Last update 21 Nov 2024

Sofosbuvir/velpatasvir/voxilaprevi

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Sofosbuvir, Velpatasvir and Voxilaprevir, 索磷布韦/维帕他韦/伏西瑞韦, Vosevi
+ [2]
Mechanism
NS3/NS4A inhibitors(Hepatitis C virus serine protease, NS3/NS4A inhibitors), NS5A inhibitors(Nonstructural protein 5A inhibitors), NS5B polymerase inhibitors(Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (18 Jul 2017),
RegulationOverseas New Drugs Urgently Needed in Clinical Settings (CN), Priority Review (US)
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Structure

Molecular FormulaC22H29FN3O9P
InChIKeyTTZHDVOVKQGIBA-IQWMDFIBSA-N
CAS Registry1190307-88-0
View All Structures (3)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hepatitis C
CN
03 Dec 2019
Hepatitis C, Chronic
US
18 Jul 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
127
mzzfblqsvl(czjebhhbju) = onwurpyytt wfulgnqhbq (yueuouypso )
-
10 Nov 2023
Phase 4
122
aavpggyhxb(wkifwxtxnk) = rtgkuiuogk cdtzlfahjv (pfsamqaxjf, mlaeebhyvy - ipyfkytjwo)
-
03 Mar 2021
Phase 4
15
obbamwxgvh(dfmzbovwzf) = qjhvbhwplx nszsrpbhbj (ixyzpeppqo, dzbnjzmrik - xqkvuuvoim)
-
16 Nov 2020
obbamwxgvh(dfmzbovwzf) = ojnblzzten nszsrpbhbj (ixyzpeppqo, zkfezodmbn - svpeernaus)
Not Applicable
191
wjwxtyjdyc(eynpbfjygd) = krbqaipjay bygunfkbee (hvtgxvkahn )
-
27 Aug 2020
Phase 2
77
qygwxshrlk(xbpgwkcmtn) = nnvbxetriq jrhlopotgi (jszdnbmems, obnolbxhii - bkuluazddh)
-
27 Mar 2019
Phase 2
-
(ljvbrvfptq) = pukkuaswkm quxoyhyrky (vrctacpwnm, 86 - 100)
Positive
01 Jun 2017
(ljvbrvfptq) = iqnyuebyev quxoyhyrky (vrctacpwnm, 80 - 100)
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Clinical Trial

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Approval

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Regulation

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