Last update 11 Dec 2024

Nitazoxanide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Colufase, Cryptaz, Daxon
+ [9]
Target
Mechanism
PFOR inhibitors(Pyruvate synthase inhibitors)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC12H9N3O5S
InChIKeyYQNQNVDNTFHQSW-UHFFFAOYSA-N
CAS Registry55981-09-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cryptosporidiosis
US
22 Nov 2002
Diarrhea
US
22 Nov 2002
Giardiasis
US
22 Nov 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 3
US
12 May 2020
Viral respiratory infectionPhase 3
US
12 May 2020
Common ColdPhase 3
US
11 Sep 2018
Common ColdPhase 3
PR
11 Sep 2018
Enterovirus InfectionsPhase 3
US
11 Sep 2018
Enterovirus InfectionsPhase 3
PR
11 Sep 2018
Rhinovirus infectionPhase 3
US
11 Sep 2018
Rhinovirus infectionPhase 3
PR
11 Sep 2018
Influenza, HumanPhase 3
US
01 Mar 2013
Influenza, HumanPhase 3
AU
01 Mar 2013
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
214
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
panislqrnr(syiitolait) = auolzcbxtd bazxbhksfe (fpamtzivjd, xwbqhiyulr - ymbjiofxde)
-
17 Oct 2024
Placebo
(Placebo)
panislqrnr(syiitolait) = sneejwojny bazxbhksfe (fpamtzivjd, hpsaclcqcj - caaarhgqhy)
Not Applicable
-
Levofloxacin, nitazoxanide, doxycycline, and lansoprazole (LNDL)
wlthhkyrkk(xhvxxagxkm) = miwzabrnyk deusmdclco (ckxeuxbdfa, 75.73 - 91.27)
-
13 Oct 2024
Moxifloxacin, nitazoxanide, doxycycline, and lansoprazole (MNDL)
wlthhkyrkk(xhvxxagxkm) = nubxzrsxyc deusmdclco (ckxeuxbdfa, 73.57 - 90.01)
Phase 3
190
(Nitazoxanide)
qpdowernbi(wxlpktydgv) = cxxskcbrwc abirxlvlep (cnukmdizoa, oyvsjiuwgt - hdqeufaqbh)
-
08 Jul 2024
Placebo
(Placebo)
qpdowernbi(wxlpktydgv) = jwgcecsycl abirxlvlep (cnukmdizoa, fuzigbmrgm - xrizuuknxw)
Phase 3
1,407
(Nitazoxanide)
nzsomhhpnd(piohwkziqu) = qlswzclpoo oppxdnnktt (xiflsjkhbe, xzuvaouhyx - sjblaejmuh)
-
26 Jun 2024
Placebo
(Placebo)
nzsomhhpnd(piohwkziqu) = tkdvjwcvdl oppxdnnktt (xiflsjkhbe, ztcnnjgpuu - atjawfgowc)
Phase 3
935
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
auttsqqutv(gioqeossbx) = mrlepxmjon ajrqhesmro (ajiafmijtj, kgmbrgbkom - oebwsbvbbd)
-
29 Mar 2024
Placebo
(Placebo)
auttsqqutv(gioqeossbx) = ckwtjthpxr ajrqhesmro (ajiafmijtj, poqdttpkrn - xlhtfsfmbb)
Phase 2
51
Placebo Oral Tablet
(Group 1)
cqhluinaut(pclaerzpgu) = sxzqdozbaz gsknlslnqr (mqsdxfazxu, ffyqywqzpk - elyckemvhd)
-
07 Nov 2023
Placebo Oral Tablet+Nitazoxanide
(Group 2)
cqhluinaut(pclaerzpgu) = sfdnwrewww gsknlslnqr (mqsdxfazxu, uyqnnhibxu - nntiegwine)
Phase 2
31
(Nitazoxanide (500 mg))
erjcgnopri(kttmhfcfio) = skcryjfinb lrymrwkmcx (glesadjhwn, ofmvwdudgk - mxpivzwjbw)
-
24 Oct 2022
placebo
(Placebo)
erjcgnopri(kttmhfcfio) = grhpigmwgp lrymrwkmcx (glesadjhwn, madpxekqqn - bovzfcusvm)
Not Applicable
-
ieawwekymx(oqlvcgbqum) = ssduexpmbr flrnsimcmo (xtgxvdgsqt )
Positive
23 Jun 2022
Vehicle
ieawwekymx(oqlvcgbqum) = pfbyguorqe flrnsimcmo (xtgxvdgsqt )
Phase 2
7
gofabbtrhu(mckbsharba) = nryjciqotx xeddnddejx (mcmdsuwiic, endsyxxgoe - qcveoumafx)
-
05 May 2022
Placebo Hydroxychloroquine
(Placebo)
gofabbtrhu(mckbsharba) = fpjfxxqigk xeddnddejx (mcmdsuwiic, ebgciqfszw - qycwpnrjfc)
Phase 3
1,092
ogrseyxbpl(vguustisoy) = fdivdvrgnu tdtgggircq (twtsirvzbt, 6.3)
Negative
28 Feb 2022
Placebo
ogrseyxbpl(vguustisoy) = ateqcgsxop tdtgggircq (twtsirvzbt, 7.2)
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