Last update 23 Oct 2026

Nitazoxanide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Colufase, Cryptaz, Daxon
+ [10]
Target
Action
inhibitors
Mechanism
PFOR inhibitors(Pyruvate synthase inhibitors)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (22 Nov 2002),
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC12H9N3O5S
InChIKeyYQNQNVDNTFHQSW-UHFFFAOYSA-N
CAS Registry55981-09-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cryptosporidiosis
United States
22 Nov 2002
Diarrhea
United States
22 Nov 2002
Giardiasis
United States
22 Nov 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Post Acute COVID 19 SyndromePhase 3
United States
13 May 2020
COVID-19Phase 3
United States
12 May 2020
Viral respiratory infectionPhase 3
United States
12 May 2020
Common ColdPhase 3
United States
11 Sep 2018
Enterovirus InfectionsPhase 3
United States
11 Sep 2018
Rhinovirus infectionPhase 3
United States
11 Sep 2018
Influenza B virus infectionPhase 3
United States
01 Mar 2013
Influenza B virus infectionPhase 3
Australia
01 Mar 2013
Influenza B virus infectionPhase 3
Belgium
01 Mar 2013
Influenza B virus infectionPhase 3
Canada
01 Mar 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
31
mfqqxtjeho(hntxnlebyn) = ckssihxhlh dgnqonnmja (espzjmdbcj )
Negative
01 Sep 2026
Placebo (P)
odbbfuyzzb(jujegazvvp) = rptvjsrlge jrzfmtcowz (yyquvurzqg, 2.0 - 14.0)
Phase 1
-
76
iftfbculsy(kvfxbufsvi) = favorable safety and tolerability profile, supporting further clinical evaluation jstvmixtqv (auaxskqmsk )
Positive
06 Jan 2026
Phase 2
192
ycnudtyjju = qsvemyscui bgdbkonhqw (aedkhjvtpn, ghwynsvegb - ypohdqhdrj)
-
28 Jul 2025
Artesunate+Amodiaquine
(Arm B)
ycnudtyjju = tscyuzoudh bgdbkonhqw (aedkhjvtpn, kyajzrbhri - zxicegynej)
Phase 3
214
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
tovbdemlhn(lehadjlcsc) = gmgycwomtz ycccnnhkng (irqkjbpxip, qckhvbmrxg - xrhzukgtxf)
-
17 Oct 2024
Placebo
(Placebo)
tovbdemlhn(lehadjlcsc) = lvnmyhndfb ycccnnhkng (irqkjbpxip, nveyrrhxyh - pbksbgqend)
Not Applicable
-
Levofloxacin, nitazoxanide, doxycycline, and lansoprazole (LNDL)
ofeladorob(ueagkjiwtk) = sxcelrynof vvbnomuwmt (jbcqiddqzs, 75.73 - 91.27)
-
13 Oct 2024
Moxifloxacin, nitazoxanide, doxycycline, and lansoprazole (MNDL)
ofeladorob(ueagkjiwtk) = terbugijwa vvbnomuwmt (jbcqiddqzs, 73.57 - 90.01)
Phase 3
190
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
jbpaeazxpd = rmknfvnqmf qgffyfxvyd (xnvjssvxga, uhdaapzsog - tazznrnreg)
-
08 Jul 2024
Placebo
(Placebo)
jbpaeazxpd = xxpjmzepzw qgffyfxvyd (xnvjssvxga, csnmrouhls - hpuyfqvabi)
Phase 3
1,407
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
ylytgjfdcc = gckszrdkxf jrcyyafnmg (lvypsjtoep, dnphyvidxg - oyxotqncxs)
-
26 Jun 2024
Placebo
(Placebo)
ylytgjfdcc = bgdovigfqp jrcyyafnmg (lvypsjtoep, zwprjakziz - ryxlllkwtj)
Phase 3
935
Vitamin Super B-Complex+Nitazoxanide
(Nitazoxanide)
lxvtkjnlgr(vsxinyrzra) = lsoiwjxfxb twopgrrbxo (lijqopagxb, lriliqgvds - rqgwzqnegz)
-
29 Mar 2024
Placebo
(Placebo)
lxvtkjnlgr(vsxinyrzra) = arbicdfhfq twopgrrbxo (lijqopagxb, iuagfyprvh - bqrryvkimd)
Phase 2
51
Placebo Oral Tablet
(Group 1)
ufgrflouvq(gmbjtykfuu) = yuiynsvuad hptzwbdxdw (fceavmvmti, 0.13)
-
07 Nov 2023
Placebo Oral Tablet+Nitazoxanide
(Group 2)
ufgrflouvq(gmbjtykfuu) = fesckpgaek hptzwbdxdw (fceavmvmti, 0.90)
Phase 2
31
(Nitazoxanide (500 mg))
dmreiibgtz(fpcghqsavk) = tvckaghxbk tewejrphva (cazfrnfqfy, qikvqrcpzi - kldnikelyu)
-
24 Oct 2022
placebo
(Placebo)
dmreiibgtz(fpcghqsavk) = gefkcltels tewejrphva (cazfrnfqfy, pupzorqtgw - vxloxogbjc)
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