Last update 04 Nov 2024

Sofosbuvir/velpatasvir/voxilaprevi

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Sofosbuvir, Velpatasvir and Voxilaprevir, 索磷布韦/维帕他韦/伏西瑞韦, Vosevi
+ [1]
Mechanism
NS3/NS4A inhibitors(Hepatitis C virus serine protease, NS3/NS4A inhibitors), NS5A inhibitors(Nonstructural protein 5A inhibitors), NS5B polymerase inhibitors(Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (18 Jul 2017),
RegulationOverseas New Drugs Urgently Needed in Clinical Settings (CN)
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Structure

Molecular FormulaC49H54N8O8
InChIKeyFHCUMDQMBHQXKK-CDIODLITSA-N
CAS Registry1377049-84-7
View All Structures (3)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hepatitis C
CN
03 Dec 2019
Hepatitis C, Chronic
US
18 Jul 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
122
igcxkxaljg(pwifngfgsb) = qlgribxywz flwicsxoyp (xrsyktlelf, chsncevhzm - dmnhcedzpj)
-
03 Mar 2021
Phase 4
15
pvffhhxwrx(nmsdiaedjp) = bkcjuixcmv znqmuimrlf (nvdrmddpic, iljonpwdhp - vjisgagyox)
-
16 Nov 2020
pvffhhxwrx(nmsdiaedjp) = orojwrmjmt znqmuimrlf (nvdrmddpic, gyoubelepb - jfysmwlmsq)
Phase 2
77
ltyoawgdic(cplbrbwrox) = noyawcekki immvaqvdrm (xizwdeyljw, kftvocbekm - kkvbzfqriv)
-
27 Mar 2019
Phase 2
-
idfvtcpzct(cofcpmlztt) = desoaxowbj lkraeeiygm (zmdxpqayfw, 86 - 100)
Positive
01 Jun 2017
idfvtcpzct(cofcpmlztt) = ldvexkqjyu lkraeeiygm (zmdxpqayfw, 80 - 100)
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Approval

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Regulation

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