates later this year.” IHEEZO ® (chloroprocaine hydrochloride ophthalmic gel) 3%, for topical ophthalmic use INDICATIONS AND USAGE IHEEZO is an ester anesthetic indicated for ocular surface anesthesia. IMPORTANT SAFETY INFORMATION CONTRAINDICATIONS IHEEZO is contraindicated in patients with a history of hypersensitivity to any component of this preparation WARNINGS AND PRECATIONS Not for Injection or Intraocular Administration. Corneal Injury Due to Insensitivity. Corneal Opacification For Administration by Healthcare Provider: IHEEZO is not intended for patient self-administration ADVERSE REACTIONS Most common adverse reaction is mydriasis (approximately 25%) Please see full Prescribing information BYOOVIZ ® (ranibizumab-nuna) injection, for intravitreal use is a biosimilar to LUCENTIS (ranibizumab injection) INDICATIONS AND USAGE BYOOVIZ, a vascular endothelial growth factor (VEGF) inhibitor, is indicated for the treatment of patients with: Neovascular (Wet) Age-Related Macular Degeneration (AMD) Macular Edema Following Retinal Vein Occlusion (RVO) Myopic Choroidal Neovascularization (mCNV) IMPORTANT SAFETY INFORMATION CONTRAINDICATIONS Ocular or periocular infections Hypersensitivity WARNINGS AND PRECAUTIONS Endophthalmitis and retinal detachments may occur following intravitreal injections. Patients should be monitored following the injection Increases in intraocular pressure (IOP) have been noted both pre- and post intravitreal injection There is a potential risk of arterial thromboembolic events following intravitreal use of VEGF inhibitors ADVERSE REACTIONS The most common adverse reactions (reported more frequently in ranibizumab treated subjects than control subjects) are conjunctival hemorrhage, eye pain, vitreous floaters, and increased IOP Please see full Prescribing Information About Harrow Harrow, Inc. (Nasdaq: HROW) is a leading provider of ophthalmic disease management solutions in North America, offering a comprehensive portfolio of products that address conditions affecting both the front and back of the eye, such as dry eye disease, wet (or neovascular) age-related macular degeneration, cataracts, refractive errors, glaucoma and a range of other ocular surface conditions and diseases of the retina. Harrow was founded with a commitment to deliver safe, effective, accessible, and affordable medications that enhance patient compliance and improve clinical outcomes. For more information about Harrow, please visit harrow.com and connect with us on LinkedIn . About Samsung Bioepis Co., Ltd. Established in 2012, Samsung Bioepis is a biopharmaceutical company committed to realizing healthcare that is accessible to everyone. Through innovations in product development and a firm commitment to quality, Samsung Bioepis aims to become the world's leading biopharmaceutical company. Samsung Bioepis continues to advance a broad pipeline of biologic candidates that cover a spectrum of therapeutic areas, including immunology, oncology, ophthalmology, hematology, nephrology, neurology, and endocrinology. For more information, please visit and follow us on LinkedIn and X . Forward-Looking Statements This press release contains “forward-looking statements” within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Any statements in this release that are not historical facts may be considered such “forward-looking statements.” Forward-looking statements are based on management's current expectations and are subject to risks and uncertainties which may cause results to differ materially and adversely from the statements contained herein. Some of the potential risks and uncertainties that could cause actual results to differ from those predicted include, among others, risks related to: liquidity or results of operations; our ability to successfully implement our business plan, develop and commercialize our products, product candidates and proprietary formulations in a timely manner or at all, identify and acquire additional products, manage our pharmacy operations, service our debt, obtain financing necessary to operate our business, recruit and retain qualified personnel, manage any growth we may experience and successfully realize the benefits of our previous acquisitions and any other acquisitions and collaborative arrangements we may pursue; competition from pharmaceutical companies, outsourcing facilities and pharmacies; general economic and business conditions, including inflation and supply chain challenges; regulatory and legal risks and uncertainties related to our pharmacy operations and the pharmacy and pharmaceutical business in general, including the ongoing communications with the U.S. Food and Drug Administration relating to compliance and quality plans at our outsourcing facility in New Jersey; physician interest in and market acceptance of our current and any future formulations and compounding pharmacies generally. These and additional risks and uncertainties are more fully described in Harrow’s filings with the Securities and Exchange Commission (SEC), including its Annual Report on Form 10-K for the year ended December 31, 2025, and other filings with the SEC. Such documents may be read free of charge on the SEC's web site at sec.gov. Undue reliance should not be placed on forward-looking statements, which speak only as of the date they are made. Except as required by law, Harrow undertakes no obligation to update any forward-looking statements to reflect new information, events, or circumstances after the date they are made, or to reflect the occurrence of unanticipated events. Contacts: Mike Biega Vice President of Investor Relations and Communications mbiega@harrowinc.com 617-913-8890 i Byooviz is a trademark of Samsung Bioepis Co., Ltd. ii Lucentis is a trademark of Genentech, Inc.

Executive Chair Mark Crotty to continue guiding long-term strategic direction PERTH, Australia, July 14, 2026 /PRNewswire/ -- LumaCina, a global supplier and marketer of sterile injectable pharmaceutical products and a Bridgewest Group portfolio company, announced the appointment of Gary Bird as Chief Executive Officer. Bird was appointed by Executive Chair Mark Crotty, who will continue to lead LumaCina's long-term strategy, overseeing the company's platform development and guiding its next phase of expansion in close partnership with the incoming CEO. Continue Reading "Gary's appointment marks an important milestone in LumaCina's evolution as an independent pharmaceutical company." Post this Gary Bird, Chief Executive Officer, LumaCina LumaCina is a healthcare business focused on the sale and distribution of pharmaceutical and medical device products in the hospital setting. LumaCina supplies sterile injectable pharmaceutical drugs, spanning high potency, blow fill seal, multi format vials and more, all manufactured in Perth Australia, to customers in Australia, New Zealand, Asia and Northern Europe. Bird joins LumaCina at a pivotal stage in its evolution as it expands its portfolio, while strengthening strategic partnerships and broadening its presence across Australia and international markets. Bird brings more than three decades of leadership experience across the Australian pharmaceutical industry, with deep expertise in commercial strategy, market expansion and partnership-led growth. Over the past 13 years, he has led and represented companies including Orion Pharma, Medreich and Meda, working across pharmaceutical distribution, contract manufacturing, specialty medicines and consumer healthcare. Earlier in his career, Bird held senior leadership roles with Johnson & Johnson, Sanofi-Aventis and Pharmacia, building extensive commercial experience across Australia and the Asia-Pacific region. Bird served as a board member of Heartkids Australia and was an elected member of local government (Councilor of the Municipality of Hunters Hill, NSW Australia). He is a graduate of the Asialink Business Leaders Program (University of Melbourne) and holds a degree in Medical Science from the University of Sydney. "LumaCina has reached a point where the opportunity ahead requires a leader with both deep pharmaceutical expertise and a proven ability to build enduring commercial partnerships," said Mark Crotty, Executive Chair of LumaCina. "That combination made Gary the outstanding choice to lead the business." "Throughout his career, Gary has consistently built strong businesses by developing trusted customer relationships and delivering sustainable commercial outcomes. LumaCina has established a solid foundation, and I look forward to continuing to guide its long-term vision while working alongside Gary as we strengthen and expand the company's position as a trusted supplier of sterile injectable medicines." Bird has already spent time working with LumaCina's leadership team through the company's strategic planning and business review process, providing him with a strong understanding of the business, its customers and its priorities. "What attracted me to LumaCina is the company's values, the quality of its people and the opportunity to establish LumaCina as a global pharmaceutical company," said Gary Bird, Chief Executive Officer of LumaCina. "Healthcare systems are increasingly reliant on trusted partners that can consistently deliver high-quality essential medicines. LumaCina is well positioned to meet that need through a growing portfolio, strong commercial partnerships and an unwavering commitment to quality, reliability and customer service. I look forward to working with our team, customers, suppliers, Mark, the Board and Bridgewest Group as we continue building a stronger, more resilient pharmaceutical business." Bridgewest Group welcomed Bird's appointment and Crotty's continued leadership. "Gary's appointment marks an important milestone in LumaCina's evolution as an independent pharmaceutical company," said Dr. Masood Tayebi, Co-Founder and CEO of Bridgewest Group. "Mark has provided strong leadership as the architect of LumaCina's long-term strategy and platform development, creating a durable foundation for future growth. With Gary leading the business and Mark continuing in his strategic role as Executive Chair, LumaCina has a leadership structure that combines continuity, deep sector expertise and commercial execution capability. We are confident they will continue strengthening the company's position as a trusted supplier of sterile injectable medicines." About LumaCina LumaCina is a healthcare business focused on the sale and distribution of pharmaceutical and medical device products in the hospital setting. LumaCina supplies sterile injectable pharmaceutical drugs, spanning high potency, blow fill seal, multi format vials and more, all manufactured in Perth Australia, to customers in Australia, New Zealand, Asia and Northern Europe. Looking forward, LumaCina is aggressively expanding capabilities, infrastructure, and industry partnerships, growing a robust pipeline of high-quality medications through an acquisition and licencing program. LumaCina is a Bridgewest Group Portfolio Company. Frequently Asked Questions (FAQ) What does LumaCina do? LumaCina is a global pharmaceutical company specializing in sterile injectable hospital medicines. It is aggressively expanding capabilities, and growing a robust pipeline of high quality medications through an acquisition and licencing program. What essential medicines does LumaCina supply? LumaCina supplies sterile injectable and hospital medicines used in critical care, surgical, emergency and inpatient treatment settings. Its portfolio includes: Analgesics: Morphine Local anesthetics: Lidocaine IV fluids and electrolytes: Sodium Chloride, Potassium Chloride Antiemetics: Metoclopramide Antiseptics / infection control: Chlorhexidine, Povidone-Iodine Additional essential injectable medicines used in acute hospital care environments What are sterile injectable medicines? Sterile injectable medicines are pharmaceutical products administered directly into the body under strictly controlled sterile manufacturing conditions. They are used in hospital and clinical settings where rapid, precise and reliable therapeutic delivery is required. Who is Mark Crotty at LumaCina? Mark Crotty is Executive Chair of LumaCina. He leads the company's long-term strategic direction and platform development, providing continuity and oversight as the business expands its sterile injectable portfolio and international footprint. Who is Gary Bird? Gary Bird is Chief Executive Officer of LumaCina. He brings more than 30 years of pharmaceutical leadership experience across Australia and the Asia-Pacific region, with expertise in commercial operations, pharmaceutical distribution, and healthcare partnerships. Contact: Media Relations [email protected]. SOURCE LumaCina 21% more press release views with Request a Demo