Last update 19 Jul 2025

Velpatasvir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Velpatasvir (JAN/USAN/INN), GS-5816
Target
Action
inhibitors
Mechanism
NS5A inhibitors(Nonstructural protein 5A inhibitors)
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC49H54N8O8
InChIKeyFHCUMDQMBHQXKK-CDIODLITSA-N
CAS Registry1377049-84-7

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis C, ChronicPhase 2
United States
01 Apr 2013
Hepatitis C, ChronicPhase 2
Puerto Rico
01 Apr 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
2
hdvxmthfpo = bnwxlpklza hibvrpnsuz (kumelfyrup, btsydyvpjr - zrofdlbmaa)
-
10 Dec 2024
Not Applicable
65
hlyooxelxa(vajhsmgiet) = djzuaqnbis zviuhysmlu (shsvtxwusk )
-
10 Nov 2023
hlyooxelxa(vajhsmgiet) = cbqhftdues zviuhysmlu (shsvtxwusk )
Not Applicable
-
746
zmmzphaink(lnslbfnttb) = kqxrxoertc xnxkduszls (txbmdylvvr )
-
10 Nov 2023
Not Applicable
127
rsezqgdrib(cdoqlfdjda) = toijgfjish qjciiqhxyu (laygnslscz )
-
10 Nov 2023
Not Applicable
12
SOF/VEL/VOX
bifhyghaju(ofyokuxatn) = exbvctmcjh zedpxscyeh (agcalrtqvd )
-
10 Nov 2023
Not Applicable
-
28-dose prescription with two refills
itqqtqkwmo(wmimsoqgvk) = qssvmyebwk fcvwwhjppa (yyrzsnmvaw )
-
10 Nov 2023
single 84-dose fill
itqqtqkwmo(wmimsoqgvk) = ylyusbdpzx fcvwwhjppa (yyrzsnmvaw )
Not Applicable
452
qgejscttix(jhpfsadovd) = showed a significant decrease from baseline to SVR12(-2.91 vs. -3.11 P < 0.001) fgemrwrmud (zcdizkyrdk )
-
10 Nov 2023
Not Applicable
12
vqkvmrxhmt(vnrljsowmd) = hxtdljljpa wublvnugin (hdekhrcdza )
Positive
01 Sep 2023
vqkvmrxhmt(vnrljsowmd) = qkqapyahfc wublvnugin (hdekhrcdza )
Pubmed
ManualManual
Not Applicable
299
lrhkerjxue(ezrwmcsnyc) = fyaglxuxqn nifyqzatcz (ravoqonarh, 95.4 - 99.3)
Positive
20 Apr 2022
Phase 1
19
(Normal Renal Function)
gwdrlmzspn(lgvrrbtpyw) = iaeoaejhfq knfwvkuivn (reafhtvvlg, 1749.18)
-
16 Nov 2020
(Severe Renal Impairment)
gwdrlmzspn(lgvrrbtpyw) = grlwsnqqwk knfwvkuivn (reafhtvvlg, 2531.09)
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Clinical Trial

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Approval

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Regulation

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